Detailed information NTG1124396

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: EL353_RS12860
• Genome accession: NZ_LR135181
• Coordinates: 2511315..2512556 (-)
• Length: 413 a.a.
• NCBI ID: WP_002296026.1
• Uniprot ID: A0AAV3GRJ1
• Organism: Enterococcus faecium isolate E1774
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Genomic Context

Location: 2506315..2517556

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL353_RS12845	proC	2507305..2508111 (+)	807	WP_002296027.1	pyrroline-5-carboxylate reductase	-
EL353_RS12850	rny	2508190..2509746 (-)	1557	WP_002287336.1	ribonuclease Y	-
EL353_RS12855	recA	2510157..2511206 (-)	1050	WP_002287328.1	recombinase RecA	Machinery gene
EL353_RS12860	cinA	2511315..2512556 (-)	1242	WP_002296026.1	competence/damage-inducible protein A	Machinery gene
EL353_RS12865	pgsA	2512796..2513374 (-)	579	WP_002296025.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	-
EL353_RS12875	-	2513583..2514506 (-)	924	WP_002287423.1	RodZ domain-containing protein	-
EL353_RS12880	yfmH	2515245..2516531 (-)	1287	WP_002287425.1	EF-P 5-aminopentanol modification-associated protein YfmH	-

Sequence

Protein

• Length: 413 a.a.
• Molecular weight: 45415.76 Da
• Isoelectric Point: 4.6507

>NTDB_id=1124396 EL353_RS12860 WP_002296026.1 2511315..2512556(-) (cinA) [Enterococcus faecium isolate E1774]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLAYFETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide

• Length: 1242 bp

>NTDB_id=1124396 EL353_RS12860 WP_002296026.1 2511315..2512556(-) (cinA) [Enterococcus faecium isolate E1774]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGCATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATTATCGAAGGCGGGGTTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAGACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

• Competence-damaged protein (CinA) (258-410)

• Damage-inducible protein CinA KH domain (CinA_KH) (180-253)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mitis SK321	51.19	100	0.521
cinA	Streptococcus mutans UA159	51.566	100	0.518
cinA	Streptococcus pneumoniae TIGR4	50.952	100	0.518
cinA	Streptococcus pneumoniae D39	50.714	100	0.516
cinA	Streptococcus pneumoniae R6	50.714	100	0.516
cinA	Streptococcus pneumoniae Rx1	50.714	100	0.516
cinA	Streptococcus mitis NCTC 12261	50.714	100	0.516
cinA	Bacillus subtilis subsp. subtilis str. 168	47.573	99.758	0.475
cinA	Streptococcus suis isolate S10	41.787	100	0.419