Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL12_RS10425 Genome accession   NZ_LR594041
Coordinates   2148364..2149620 (-) Length   418 a.a.
NCBI ID   WP_012131015.1    Uniprot ID   A8AZT4
Organism   Streptococcus gordonii strain NCTC9124     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2143364..2154620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS10395 (NCTC9124_02097) - 2144822..2145133 (-) 312 WP_008809966.1 DUF1292 domain-containing protein -
  FGL12_RS10400 (NCTC9124_02098) ruvX 2145155..2145574 (-) 420 WP_012131012.1 Holliday junction resolvase RuvX -
  FGL12_RS10405 (NCTC9124_02099) - 2145574..2145840 (-) 267 WP_008809968.1 IreB family regulatory phosphoprotein -
  FGL12_RS10410 (NCTC9124_02100) - 2145952..2146524 (-) 573 WP_012131013.1 SP0191 family lipoprotein -
  FGL12_RS10415 (NCTC9124_02101) spx 2146670..2147068 (-) 399 WP_008809970.1 transcriptional regulator Spx -
  FGL12_RS10420 (NCTC9124_02102) recA 2147155..2148306 (-) 1152 WP_012131014.1 recombinase RecA Machinery gene
  FGL12_RS10425 (NCTC9124_02103) cinA 2148364..2149620 (-) 1257 WP_012131015.1 competence/damage-inducible protein A Machinery gene
  FGL12_RS10435 (NCTC9124_02104) - 2149895..2150305 (+) 411 WP_012131016.1 helix-turn-helix transcriptional regulator -
  FGL12_RS10440 (NCTC9124_02105) - 2150357..2151016 (-) 660 WP_041789818.1 type II CAAX endopeptidase family protein -
  FGL12_RS10445 (NCTC9124_02106) - 2151021..2151575 (-) 555 WP_012131018.1 DNA-3-methyladenine glycosylase I -
  FGL12_RS10450 (NCTC9124_02107) ruvA 2151585..2152175 (-) 591 WP_012131019.1 Holliday junction branch migration protein RuvA -
  FGL12_RS10455 (NCTC9124_02108) - 2152345..2152848 (+) 504 WP_012131020.1 helix-turn-helix transcriptional regulator -
  FGL12_RS10460 (NCTC9124_02109) - 2152832..2153353 (+) 522 WP_012131021.1 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44694.70 Da        Isoelectric Point: 4.5224

>NTDB_id=1127533 FGL12_RS10425 WP_012131015.1 2148364..2149620(-) (cinA) [Streptococcus gordonii strain NCTC9124]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNESRLLSILEIAKGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELSFDPDAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLPNATGLAVGGILEVDGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIDQQSDPTIAPYAKTGEVTLRLSTKALSQAEADAKFEAVEKEI
LSHKTFEDQSLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASAIFSGGFVTYSMEEKSRML
DIPLGDLEEHGVVSAFTAGKMAEQARKLTESDLAVSLTGVAGPDSLEDHPAGTVFIGLASAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRSTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1127533 FGL12_RS10425 WP_012131015.1 2148364..2149620(-) (cinA) [Streptococcus gordonii strain NCTC9124]
ATGAAAGCAGAAATTATTGCTGTGGGCACAGAGATTCTGACGGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCGAGTCTGGGGATTGACGTCTACTTTCAGACAGCAGTAGGGGACAATGAAAGTCGTCTCCTCTCAATCCTAG
AGATTGCAAAAGGACGCAGTAATCTGATTATTCTGACAGGAGGCTTGGGGCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTTTTAGGTCGAGAGTTGAGTTTCGACCCTGATGCTGTGGAGAAGTTGGATCGTTTTTTTGCCAGCCGACC
AGATTATGCTCGAACGCCCAACAATGAGCGTCAGGCTCAGCTGGTTGAAGGCTCAACTCCGTTACCAAATGCGACTGGTT
TAGCTGTTGGCGGTATATTGGAAGTCGATGGAGTGACTTATGTAGTCCTACCCGGTCCACCTAGCGAGCTCAAACCCATG
GTCAATAACGAGCTGGTTCCCCTTTTATCCACAGGTCAAAAGTTGTACTCACGAGTATTACGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGATCAGCAAAGTGACCCTACCATTGCTCCTTATGCAAAGACAGGGG
AGGTTACCTTACGATTGTCCACCAAGGCCTTGAGTCAGGCAGAAGCTGACGCCAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGTCACATAAGACTTTTGAAGACCAGTCTCTGTCAGAGATTTTCTATGGTTATGGGGATGACAATTCCTTGGCTCAGGT
GGCTTTTGATTTGCTCAAGAGTCAAGGAAAGACGATTTCAGCAGCAGAGAGTCTGACAGCAGGTCTCTTCCAAGCAACCT
TGGCAGATTTTGCTGGAGCTTCAGCTATTTTTTCAGGTGGCTTCGTCACCTATAGCATGGAGGAAAAGAGCCGGATGCTG
GACATTCCGCTGGGAGACCTGGAGGAACATGGGGTTGTTTCAGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACCGAAAGCGACTTGGCTGTCAGTCTGACAGGTGTGGCTGGACCAGATTCACTAGAAGACCATCCAGCTGGAACTG
TTTTTATTGGCTTAGCTAGTGCTGCAGGAACGGAAACTATTAAGGTCAATATTGCTGGACGTAGCCGGCGAGATGTACGA
AAAATCGCTGTTCTGCACGCCTTTAACCTAGTGCGAAGTACTTTATTAAATAGTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZT4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

78.417

99.761

0.782
  cinA Streptococcus mitis NCTC 12261

77.938

99.761

0.778
  cinA Streptococcus pneumoniae TIGR4

76.978

99.761

0.768
  cinA Streptococcus pneumoniae Rx1

76.978

99.761

0.768
  cinA Streptococcus pneumoniae R6

76.978

99.761

0.768
  cinA Streptococcus pneumoniae D39

76.739

99.761

0.766
  cinA Streptococcus mutans UA159

74.641

100

0.746
  cinA Streptococcus suis isolate S10

55.529

99.522

0.553
  cinA Bacillus subtilis subsp. subtilis str. 168

46.377

99.043

0.459

Multiple sequence alignment