Detailed information NTG1126183

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: E0F39_RS04900
• Genome accession: NZ_LR216060
• Coordinates: 904683..906923 (+)
• Length: 746 a.a.
• NCBI ID: WP_001864631.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 899683..911923

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F39_RS04865 (SAMEA3713867_00912)	-	899822..900790 (+)	969	WP_000658183.1	PhoH family protein	-
E0F39_RS04875 (SAMEA3713867_00913)	-	900983..901495 (+)	513	WP_001864628.1	GNAT family N-acetyltransferase	-
E0F39_RS04880	-	901498..901823 (+)	326	Protein_927	TfoX/Sxy family protein	-
E0F39_RS12760	ald	902124..903235 (-)	1112	Protein_928	alanine dehydrogenase	-
E0F39_RS04890 (SAMEA3713867_00917)	-	903412..903981 (+)	570	WP_001864630.1	GNAT family N-acetyltransferase	-
E0F39_RS04895 (SAMEA3713867_00918)	comEA/celA/cilE	904049..904699 (+)	651	WP_000387330.1	ComEA family DNA-binding protein	Machinery gene
E0F39_RS04900 (SAMEA3713867_00919)	comEC/celB	904683..906923 (+)	2241	WP_001864631.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
E0F39_RS04905	-	907102..907290 (+)	189	WP_001809102.1	hypothetical protein	-
E0F39_RS04910 (SAMEA3713867_00920)	-	907322..907909 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
E0F39_RS04915 (SAMEA3713867_00921)	-	907913..909094 (+)	1182	WP_000655952.1	membrane protein	-
E0F39_RS04920 (SAMEA3713867_00922)	infC	909401..909931 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
E0F39_RS04925 (SAMEA3713867_00923)	rpmI	909964..910164 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
E0F39_RS04930 (SAMEA3713867_00924)	rplT	910216..910575 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
E0F39_RS04935 (SAMEA3713867_00925)	-	910633..911013 (+)	381	WP_000157153.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84540.22 Da
• Isoelectric Point: 9.8481

>NTDB_id=1126183 E0F39_RS04900 WP_001864631.1 904683..906923(+) (comEC/celB) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLNTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIKKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLSEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLKVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1126183 E0F39_RS04900 WP_001864631.1 904683..906923(+) (comEC/celB) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGAACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCAAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGCATGTTGGAGATTTGTCAGAGATGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGATAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAAAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	99.196	100	0.992
comEC/celB	Streptococcus pneumoniae Rx1	97.855	100	0.979
comEC/celB	Streptococcus pneumoniae D39	97.855	100	0.979
comEC/celB	Streptococcus pneumoniae R6	97.855	100	0.979
comEC/celB	Streptococcus mitis SK321	92.225	100	0.922
comEC/celB	Streptococcus mitis NCTC 12261	91.678	99.866	0.916
comEC	Lactococcus lactis subsp. cremoris KW2	44.399	99.33	0.441