Detailed information NTG1126550

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: E0F34_RS04655
• Genome accession: NZ_LR536843
• Coordinates: 856120..858360 (+)
• Length: 746 a.a.
• NCBI ID: WP_061384506.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 851120..863360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F34_RS04610 (SAMEA104035599_00875)	-	851280..852248 (+)	969	WP_000658183.1	PhoH family protein	-
E0F34_RS04620 (SAMEA104035599_00876)	-	852441..852941 (+)	501	WP_000566989.1	GNAT family N-acetyltransferase	-
E0F34_RS04625	-	852944..853269 (+)	326	Protein_876	TfoX/Sxy family protein	-
E0F34_RS11870	ald	853570..854681 (-)	1112	Protein_877	alanine dehydrogenase	-
E0F34_RS04645 (SAMEA104035599_00880)	-	854858..855427 (+)	570	WP_044814470.1	GNAT family N-acetyltransferase	-
E0F34_RS04650 (SAMEA104035599_00881)	comEA/celA/cilE	855495..856136 (+)	642	WP_044814472.1	helix-hairpin-helix domain-containing protein	Machinery gene
E0F34_RS04655 (SAMEA104035599_00882)	comEC/celB	856120..858360 (+)	2241	WP_061384506.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
E0F34_RS04660	-	858539..858727 (+)	189	WP_044812623.1	hypothetical protein	-
E0F34_RS04665 (SAMEA104035599_00883)	-	858760..859347 (+)	588	WP_000939884.1	ATP-binding cassette domain-containing protein	-
E0F34_RS04670 (SAMEA104035599_00884)	-	859351..860532 (+)	1182	WP_000655951.1	membrane protein	-
E0F34_RS04675	infC	860839..861369 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
E0F34_RS04680 (SAMEA104035599_00886)	rpmI	861402..861602 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
E0F34_RS04685 (SAMEA104035599_00887)	rplT	861654..862013 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
E0F34_RS04690 (SAMEA104035599_00888)	-	862071..862451 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84698.36 Da
• Isoelectric Point: 9.3594

>NTDB_id=1126550 E0F34_RS04655 WP_061384506.1 856120..858360(+) (comEC/celB) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
MLQWIKNFPIPLIYMSFLLLWLYYAIFSVSYFALLGFVFLLVCLFIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQN
LVDSVERVRILPDTIKVNGDSLSFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFALSFLYPVIQLNFIFEWLEGMIRLVSKVASRPLVFGQPNAWLLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDIGQGESIFLRDMTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRNVTAGENLPIFGSQLEVLSPRKIGDGDHEDSLVLYGKL
LDKYFLFTGNLEEKGERDLLKHYPDLKVNVLKASQQGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1126550 E0F34_RS04655 WP_061384506.1 856120..858360(+) (comEC/celB) [Streptococcus pneumoniae strain GPSC55 substr. ST3774 isolate b04a6400-1f66-11e7-b93e-3c4a9275d6c8]
ATGTTACAGTGGATTAAAAATTTCCCCATTCCCCTGATTTACATGAGCTTTCTGTTACTTTGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGTTTTGTTTTTCTGCTAGTCTGCCTCTTTATCCAATTTCCTTGGAAATCAGCAG
GTAAAGTTCTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAACTTGGCAACAGAGTCAAGTGAGTCAAAAT
CTGGTGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTATTAAGGTTAACGGTGACAGTCTGTCCTTTCGTGGTAA
GTCTGATGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACTGACC
TTCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGGCTAT
CTGAAGACTCAGGGAATTTACCAGACACTCAATATTAAAAGAATCCAGTCACTCCAAAAGGTTGGCAGTTGGGATATAGG
TGAAAACCTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGATGCACTTCCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTAGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTTTAGGAATTATTCACCTT
TTTGCCTTGTCAGGTATGCAGGTAGGGTTTTTCATGGACGGATTTAAGAAACTACTTTTACGATTGGGCTTGACACAAGA
AAAGTTGAAGTGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTGTCCTTCTATTTTGCGG
AATTTCAACCTTGGTCCATCCTCTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGCCCTTTCCTTTCTATATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGAATGATTCGCTTGGT
ATCAAAGGTGGCAAGTAGGCCTCTAGTCTTTGGACAACCCAATGCATGGCTTTTAATCTTGTTGTTAATTTCCTTGGCTT
TAGTATATGATTTGAGAAAAAATATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATATTGGGCAAGGAGAAAGTATTTTCCTACGGGATATGACTGGTAAAAC
CATTCTCATAGATGTCGGTGGCAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGTAACTCAAACCAAGGTGCGCAATGTGACAGCAGGAGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGAGATCATGAAGATTCCCTTGTTCTATACGGGAAACTC
TTGGATAAATACTTTCTCTTCACAGGAAATTTGGAGGAGAAAGGAGAGAGGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACAAGGAAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-633)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	94.102	100	0.941
comEC/celB	Streptococcus pneumoniae D39	93.968	100	0.94
comEC/celB	Streptococcus pneumoniae R6	93.968	100	0.94
comEC/celB	Streptococcus pneumoniae Rx1	93.968	100	0.94
comEC/celB	Streptococcus mitis SK321	91.957	100	0.92
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44