Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL23_RS10180 Genome accession   NZ_LR594049
Coordinates   2109417..2110673 (-) Length   418 a.a.
NCBI ID   WP_045773039.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2104417..2115673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS10150 (NCTC10231_02031) - 2105874..2106185 (-) 312 WP_008809966.1 DUF1292 domain-containing protein -
  FGL23_RS10155 (NCTC10231_02032) ruvX 2106207..2106626 (-) 420 WP_061593908.1 Holliday junction resolvase RuvX -
  FGL23_RS10160 (NCTC10231_02033) - 2106626..2106892 (-) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  FGL23_RS10165 (NCTC10231_02034) - 2107004..2107576 (-) 573 WP_061603236.1 SP0191 family lipoprotein -
  FGL23_RS10170 (NCTC10231_02035) spx 2107722..2108120 (-) 399 WP_008809970.1 transcriptional regulator Spx -
  FGL23_RS10175 (NCTC10231_02036) recA 2108207..2109358 (-) 1152 WP_008809971.1 recombinase RecA Machinery gene
  FGL23_RS10180 (NCTC10231_02037) cinA 2109417..2110673 (-) 1257 WP_045773039.1 competence/damage-inducible protein A Machinery gene
  FGL23_RS10190 (NCTC10231_02038) - 2110943..2111353 (+) 411 WP_061603237.1 helix-turn-helix domain-containing protein -
  FGL23_RS10195 (NCTC10231_02039) - 2111404..2112063 (-) 660 WP_061603238.1 CPBP family intramembrane glutamic endopeptidase -
  FGL23_RS10200 (NCTC10231_02040) - 2112068..2112622 (-) 555 WP_061603239.1 DNA-3-methyladenine glycosylase I -
  FGL23_RS10205 (NCTC10231_02041) ruvA 2112632..2113222 (-) 591 WP_045773043.1 Holliday junction branch migration protein RuvA -
  FGL23_RS10210 (NCTC10231_02042) - 2113392..2113895 (+) 504 WP_046164533.1 helix-turn-helix domain-containing protein -
  FGL23_RS10215 (NCTC10231_02043) - 2113879..2114400 (+) 522 WP_061603240.1 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44703.62 Da        Isoelectric Point: 4.5254

>NTDB_id=1128007 FGL23_RS10180 WP_045773039.1 2109417..2110673(-) (cinA) [Streptococcus gordonii strain NCTC10231]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELSFDPDAVEKLDHFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGLVEDNGVTYVVLPGPPSELKPM
VNNELVPILSTGQKLYSRVLRFFGIGESQLVTVLSEMIDQQSDPTIAPYAKTGEVTLRLSTKALSQAEADTKFDAVEKEI
LSHKTFEDQSLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSRML
DIPLGELEEHGVVSAFTAGEMAEQARKLTESDLAVSLTGVAGPDSLEGHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1128007 FGL23_RS10180 WP_045773039.1 2109417..2110673(-) (cinA) [Streptococcus gordonii strain NCTC10231]
ATGAAAGCAGAAATTATTGCTGTGGGCACAGAGATTCTGACGGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
GAAACTGGCGAGTCTAGGGATTGATGTCTATTTTCAGACAGCTGTAGGGGACAATGAAAATCGTCTCCTCTCTATCCTAG
AGATTGCAAAAGGACGTAGTAATCTAATTATCTTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTAGGTCGAGAGTTGAGTTTCGACCCTGATGCTGTGGAAAAGTTGGATCATTTTTTTGCCAGCCGACC
AGATTATGCTCGAACGCCCAACAATGAGCGTCAGGCCCAGCTGGTTGAAGGCTCAACTCCGTTACCAAATGCGACTGGTT
TAGCTGTTGGCGGTTTAGTAGAAGATAATGGGGTGACTTATGTAGTTCTGCCTGGTCCGCCTAGCGAGCTCAAACCTATG
GTCAATAACGAGTTGGTTCCCATCTTATCCACAGGTCAAAAGTTGTACTCACGAGTGTTGCGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTGTTTTGTCAGAGATGATTGATCAGCAAAGTGACCCCACCATTGCTCCTTATGCAAAGACAGGGG
AAGTTACCCTACGACTGTCCACCAAGGCCTTGAGTCAGGCAGAAGCCGACACCAAGTTTGATGCTGTGGAAAAGGAAATT
TTGTCACATAAGACTTTTGAAGACCAGTCTCTGTCAGAGATTTTCTATGGTTATGGGGATGACAATTCCTTGGCTCAGGT
GGCTTTTGACTTGCTCAAGAGTCAAGGAAAGACGATTTCAGCAGCAGAGAGTCTGACAGCAGGTCTCTTCCAAGCGACTT
TGGCAGATTTTGCTGGAGCTTCAGCTATTTTTTCAGGTGGCTTCGTCACCTATAGCATGGAGGAAAAGAGCCGGATGCTG
GACATTCCGCTGGGAGAGCTGGAGGAACATGGGGTTGTTTCAGCTTTTACGGCTGGGGAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTGGCTGTCAGTCTGACAGGCGTGGCTGGACCAGATTCACTGGAAGGCCATCCAGCAGGGACCG
TTTTTATCGGTTTAGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGCAGTCGCCGAGATGTACGA
AAAATCGCTGTTCTGCACGCCTTTAACCTAGTGCGAAAGACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.458

99.761

0.773
  cinA Streptococcus mitis NCTC 12261

76.978

99.761

0.768
  cinA Streptococcus pneumoniae TIGR4

76.499

99.761

0.763
  cinA Streptococcus pneumoniae Rx1

76.499

99.761

0.763
  cinA Streptococcus pneumoniae R6

76.499

99.761

0.763
  cinA Streptococcus pneumoniae D39

76.259

99.761

0.761
  cinA Streptococcus mutans UA159

74.402

100

0.744
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

100

0.469

Multiple sequence alignment