Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGL00_RS10605 Genome accession   NZ_LR594034
Coordinates   2134192..2135463 (-) Length   423 a.a.
NCBI ID   WP_138098774.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2129192..2140463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL00_RS10575 (NCTC8546_02179) - 2129247..2130809 (-) 1563 WP_138084080.1 DUF2079 domain-containing protein -
  FGL00_RS10580 (NCTC8546_02181) - 2131146..2131451 (-) 306 WP_003058733.1 DUF1292 domain-containing protein -
  FGL00_RS10585 (NCTC8546_02182) ruvX 2131462..2131881 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  FGL00_RS10590 (NCTC8546_02183) - 2131878..2132147 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  FGL00_RS10595 (NCTC8546_02184) spx 2132259..2132657 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  FGL00_RS10600 (NCTC8546_02186) recA 2132951..2134087 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  FGL00_RS10605 (NCTC8546_02187) cinA 2134192..2135463 (-) 1272 WP_138098774.1 competence/damage-inducible protein A Machinery gene
  FGL00_RS10610 (NCTC8546_02188) - 2135587..2135940 (-) 354 WP_003058738.1 VOC family protein -
  FGL00_RS10615 (NCTC8546_02189) - 2135943..2136515 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  FGL00_RS10620 (NCTC8546_02190) ruvA 2136525..2137118 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA -
  FGL00_RS10625 (NCTC8546_02191) - 2137120..2138340 (-) 1221 WP_003058727.1 MFS transporter -
  FGL00_RS10630 (NCTC8546_02192) mutL 2138351..2140333 (-) 1983 WP_012767642.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46033.49 Da        Isoelectric Point: 4.7637

>NTDB_id=1127268 FGL00_RS10605 WP_138098774.1 2134192..2135463(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRIRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1127268 FGL00_RS10605 WP_138098774.1 2134192..2135463(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC8546]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAATCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

70.743

98.582

0.697
  cinA Streptococcus mitis NCTC 12261

69.784

98.582

0.688
  cinA Streptococcus pneumoniae TIGR4

69.544

98.582

0.686
  cinA Streptococcus pneumoniae Rx1

69.544

98.582

0.686
  cinA Streptococcus pneumoniae R6

69.544

98.582

0.686
  cinA Streptococcus pneumoniae D39

69.305

98.582

0.683
  cinA Streptococcus suis isolate S10

52.404

98.345

0.515
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

98.818

0.447

Multiple sequence alignment