Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL18_RS10105 Genome accession   NZ_LR594046
Coordinates   2095993..2097264 (-) Length   423 a.a.
NCBI ID   WP_138126792.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2090993..2102264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS10075 (NCTC6403_02070) - 2091049..2092611 (-) 1563 WP_138126788.1 DUF2079 domain-containing protein -
  FGL18_RS10080 (NCTC6403_02072) - 2092948..2093253 (-) 306 WP_003045716.1 DUF1292 domain-containing protein -
  FGL18_RS10085 (NCTC6403_02073) ruvX 2093264..2093683 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  FGL18_RS10090 (NCTC6403_02074) - 2093680..2093949 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  FGL18_RS10095 (NCTC6403_02075) spx 2094060..2094458 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  FGL18_RS10100 (NCTC6403_02076) recA 2094752..2095888 (-) 1137 WP_138126790.1 recombinase RecA Machinery gene
  FGL18_RS10105 (NCTC6403_02077) cinA 2095993..2097264 (-) 1272 WP_138126792.1 competence/damage-inducible protein A Machinery gene
  FGL18_RS10110 (NCTC6403_02078) - 2097388..2097741 (-) 354 WP_003058738.1 VOC family protein -
  FGL18_RS10115 (NCTC6403_02079) - 2097744..2098316 (-) 573 WP_138126794.1 DNA-3-methyladenine glycosylase I -
  FGL18_RS10120 (NCTC6403_02080) ruvA 2098326..2098919 (-) 594 WP_138126796.1 Holliday junction branch migration protein RuvA -
  FGL18_RS10125 (NCTC6403_02081) - 2098921..2100141 (-) 1221 WP_138126798.1 MFS transporter -
  FGL18_RS10130 (NCTC6403_02082) mutL 2100152..2102134 (-) 1983 WP_138126800.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46065.51 Da        Isoelectric Point: 4.7069

>NTDB_id=1127825 FGL18_RS10105 WP_138126792.1 2095993..2097264(-) (cinA) [Streptococcus dysgalactiae strain NCTC6403]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDDFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTFASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLISHGVVSAYTAEKMAEQTRLLTGADIGVSLTGVAGPDMLEDQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1127825 FGL18_RS10105 WP_138126792.1 2095993..2097264(-) (cinA) [Streptococcus dysgalactiae strain NCTC6403]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGCGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTAGACGATTTTTATGCCAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCAGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACTATTGCACCTTATGCTAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAGTATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTTGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTAACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAACACG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCTGGACCAGATATGTTGGAGGACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.868

100

0.719
  cinA Streptococcus mitis SK321

70.504

98.582

0.695
  cinA Streptococcus mitis NCTC 12261

69.544

98.582

0.686
  cinA Streptococcus pneumoniae TIGR4

69.305

98.582

0.683
  cinA Streptococcus pneumoniae Rx1

69.305

98.582

0.683
  cinA Streptococcus pneumoniae R6

69.305

98.582

0.683
  cinA Streptococcus pneumoniae D39

69.065

98.582

0.681
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449

Multiple sequence alignment