Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FGK94_RS06695 Genome accession   NZ_LR590471
Coordinates   1422488..1423759 (+) Length   423 a.a.
NCBI ID   WP_043030240.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11854     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1417488..1428759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK94_RS06670 (NCTC11854_01366) ruvA 1418204..1418800 (+) 597 WP_015898664.1 Holliday junction branch migration protein RuvA -
  FGK94_RS06675 (NCTC11854_01367) - 1418810..1419361 (+) 552 WP_042671448.1 DNA-3-methyladenine glycosylase I -
  FGK94_RS06680 (NCTC11854_01368) - 1419806..1420649 (-) 844 Protein_1291 helix-turn-helix domain-containing protein -
  FGK94_RS06685 (NCTC11854_01370) - 1420946..1421518 (+) 573 WP_043030241.1 phosphlipase A2 SlaA -
  FGK94_RS06690 (NCTC11854_01371) - 1421512..1421802 (+) 291 WP_043026774.1 hypothetical protein -
  FGK94_RS06695 (NCTC11854_01372) cinA 1422488..1423759 (+) 1272 WP_043030240.1 competence/damage-inducible protein A Machinery gene
  FGK94_RS06700 (NCTC11854_01373) recA 1423853..1424989 (+) 1137 WP_012678688.1 recombinase RecA Machinery gene
  FGK94_RS06705 (NCTC11854_01374) spx 1425365..1425763 (+) 399 WP_012516440.1 transcriptional regulator Spx -
  FGK94_RS06710 (NCTC11854_01375) - 1425876..1426145 (+) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  FGK94_RS06715 (NCTC11854_01376) ruvX 1426142..1426561 (+) 420 WP_012678687.1 Holliday junction resolvase RuvX -
  FGK94_RS06720 (NCTC11854_01377) - 1426571..1426870 (+) 300 WP_021321220.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45808.52 Da        Isoelectric Point: 5.8304

>NTDB_id=1126886 FGK94_RS06695 WP_043030240.1 1422488..1423759(+) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTLRLSTKADNQALADERLNRLEAQ
LLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIAALYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1126886 FGK94_RS06695 WP_043030240.1 1422488..1423759(+) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC11854]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTTTATCAGA
AAAAATGGCGGAGCTTGGTATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCAGGCTGCTAGGACACCAAATAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTATTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGGTTAATAACTGTAGATAGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGCTAAAGCCTATG
GTAAAAAATGAGCTGGTGCCCCTTCTTTCAGCTAGTCATGCCAGTCTATATTCAAGAGTGCTGCGTTTTTTTGGCATTGG
TGAAAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGCATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGACAACCAAGCATTAGCTGATGAAAGGCTGAATCGACTAGAGGCGCAG
CTCTTATCCATAAGAACTGTAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCGCG
TGAGACCTTTGAGTTATTGAAGCGAAGTGGTAAGACGATAACAGCAGCTGAAAGCTTAACAGCAGGACTGTTTCAGGCTC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAACAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGCCCAGAGGCACTCGAGGGACAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTTATAGGAGGCCGTAGCCGTTTGGACGTG
CGGTATATTGCTGCCCTATATGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.686

100

0.707
  cinA Streptococcus mitis NCTC 12261

70.504

98.582

0.695
  cinA Streptococcus mitis SK321

70.264

98.582

0.693
  cinA Streptococcus pneumoniae TIGR4

70.024

98.582

0.69
  cinA Streptococcus pneumoniae Rx1

70.024

98.582

0.69
  cinA Streptococcus pneumoniae R6

70.024

98.582

0.69
  cinA Streptococcus pneumoniae D39

69.784

98.582

0.688
  cinA Streptococcus suis isolate S10

53.938

99.054

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

47.847

98.818

0.473

Multiple sequence alignment