Detailed information NTG1125305

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: EQB43_RS14125
• Genome accession: NZ_LR135384
• Coordinates: 2727185..2728426 (-)
• Length: 413 a.a.
• NCBI ID: WP_002296026.1
• Uniprot ID: A0AAV3GRJ1
• Organism: Enterococcus faecium isolate E7933
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Genomic Context

Location: 2722185..2733426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQB43_RS14110	proC	2723175..2723981 (+)	807	WP_002296027.1	pyrroline-5-carboxylate reductase	-
EQB43_RS14115	rny	2724060..2725616 (-)	1557	WP_002287336.1	ribonuclease Y	-
EQB43_RS14120	recA	2726027..2727076 (-)	1050	WP_002287328.1	recombinase RecA	Machinery gene
EQB43_RS14125	cinA	2727185..2728426 (-)	1242	WP_002296026.1	competence/damage-inducible protein A	Machinery gene
EQB43_RS14130	pgsA	2728666..2729244 (-)	579	WP_002296025.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	-
EQB43_RS14140	-	2729453..2730376 (-)	924	WP_002287423.1	RodZ domain-containing protein	-
EQB43_RS14145	yfmH	2731114..2732400 (-)	1287	WP_002287425.1	EF-P 5-aminopentanol modification-associated protein YfmH	-

Sequence

Protein

• Length: 413 a.a.
• Molecular weight: 45415.76 Da
• Isoelectric Point: 4.6507

>NTDB_id=1125305 EQB43_RS14125 WP_002296026.1 2727185..2728426(-) (cinA) [Enterococcus faecium isolate E7933]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide

• Length: 1242 bp

>NTDB_id=1125305 EQB43_RS14125 WP_002296026.1 2727185..2728426(-) (cinA) [Enterococcus faecium isolate E7933]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

• Competence-damaged protein (CinA) (258-410)

• Damage-inducible protein CinA KH domain (CinA_KH) (180-253)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mitis SK321	51.19	100	0.521
cinA	Streptococcus mutans UA159	51.566	100	0.518
cinA	Streptococcus pneumoniae TIGR4	50.952	100	0.518
cinA	Streptococcus pneumoniae D39	50.714	100	0.516
cinA	Streptococcus pneumoniae R6	50.714	100	0.516
cinA	Streptococcus pneumoniae Rx1	50.714	100	0.516
cinA	Streptococcus mitis NCTC 12261	50.714	100	0.516
cinA	Bacillus subtilis subsp. subtilis str. 168	47.573	99.758	0.475
cinA	Streptococcus suis isolate S10	41.787	100	0.419