Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGK95_RS10020 Genome accession   NZ_LR590625
Coordinates   2018443..2019714 (-) Length   423 a.a.
NCBI ID   WP_093999150.1    Uniprot ID   -
Organism   Streptococcus canis strain B700072     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2013443..2024714
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK95_RS11020 - 2015090..2015215 (-) 126 WP_257865518.1 hypothetical protein -
  FGK95_RS09995 (SAMEA5186854_02008) - 2015293..2015598 (-) 306 WP_003045716.1 DUF1292 domain-containing protein -
  FGK95_RS10000 (SAMEA5186854_02009) ruvX 2015609..2016028 (-) 420 WP_039994721.1 Holliday junction resolvase RuvX -
  FGK95_RS10005 (SAMEA5186854_02010) - 2016025..2016294 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  FGK95_RS10010 (SAMEA5186854_02011) spx 2016406..2016804 (-) 399 WP_093999148.1 transcriptional regulator Spx -
  FGK95_RS10015 (SAMEA5186854_02012) recA 2017201..2018337 (-) 1137 WP_093999149.1 recombinase RecA Machinery gene
  FGK95_RS10020 (SAMEA5186854_02013) cinA 2018443..2019714 (-) 1272 WP_093999150.1 competence/damage-inducible protein A Machinery gene
  FGK95_RS11025 - 2019831..2019989 (-) 159 WP_223824822.1 VOC family protein -
  FGK95_RS10030 (SAMEA5186854_02015) - 2020187..2020759 (-) 573 WP_003045731.1 DNA-3-methyladenine glycosylase I -
  FGK95_RS10035 (SAMEA5186854_02016) ruvA 2020769..2021365 (-) 597 WP_003045733.1 Holliday junction branch migration protein RuvA -
  FGK95_RS10040 (SAMEA5186854_02017) - 2021349..2022587 (-) 1239 WP_003045734.1 MDR family MFS transporter -
  FGK95_RS10045 (SAMEA5186854_02018) mutL 2022598..2024580 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45899.59 Da        Isoelectric Point: 5.5559

>NTDB_id=1127131 FGK95_RS10020 WP_093999150.1 2018443..2019714(-) (cinA) [Streptococcus canis strain B700072]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIAIASQRSDLVILCGGLGPTEDDLTKQT
LAKFLKKDLVFDAQASQKLDDFFASRKQSSRTPNNERQAQLIAGSRPLQNKTGLAVGGLITVDDVTYVVLPGPPSELKPM
VNQELVPFLAHQSSKLYSKVLRFFGIGESQLVTILSDFIENQTDPTIAPYAKTGEVTLRLSTKAKNQTLADKKLAQLEAQ
LLSQKTPDNQPLSDFLYGYGEDNSLARETFELLIKNDKTITAAESLTAGLFQSTLANFSGASQVFNGGFVTYSMEEKAKM
LDIPLEDLKSYGVVSAYTAEKMAGQARLLTGADIGVSLTGVAGPDMLENQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPKNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1127131 FGK95_RS10020 WP_093999150.1 2018443..2019714(-) (cinA) [Streptococcus canis strain B700072]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCCCAATTTTTGTCGGA
GAAAATGGCAGAGCTAGGCATTGATGTCTATTTCCAGACAGCAGTTGGTGATAATGAAGAGCGTCTACTTTCTGTGATTG
CTATTGCTAGTCAACGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGACCTACCGAAGATGATTTAACCAAGCAAACC
CTAGCAAAATTTTTGAAGAAAGATTTGGTTTTTGATGCTCAAGCGAGTCAAAAACTAGATGACTTTTTTGCCAGTCGTAA
GCAGTCATCTCGAACACCAAATAATGAGAGGCAGGCACAACTGATTGCTGGATCAAGACCTTTACAAAATAAGACAGGGT
TGGCAGTTGGTGGTTTGATTACGGTTGATGATGTGACTTACGTTGTTTTACCGGGTCCTCCTAGTGAACTAAAGCCTATG
GTTAATCAGGAATTAGTACCTTTTCTGGCGCATCAGTCTAGCAAACTTTATTCGAAGGTTTTACGCTTTTTTGGGATTGG
CGAGAGTCAATTAGTAACGATTTTATCAGATTTTATTGAAAATCAGACTGATCCCACTATTGCTCCTTATGCTAAGACAG
GGGAGGTCACTCTTCGCTTATCAACAAAAGCTAAGAACCAGACTTTAGCAGATAAGAAACTAGCCCAATTAGAAGCTCAG
TTATTGTCCCAAAAAACTCCTGACAATCAGCCTTTATCAGATTTTCTTTATGGCTATGGAGAGGATAATTCCTTGGCGCG
TGAGACATTTGAGCTCTTAATAAAAAATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAATTTTTCAGGAGCTTCCCAAGTATTCAATGGAGGTTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGATATTCCTTTAGAAGATTTGAAATCATATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGGACAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTGAGTTTAACAGGTGTTGCTGGGCCAGATATGTTGGAGAACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATTGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTAAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

71.703

98.582

0.707
  cinA Streptococcus mitis NCTC 12261

71.223

98.582

0.702
  cinA Streptococcus pneumoniae TIGR4

70.743

98.582

0.697
  cinA Streptococcus pneumoniae Rx1

70.743

98.582

0.697
  cinA Streptococcus pneumoniae R6

70.743

98.582

0.697
  cinA Streptococcus pneumoniae D39

70.504

98.582

0.695
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

98.818

0.452

Multiple sequence alignment