Detailed information NTG1126099

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: E0F32_RS02520
• Genome accession: NZ_LR216050
• Coordinates: 446428..448071 (+)
• Length: 547 a.a.
• NCBI ID: WP_078133412.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 441428..453071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F32_RS02460 (SAMEA3431333_00459)	-	441908..442291 (-)	384	WP_000877381.1	hypothetical protein	-
E0F32_RS12215 (SAMEA3431333_00460)	-	442920..443278 (-)	359	Protein_467	immunity protein	-
E0F32_RS02480	-	443759..443878 (-)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
E0F32_RS12350	-	443881..443946 (-)	66	Protein_469	ComC/BlpC family peptide pheromone/bacteriocin	-
E0F32_RS02485	cipB	443982..444131 (-)	150	WP_001809846.1	bacteriocin-like peptide BlpO	Regulator
E0F32_RS02495 (SAMEA3431333_00462)	blpK	444375..444623 (-)	249	WP_000379965.1	bacteriocin-like peptide BlpK	-
E0F32_RS02500 (SAMEA3431333_00463)	blpJ	444692..444961 (-)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
E0F32_RS02510 (SAMEA3431333_00464)	blpI	445428..445625 (-)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
E0F32_RS12220 (SAMEA3431333_00465)	comA/nlmT	445914..446501 (+)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
E0F32_RS02520 (SAMEA3431333_00466)	comA/nlmT	446428..448071 (+)	1644	WP_078133412.1	peptide cleavage/export ABC transporter	Regulator
E0F32_RS02525 (SAMEA3431333_00467)	-	448082..449443 (+)	1362	WP_001069060.1	bacteriocin secretion accessory protein	-
E0F32_RS02530 (SAMEA3431333_00468)	blpC	449500..449628 (+)	129	WP_000358815.1	quorum-sensing system pheromone BlpC	-
E0F32_RS02535 (SAMEA3431333_00469)	-	449699..451039 (-)	1341	WP_001017642.1	sensor histidine kinase	-
E0F32_RS02540 (SAMEA3431333_00470)	comE/blpR	451053..451790 (-)	738	WP_001219120.1	response regulator transcription factor	Regulator
E0F32_RS02545 (SAMEA3431333_00471)	-	451795..452133 (-)	339	WP_000876675.1	LytTR family DNA-binding domain-containing protein	-
E0F32_RS02550 (SAMEA3431333_00472)	-	452409..452738 (+)	330	WP_000132572.1	hypothetical protein	-

Sequence

Protein

• Length: 547 a.a.
• Molecular weight: 61671.67 Da
• Isoelectric Point: 6.5088

>NTDB_id=1126099 E0F32_RS02520 WP_078133412.1 446428..448071(+) (comA/nlmT) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLVQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1644 bp

>NTDB_id=1126099 E0F32_RS02520 WP_078133412.1 446428..448071(+) (comA/nlmT) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGTACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (330-479)

• ABC transporter transmembrane region (ABC_membrane) (2-268)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.894	99.817	0.728
comA	Streptococcus mitis NCTC 12261	67.824	100	0.678
comA	Streptococcus pneumoniae D39	67.459	100	0.675
comA	Streptococcus pneumoniae R6	67.459	100	0.675
comA	Streptococcus pneumoniae Rx1	67.459	100	0.675
comA	Streptococcus mitis SK321	67.276	100	0.673
comA	Streptococcus gordonii str. Challis substr. CH1	67.153	100	0.673
comA	Streptococcus pneumoniae TIGR4	67.093	100	0.671