Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGK99_RS09485 Genome accession   NZ_LR594033
Coordinates   1986231..1987502 (-) Length   423 a.a.
NCBI ID   WP_138119896.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1981231..1992502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS09460 (NCTC4675_01922) - 1983117..1983416 (-) 300 WP_012516437.1 DUF1292 domain-containing protein -
  FGK99_RS09465 (NCTC4675_01923) ruvX 1983426..1983845 (-) 420 WP_015898660.1 Holliday junction resolvase RuvX -
  FGK99_RS09470 (NCTC4675_01924) - 1983842..1984111 (-) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  FGK99_RS09475 (NCTC4675_01925) spx 1984226..1984624 (-) 399 WP_012516440.1 transcriptional regulator Spx -
  FGK99_RS09480 (NCTC4675_01926) recA 1985001..1986137 (-) 1137 WP_012516441.1 recombinase RecA Machinery gene
  FGK99_RS09485 (NCTC4675_01927) cinA 1986231..1987502 (-) 1272 WP_138119896.1 competence/damage-inducible protein A Machinery gene
  FGK99_RS10215 - 1988188..1988376 (-) 189 WP_231147317.1 hypothetical protein -
  FGK99_RS09495 (NCTC4675_01929) - 1988472..1989044 (-) 573 WP_021321222.1 phospholipase A2 SlaB -
  FGK99_RS09500 (NCTC4675_01930) - 1989341..1990186 (+) 846 WP_012516446.1 helix-turn-helix domain-containing protein -
  FGK99_RS09505 (NCTC4675_01931) - 1990631..1991182 (-) 552 WP_038674690.1 DNA-3-methyladenine glycosylase I -
  FGK99_RS09510 (NCTC4675_01932) ruvA 1991192..1991788 (-) 597 WP_014623644.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46053.75 Da        Isoelectric Point: 5.5562

>NTDB_id=1127209 FGK99_RS09485 WP_138119896.1 1986231..1987502(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLRKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1127209 FGK99_RS09485 WP_138119896.1 1986231..1987502(-) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTAAGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAAGCTGCTAGGACACCAAATAATCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCACGCCAGTCTATACTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCCACCATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCACG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGCAAGACGATAACAGCAGCTGAAAGCTTGACAGCAGGACTGTTTCAAGCCC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.449

100

0.704
  cinA Streptococcus mitis NCTC 12261

69.784

98.582

0.688
  cinA Streptococcus mitis SK321

69.784

98.582

0.688
  cinA Streptococcus pneumoniae TIGR4

69.305

98.582

0.683
  cinA Streptococcus pneumoniae Rx1

69.305

98.582

0.683
  cinA Streptococcus pneumoniae R6

69.305

98.582

0.683
  cinA Streptococcus pneumoniae D39

69.065

98.582

0.681
  cinA Streptococcus suis isolate S10

53.699

99.054

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

46.89

98.818

0.463

Multiple sequence alignment