Detailed information NTG1126549

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: E0F34_RS04650
• Genome accession: NZ_LR536843
• Coordinates: 855495..856136 (+)
• Length: 213 a.a.
• NCBI ID: WP_044814472.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 850495..861136

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS04605 (SAMEA104035599_00874)	-	850979..851194 (+)	216	WP_001232082.1	YozE family protein	-
E0F34_RS04610 (SAMEA104035599_00875)	-	851280..852248 (+)	969	WP_000658183.1	PhoH family protein	-
E0F34_RS04620 (SAMEA104035599_00876)	-	852441..852941 (+)	501	WP_000566989.1	GNAT family N-acetyltransferase	-
E0F34_RS04625	-	852944..853269 (+)	326	Protein_876	TfoX/Sxy family protein	-
E0F34_RS11870	ald	853570..854681 (-)	1112	Protein_877	alanine dehydrogenase	-
E0F34_RS04645 (SAMEA104035599_00880)	-	854858..855427 (+)	570	WP_044814470.1	GNAT family N-acetyltransferase	-
E0F34_RS04650 (SAMEA104035599_00881)	comEA/celA/cilE	855495..856136 (+)	642	WP_044814472.1	helix-hairpin-helix domain-containing protein	Machinery gene
E0F34_RS04655 (SAMEA104035599_00882)	comEC/celB	856120..858360 (+)	2241	WP_061384506.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
E0F34_RS04660	-	858539..858727 (+)	189	WP_044812623.1	hypothetical protein	-
E0F34_RS04665 (SAMEA104035599_00883)	-	858760..859347 (+)	588	WP_000939884.1	ATP-binding cassette domain-containing protein	-
E0F34_RS04670 (SAMEA104035599_00884)	-	859351..860532 (+)	1182	WP_000655951.1	membrane protein	-

Sequence

Protein

• Length: 213 a.a.
• Molecular weight: 22764.96 Da
• Isoelectric Point: 6.0542

>NTDB_id=1126549 E0F34_RS04650 WP_044814472.1 855495..856136(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTEKEVNKEEPLEQDLITVDVKGAVK
SPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESASQQAGSGAPSSTSKDKKVNLNKASLE
ELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 642 bp

>NTDB_id=1126549 E0F34_RS04650 WP_044814472.1 855495..856136(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAGGAAACGAATTTGCAGGCAGAAGTTGCAGCTGTTTCCAAGGATT
CATCGACCGAAAAGGAAGTGAACAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGTGCTGTCAAA
TCGCCAGGGATTTATGACTTGCCTGTAGGTAGTAGAGTCAATGATGCCGTGCAGAAAGCAGGTGGCTTGACAGAACAAGC
AGATAGTAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGACGAGGCTCTGGTTTACGTTCCCACTAAGGGAGAAGAATCAG
CTAGTCAACAGGCAGGTTCTGGAGCGCCTTCTTCAACAAGCAAGGACAAGAAGGTCAATCTCAACAAGGCCAGTCTGGAA
GAACTCAAGCAGGTCAAGGGTCTGGGAGGAAAACGAGCTCAAGACATTATCGACCATCGTGAAACAAATGGGAAATTTAA
GTCGGTTGATGAACTCAAGAAGGTATCTGGAATTGGTGCAAAGACCATAGAAAAGCTTAAAGATTATGTTACAGTGGATT
AA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (149-211)

• SLBB domain (SLBB) (73-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	94.444	100	0.958
comEA/celA/cilE	Streptococcus mitis NCTC 12261	93.981	100	0.953
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.939
comEA/celA/cilE	Streptococcus pneumoniae Rx1	90.278	100	0.915
comEA/celA/cilE	Streptococcus pneumoniae D39	90.278	100	0.915
comEA/celA/cilE	Streptococcus pneumoniae R6	90.278	100	0.915
comEA	Lactococcus lactis subsp. cremoris KW2	43.75	100	0.46
comEA	Bacillus subtilis subsp. subtilis str. 168	42.246	87.793	0.371
comEA	Latilactobacillus sakei subsp. sakei 23K	33.478	100	0.361