Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FQT67_RS10275 Genome accession   NZ_LR595857
Coordinates   2063215..2064486 (-) Length   423 a.a.
NCBI ID   WP_143936425.1    Uniprot ID   A0A9X9R4I2
Organism   Streptococcus sp. NCTC 11567 strain NCTC11567     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2058215..2069486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT67_RS10245 (NCTC11567_02121) - 2058270..2059832 (-) 1563 WP_143936424.1 DUF2079 domain-containing protein -
  FQT67_RS10250 (NCTC11567_02123) - 2060169..2060474 (-) 306 WP_003058733.1 DUF1292 domain-containing protein -
  FQT67_RS10255 (NCTC11567_02124) ruvX 2060485..2060904 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  FQT67_RS10260 (NCTC11567_02125) - 2060901..2061170 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  FQT67_RS10265 (NCTC11567_02126) spx 2061282..2061680 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  FQT67_RS10270 (NCTC11567_02127) recA 2061974..2063110 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  FQT67_RS10275 (NCTC11567_02128) cinA 2063215..2064486 (-) 1272 WP_143936425.1 competence/damage-inducible protein A Machinery gene
  FQT67_RS10280 (NCTC11567_02129) - 2064610..2064963 (-) 354 WP_003058738.1 VOC family protein -
  FQT67_RS10285 (NCTC11567_02130) - 2064966..2065538 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  FQT67_RS10290 (NCTC11567_02131) ruvA 2065548..2066141 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA -
  FQT67_RS10295 (NCTC11567_02132) - 2066143..2067363 (-) 1221 Protein_1979 MFS transporter -
  FQT67_RS10300 (NCTC11567_02134) mutL 2067374..2069356 (-) 1983 WP_046177146.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46019.47 Da        Isoelectric Point: 4.7637

>NTDB_id=1128455 FQT67_RS10275 WP_143936425.1 2063215..2064486(-) (cinA) [Streptococcus sp. NCTC 11567 strain NCTC11567]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVIYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1128455 FQT67_RS10275 WP_143936425.1 2063215..2064486(-) (cinA) [Streptococcus sp. NCTC 11567 strain NCTC11567]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGATTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

70.743

98.582

0.697
  cinA Streptococcus mitis NCTC 12261

69.784

98.582

0.688
  cinA Streptococcus pneumoniae TIGR4

69.544

98.582

0.686
  cinA Streptococcus pneumoniae Rx1

69.544

98.582

0.686
  cinA Streptococcus pneumoniae R6

69.544

98.582

0.686
  cinA Streptococcus pneumoniae D39

69.305

98.582

0.683
  cinA Streptococcus suis isolate S10

52.404

98.345

0.515
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449

Multiple sequence alignment