Detailed information NTG1126182

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: E0F39_RS04895
• Genome accession: NZ_LR216060
• Coordinates: 904049..904699 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387330.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 899049..909699

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F39_RS04860 (SAMEA3713867_00911)	-	899521..899736 (+)	216	WP_001232081.1	YozE family protein	-
E0F39_RS04865 (SAMEA3713867_00912)	-	899822..900790 (+)	969	WP_000658183.1	PhoH family protein	-
E0F39_RS04875 (SAMEA3713867_00913)	-	900983..901495 (+)	513	WP_001864628.1	GNAT family N-acetyltransferase	-
E0F39_RS04880	-	901498..901823 (+)	326	Protein_927	TfoX/Sxy family protein	-
E0F39_RS12760	ald	902124..903235 (-)	1112	Protein_928	alanine dehydrogenase	-
E0F39_RS04890 (SAMEA3713867_00917)	-	903412..903981 (+)	570	WP_001864630.1	GNAT family N-acetyltransferase	-
E0F39_RS04895 (SAMEA3713867_00918)	comEA/celA/cilE	904049..904699 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
E0F39_RS04900 (SAMEA3713867_00919)	comEC/celB	904683..906923 (+)	2241	WP_001864631.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
E0F39_RS04905	-	907102..907290 (+)	189	WP_001809102.1	hypothetical protein	-
E0F39_RS04910 (SAMEA3713867_00920)	-	907322..907909 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
E0F39_RS04915 (SAMEA3713867_00921)	-	907913..909094 (+)	1182	WP_000655952.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23229.65 Da
• Isoelectric Point: 5.5171

>NTDB_id=1126182 E0F39_RS04895 WP_000387330.1 904049..904699(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=1126182 E0F39_RS04895 WP_000387330.1 904049..904699(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCT
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae D39	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae R6	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	97.222	100	0.972
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361