Detailed information NTG1124285

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: EL345_RS11695
• Genome accession: NZ_LR135170
• Coordinates: 2293114..2294355 (-)
• Length: 413 a.a.
• NCBI ID: WP_002298209.1
• Uniprot ID: -
• Organism: Enterococcus faecium isolate E4227
• Function: facilitate localization of RecA (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2294414..2295322	2293114..2294355	flank	59

Gene organization within MGE regions

Location: 2293114..2295322

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL345_RS11695	cinA	2293114..2294355 (-)	1242	WP_002298209.1	competence/damage-inducible protein A	Machinery gene
EL345_RS11700	-	2294414..2295322 (-)	909	WP_061573572.1	IS982-like element ISEfm1 family transposase	-

Sequence

Protein

• Length: 413 a.a.
• Molecular weight: 45457.84 Da
• Isoelectric Point: 4.6507

>NTDB_id=1124285 EL345_RS11695 WP_002298209.1 2293114..2294355(-) (cinA) [Enterococcus faecium isolate E4227]
MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGDNQQRLEELIALAETRSELILLCGGLGPTEDDLTKEA
TAAHLGKSLIQNTEGYKKLLVYFETTHRKMTKNNLQQSQIIEGGIPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTNDVQAGNQALLALE
EKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVTAAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDP
ELLAEYGTVSKECVEQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRAAIRYNAVM
QGFDLLRKQLLRK

Nucleotide

• Length: 1242 bp

>NTDB_id=1124285 EL345_RS11695 WP_002298209.1 2293114..2294355(-) (cinA) [Enterococcus faecium isolate E4227]
ATGAAAGCAGAAATAATAGCTGTCGGAACAGAACTTTTACTAGGACAAGTCGTGAATACGAATGCCACTTTCTTGTCAGA
ACAGCTAGCTGATCTAGGTATCGAAGTTTATTATCAAACAGTTGTAGGAGATAATCAGCAGCGTTTAGAAGAGTTGATTG
CTCTAGCTGAAACAAGAAGTGAACTCATACTCTTATGTGGCGGATTAGGACCGACAGAAGATGACCTGACAAAAGAAGCA
ACTGCGGCTCACCTCGGTAAGTCTCTCATACAAAATACGGAAGGATACAAAAAATTATTGGTATATTTTGAAACAACCCA
TCGAAAAATGACCAAAAACAATCTGCAACAGTCCCAGATCATCGAAGGCGGGATTCCTCTACCAAATCGTACAGGGCTTG
CTTTAGGGACTTTTTATCAAACAGATACACATGCGTATATCCTTCTTCCCGGTCCGCCTAATGAGTTGAAACCAATGTTT
GTGGAACAAGTACGTCCTTTACTAGAGGAACGTTTTCCTTCTGAAGAAAAACTAATTTCTAAAGTTTTGCGCTTTTATGG
GATTGGTGAATCGCGACTGGTCACTGAGCTAAAAGATCTGATTGAAACACAGATCAATCCAACGATCGCACCATATGCCA
AACCAAATGAAGTGACATTACGACTGACAGTGAAAACAAATGATGTTCAGGCAGGGAATCAAGCTCTTTTAGCATTAGAA
GAAAAAATCCAAGAACGAGTAGGGGAATATTTTTATGGATACGGCGATGATAATTCGCTAGCAAAAGTCGTAGTGGAACT
ACTGAAAGAAAACAAGCAGACTGTAACAGCAGCGGAAAGTTTGACAGCCGGCGCCTTCCAAGCCGCATTAGGCGACATTG
CTGGTGTATCTGAAGTATTTCCAGGCGGATTCGTTACCTACTCGCTCCAAACAAAAGCTGGTTTTCTGGAGATTGATCCG
GAGCTATTAGCAGAATATGGAACAGTCAGCAAAGAATGTGTGGAGCAGATGGCCATTCAAGCACGTGAGATAGCAAGAAC
AGATTACAGTGTAGCTTTCACCGGAGTGGCTGGACCGGACACGTTAGAAGGTCAATCTGCAGGAACAGTATGGATCGCTA
TTTCATCTAAAGACGGCGTGGTTTCGGAAAAATATCACTTTGCCAGAGATCGTGCTGCTATCAGATATAATGCGGTTATG
CAAGGATTTGATCTTTTGAGAAAACAGCTTTTAAGAAAATGA

Domains

Predicted by InterproScan.

• Damage-inducible protein CinA KH domain (CinA_KH) (180-253)

• Competence-damaged protein (CinA) (258-410)

• Probable molybdopterin binding domain (MoCF_biosynth) (5-169)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus mitis SK321	51.429	100	0.523
cinA	Streptococcus pneumoniae TIGR4	51.19	100	0.521
cinA	Streptococcus mitis NCTC 12261	51.19	100	0.521
cinA	Streptococcus mutans UA159	51.566	100	0.518
cinA	Streptococcus pneumoniae R6	50.952	100	0.518
cinA	Streptococcus pneumoniae Rx1	50.952	100	0.518
cinA	Streptococcus pneumoniae D39	50.952	100	0.518
cinA	Bacillus subtilis subsp. subtilis str. 168	47.573	99.758	0.475
cinA	Streptococcus suis isolate S10	41.787	100	0.419