Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL223_RS14830 Genome accession   NZ_LR134474
Coordinates   3051580..3052836 (-) Length   418 a.a.
NCBI ID   WP_126344610.1    Uniprot ID   -
Organism   Kurthia zopfii strain NCTC404     
Function   unknown (predicted from homology)   
Unclear

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3035667..3051437 3051580..3052836 flank 143


Gene organization within MGE regions


Location: 3035667..3052836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL223_RS14765 (NCTC404_03089) - 3035667..3036875 (-) 1209 WP_126344624.1 ISL3 family transposase -
  EL223_RS14770 (NCTC404_03091) - 3037212..3037487 (-) 276 WP_126344604.1 transposase -
  EL223_RS14775 (NCTC404_03092) - 3037617..3038912 (-) 1296 WP_115329356.1 ISL3 family transposase -
  EL223_RS14780 (NCTC404_03093) - 3039131..3040339 (-) 1209 WP_126344624.1 ISL3 family transposase -
  EL223_RS14785 (NCTC404_03094) - 3040562..3041599 (-) 1038 WP_126344606.1 ISL3 family transposase -
  EL223_RS14790 (NCTC404_03095) - 3041914..3042780 (-) 867 WP_109349288.1 2-oxoacid:ferredoxin oxidoreductase subunit beta -
  EL223_RS14795 (NCTC404_03096) - 3042781..3044529 (-) 1749 WP_109349287.1 2-oxoacid:acceptor oxidoreductase subunit alpha -
  EL223_RS14800 (NCTC404_03097) - 3044826..3045086 (+) 261 WP_126344608.1 hypothetical protein -
  EL223_RS14805 (NCTC404_03098) - 3045122..3045814 (+) 693 WP_109349285.1 hypothetical protein -
  EL223_RS14810 (NCTC404_03099) - 3045877..3046674 (-) 798 WP_109349284.1 TIGR00282 family metallophosphoesterase -
  EL223_RS14815 (NCTC404_03100) rny 3046732..3048288 (-) 1557 WP_109349283.1 ribonuclease Y -
  EL223_RS14820 (NCTC404_03101) - 3048875..3049948 (-) 1074 WP_232025920.1 ISL3 family transposase -
  EL223_RS15260 (NCTC404_03102) - 3049970..3050170 (-) 201 WP_232025922.1 hypothetical protein -
  EL223_RS14825 (NCTC404_03103) recA 3050376..3051437 (-) 1062 WP_109349282.1 recombinase RecA Machinery gene
  EL223_RS14830 (NCTC404_03104) cinA 3051580..3052836 (-) 1257 WP_126344610.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45536.34 Da        Isoelectric Point: 4.6938

>NTDB_id=1122963 EL223_RS14830 WP_126344610.1 3051580..3052836(-) (cinA) [Kurthia zopfii strain NCTC404]
MNAEIIAVGSELLLGQIANTNAKFISSQLSELGINVYYHTVVGDNPKRLVQAIEIAEKRADLIIFSGGLGPTKDDLTKET
IAKHLGRGMKEDLEAMNMIEAFFAKRNRPMTANNRKQALVIEGSEVLANENGMAPGMFIPLENSIVILLPGPPKELEPMF
QFEAKPKLAKLVSDGGLIVSHVLRFYGIGEAELEDRVQHIIDQQTNPTIAPLAGDGEVTLRITAKAASEEEAWSLITPTR
TELLEIVGDYLYGVNDDSLSSKLVNMLIENDLKISAAESLTAGLFQSELAAIEGVSQVLQGGMVTYTEEMKINQLGVPKE
IIDQYSVVSAECAASMAINIKEKFNADIGVSLTGAAGPGKHADQPVGTVWIGIAFRDDEPLTFELNLQGMRNTNRLRSVK
TAIYRLIQLLSEKGYRKI

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1122963 EL223_RS14830 WP_126344610.1 3051580..3052836(-) (cinA) [Kurthia zopfii strain NCTC404]
ATGAATGCAGAAATTATAGCAGTTGGTTCGGAACTACTTTTAGGGCAAATCGCTAATACGAACGCTAAATTTATTTCAAG
CCAACTATCAGAACTAGGCATTAATGTTTATTATCATACCGTTGTAGGTGATAATCCGAAACGTTTAGTACAAGCAATAG
AAATCGCTGAAAAAAGAGCAGATTTAATTATTTTCTCTGGTGGCTTGGGCCCGACGAAAGATGATTTAACGAAGGAAACA
ATTGCGAAGCATCTAGGTCGAGGTATGAAGGAAGATTTAGAGGCTATGAACATGATCGAAGCTTTCTTTGCAAAGAGAAA
TCGTCCAATGACGGCGAATAATCGTAAACAAGCACTCGTGATTGAAGGCTCAGAAGTTCTCGCAAACGAAAATGGCATGG
CTCCAGGTATGTTTATACCATTAGAGAACAGTATCGTCATTCTTTTACCAGGTCCGCCGAAAGAATTAGAGCCAATGTTC
CAATTCGAAGCGAAACCAAAGCTTGCAAAACTCGTATCAGATGGCGGTTTAATCGTTTCTCATGTCCTGCGTTTCTATGG
GATTGGTGAAGCGGAATTAGAAGATCGCGTACAACATATAATTGACCAACAGACGAATCCGACAATCGCACCTTTAGCTG
GAGATGGCGAAGTAACTTTACGTATTACTGCCAAAGCAGCAAGTGAAGAAGAAGCATGGTCACTGATCACGCCGACACGT
ACGGAATTACTTGAAATCGTTGGTGACTATTTATACGGTGTAAATGATGATTCTTTAAGTAGTAAATTAGTAAATATGTT
GATTGAAAATGATTTGAAGATTTCTGCAGCTGAAAGTCTGACTGCAGGGCTATTCCAATCTGAATTAGCCGCAATAGAAG
GTGTCAGTCAAGTATTACAAGGTGGCATGGTGACTTATACGGAAGAAATGAAAATCAATCAATTAGGCGTTCCGAAAGAA
ATTATTGATCAATATTCGGTTGTAAGTGCAGAATGTGCAGCTTCAATGGCCATTAATATAAAAGAAAAATTTAATGCAGA
CATAGGCGTTTCGTTAACAGGCGCTGCTGGACCAGGCAAACACGCAGATCAACCTGTTGGTACTGTGTGGATTGGGATTG
CATTCCGCGATGACGAACCACTAACTTTTGAACTTAATTTACAAGGTATGCGCAATACAAATCGACTAAGATCTGTAAAA
ACGGCTATATACCGATTGATCCAATTGCTATCAGAAAAAGGGTACCGTAAAATATAG

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(257-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Bacillus subtilis subsp. subtilis str. 168

54.501

98.325

0.536
  cinA Streptococcus mitis SK321

44.909

91.627

0.411
  cinA Streptococcus pneumoniae TIGR4

44.909

91.627

0.411
  cinA Streptococcus pneumoniae Rx1

44.909

91.627

0.411
  cinA Streptococcus pneumoniae R6

44.909

91.627

0.411
  cinA Streptococcus mutans UA159

45.503

90.431

0.411
  cinA Streptococcus mitis NCTC 12261

44.648

91.627

0.409
  cinA Streptococcus pneumoniae D39

44.648

91.627

0.409

Multiple sequence alignment