Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL136_RS09825 Genome accession   NZ_LR134317
Coordinates   2052154..2053425 (+) Length   423 a.a.
NCBI ID   WP_043039523.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2047154..2058425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS09800 (NCTC6180_02010) ruvA 2047869..2048465 (+) 597 WP_012678694.1 Holliday junction branch migration protein RuvA -
  EL136_RS09805 (NCTC6180_02011) - 2048475..2049026 (+) 552 WP_043026779.1 DNA-3-methyladenine glycosylase I -
  EL136_RS09810 (NCTC6180_02012) - 2049470..2050315 (-) 846 WP_012678692.1 helix-turn-helix domain-containing protein -
  EL136_RS09815 (NCTC6180_02013) - 2050612..2051184 (+) 573 WP_021321222.1 phospholipase A2 SlaB -
  EL136_RS09820 (NCTC6180_02014) - 2051178..2051468 (+) 291 WP_012516443.1 hypothetical protein -
  EL136_RS09825 (NCTC6180_02015) cinA 2052154..2053425 (+) 1272 WP_043039523.1 competence/damage-inducible protein A Machinery gene
  EL136_RS09830 (NCTC6180_02016) recA 2053519..2054655 (+) 1137 WP_012678688.1 recombinase RecA Machinery gene
  EL136_RS09835 (NCTC6180_02017) spx 2055031..2055429 (+) 399 WP_012516440.1 transcriptional regulator Spx -
  EL136_RS09840 (NCTC6180_02018) - 2055542..2055811 (+) 270 WP_012516439.1 IreB family regulatory phosphoprotein -
  EL136_RS09845 (NCTC6180_02019) ruvX 2055808..2056227 (+) 420 WP_012678687.1 Holliday junction resolvase RuvX -
  EL136_RS09850 (NCTC6180_02020) - 2056237..2056536 (+) 300 WP_012516437.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45971.64 Da        Isoelectric Point: 5.1820

>NTDB_id=1121299 EL136_RS09825 WP_043039523.1 2052154..2053425(+) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQT
LAKYLGKALVFDEQAGQKLDAFFAHRKHTARTPNNQRQAQLIEGSVALQNQTGLAVGGLITVDGVTYVVLPGPPSELKPM
VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKYQTDPTIAPYAKTGEVTLRLSTKADHQALANERLDQLELQ
LLSIRTIDNQPLRRLLYGYGEDNSLARETFELLKRSGKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARM
LGIPLVELQRHGVVSSFTAEQMAAQARCLTDSDIGIGLTGVAGPEELEEQPAGTVFIGLATKNKVESLKVVIGGRSRLDV
RYIATLYAFNMVRKTLLKSENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1121299 EL136_RS09825 WP_043039523.1 2052154..2053425(+) (cinA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGAAAGCTGAACTCATTGCGGTGGGAACCGAGATTCTGACTGGTCAGATTGTGAATACCAATGCTCAATTTCTATCGGA
AAAAATGGCAGAGCTTGGCATTGATGTTTATTTTCAAACAGCTGTAGGAGATAATGAAGAGCGTTTGCTTTCTGTTATTG
ATATTGCTAGCCAGCGAAGTGATTTAGTGATTTTATGTGGTGGTCTTGGTCCAACAGATGATGATCTAACGAAGCAGACC
TTAGCTAAGTATCTGGGAAAAGCTTTGGTCTTTGATGAGCAGGCAGGTCAAAAATTAGATGCTTTTTTTGCACATCGTAA
GCATACTGCTAGGACACCAAACAACCAACGTCAGGCGCAGCTGATTGAAGGCTCTGTTGCTTTGCAAAATCAAACAGGAC
TTGCAGTAGGTGGCTTGATCACTGTAGATGGGGTAACCTATGTTGTCTTACCAGGGCCTCCAAGTGAGTTAAAGCCTATG
GTAAAAAATGAGCTGGTACCCCTTCTTTCAGCTAGTCACGCTAGTCTGTACTCAAGAGTGCTGCGCTTTTTTGGCATTGG
TGAGAGTCAACTGGTGACTGCTCTGGAGGATTTGATTAAGTATCAAACAGATCCTACTATTGCTCCTTATGCAAAGACCG
GCGAGGTAACACTGCGACTATCCACAAAGGCTGATCATCAAGCATTAGCTAATGAAAGGCTGGATCAGCTGGAGTTACAG
CTCTTATCCATAAGAACCATAGATAATCAACCCTTACGGCGTTTGCTTTATGGCTATGGGGAGGATAATTCCTTGGCACG
TGAGACCTTTGAGCTATTGAAGCGAAGTGGCAAGACGATAACAGCAGCTGAAAGCTTGACAGCAGGACTGTTTCAAGCCC
AGCTAACTGATTTTGCGGGAGCTTCACAGGTGTTTAACGGTGGCTTTATCACCTACAGCATTGAAGAAAAAGCAAGAATG
CTTGGTATTCCATTGGTTGAGCTCCAAAGGCATGGTGTTGTGAGCTCTTTTACAGCTGAGCAAATGGCTGCGCAGGCACG
TTGCTTGACCGATTCAGATATCGGTATTGGTCTAACAGGTGTTGCTGGTCCAGAGGAACTCGAGGAGCAGCCAGCAGGAA
CAGTTTTCATTGGCCTTGCCACTAAGAATAAGGTAGAATCTCTTAAAGTTGTCATAGGAGGTCGCAGCCGTTTGGACGTG
CGGTACATTGCTACTCTGTACGCTTTTAATATGGTTCGTAAAACTTTATTAAAATCAGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

70.922

100

0.709
  cinA Streptococcus mitis NCTC 12261

70.743

98.582

0.697
  cinA Streptococcus mitis SK321

70.743

98.582

0.697
  cinA Streptococcus pneumoniae TIGR4

70.264

98.582

0.693
  cinA Streptococcus pneumoniae Rx1

70.264

98.582

0.693
  cinA Streptococcus pneumoniae R6

70.264

98.582

0.693
  cinA Streptococcus pneumoniae D39

70.024

98.582

0.69
  cinA Streptococcus suis isolate S10

54.177

99.054

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

47.129

98.818

0.466

Multiple sequence alignment