Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL139_RS03860 Genome accession   NZ_LR134316
Coordinates   721286..722557 (+) Length   423 a.a.
NCBI ID   WP_111717758.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 716286..727557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS03835 (NCTC6181_00781) mutL 716416..718398 (+) 1983 WP_111717762.1 DNA mismatch repair endonuclease MutL -
  EL139_RS03840 (NCTC6181_00782) - 718409..719629 (+) 1221 WP_111717761.1 MFS transporter -
  EL139_RS03845 (NCTC6181_00783) ruvA 719631..720224 (+) 594 WP_111717760.1 Holliday junction branch migration protein RuvA -
  EL139_RS03850 (NCTC6181_00784) - 720234..720806 (+) 573 WP_111717759.1 DNA-3-methyladenine glycosylase I -
  EL139_RS03855 (NCTC6181_00785) - 720809..721096 (+) 288 Protein_715 VOC family protein -
  EL139_RS03860 (NCTC6181_00786) cinA 721286..722557 (+) 1272 WP_111717758.1 competence/damage-inducible protein A Machinery gene
  EL139_RS03865 (NCTC6181_00787) recA 722662..723798 (+) 1137 WP_111717757.1 recombinase RecA Machinery gene
  EL139_RS03870 (NCTC6181_00788) spx 724091..724489 (+) 399 WP_003053105.1 transcriptional regulator Spx -
  EL139_RS03875 (NCTC6181_00789) - 724601..724870 (+) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  EL139_RS03880 (NCTC6181_00790) ruvX 724867..725286 (+) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  EL139_RS03885 (NCTC6181_00791) - 725297..725602 (+) 306 WP_003045716.1 DUF1292 domain-containing protein -
  EL139_RS03890 (NCTC6181_00793) - 725919..727481 (+) 1563 WP_111717756.1 DUF2079 domain-containing protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45982.31 Da        Isoelectric Point: 4.6585

>NTDB_id=1121216 EL139_RS03860 WP_111717758.1 721286..722557(+) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLDFEEQASQKLDDFYASHKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSLEEKAKM
LGIPLEDLISHGVVSAYTAEKMAEQTRLLTGADIGVSLTGVAGPDMLEDQPAGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1121216 EL139_RS03860 WP_111717758.1 721286..722557(+) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAAGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGCGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGACTTTGAAGAACAAGCTAGTCAAAAATTAGACGATTTTTATGCCAGTCATAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCCATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACTATTGCACCTTATGCTAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGCTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCCTGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAACAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGACCAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGGGACGGAGCCGCTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.868

100

0.719
  cinA Streptococcus mitis SK321

70.504

98.582

0.695
  cinA Streptococcus mitis NCTC 12261

69.544

98.582

0.686
  cinA Streptococcus pneumoniae TIGR4

68.825

98.582

0.678
  cinA Streptococcus pneumoniae Rx1

68.825

98.582

0.678
  cinA Streptococcus pneumoniae R6

68.825

98.582

0.678
  cinA Streptococcus pneumoniae D39

68.585

98.582

0.676
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

45.714

99.291

0.454

Multiple sequence alignment