Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL16_RS00440 Genome accession   NZ_LR594043
Coordinates   73656..74714 (+) Length   352 a.a.
NCBI ID   WP_014735253.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10237     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 68656..79714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS00425 (NCTC10237_00082) mutL 70110..72047 (+) 1938 WP_014735250.1 DNA mismatch repair endonuclease MutL -
  FGL16_RS00430 (NCTC10237_00083) ruvA 72086..72676 (+) 591 WP_014735251.1 Holliday junction branch migration protein RuvA -
  FGL16_RS00435 (NCTC10237_00084) - 73050..73619 (+) 570 WP_014735252.1 DNA-3-methyladenine glycosylase I -
  FGL16_RS00440 (NCTC10237_00085) cinA 73656..74714 (+) 1059 WP_014735253.1 competence/damage-inducible protein A Machinery gene
  FGL16_RS00445 (NCTC10237_00086) recA 74766..75917 (+) 1152 WP_014735254.1 recombinase RecA Machinery gene
  FGL16_RS00450 (NCTC10237_00087) spx 76153..76551 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  FGL16_RS00455 (NCTC10237_00088) - 76651..76917 (+) 267 WP_014735255.1 IreB family regulatory phosphoprotein -
  FGL16_RS00460 (NCTC10237_00089) ruvX 76917..77336 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  FGL16_RS00465 (NCTC10237_00090) - 77348..77668 (+) 321 WP_014735256.1 DUF1292 domain-containing protein -
  FGL16_RS00470 (NCTC10237_00091) - 77875..78411 (+) 537 WP_050572628.1 nucleotidyltransferase family protein -
  FGL16_RS00475 (NCTC10237_00092) - 78561..79453 (+) 893 Protein_68 IS982 family transposase -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38659.00 Da        Isoelectric Point: 4.4299

>NTDB_id=1127605 FGL16_RS00440 WP_014735253.1 73656..74714(+) (cinA) [Streptococcus suis strain NCTC10237]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTSNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLREYFYAYGEENSLVQTVAERLVEKNKSIAIVEQGTGGLLQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSG
ISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=1127605 FGL16_RS00440 WP_014735253.1 73656..74714(+) (cinA) [Streptococcus suis strain NCTC10237]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACATCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGTTTTTTTGGTATTGG
TGAAAGCCAGTTAGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGATAAACTGAGAGAATATTTCTATGCCTACGGTGAGGAAAATAGTCTGGTACAGACAGTAGCAGAGCG
ATTGGTGGAAAAGAATAAAAGCATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGATTTGGGTTTGGCTG
TGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAACGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGT
ATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGTGGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTT
TGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

84.733

100

0.946
  cinA Streptococcus pneumoniae R6

69.966

83.239

0.582
  cinA Streptococcus mitis SK321

69.966

83.239

0.582
  cinA Streptococcus pneumoniae TIGR4

69.966

83.239

0.582
  cinA Streptococcus pneumoniae Rx1

69.966

83.239

0.582
  cinA Streptococcus pneumoniae D39

69.625

83.239

0.58
  cinA Streptococcus mitis NCTC 12261

69.283

83.239

0.577
  cinA Streptococcus mutans UA159

69.31

82.386

0.571
  cinA Bacillus subtilis subsp. subtilis str. 168

48.611

81.818

0.398

Multiple sequence alignment