Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL115_RS09040 Genome accession   NZ_LR134307
Coordinates   1793580..1794848 (-) Length   422 a.a.
NCBI ID   WP_048801170.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1788580..1799848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS09005 (NCTC10708_01785) - 1789447..1789758 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  EL115_RS09010 (NCTC10708_01786) ruvX 1789776..1790195 (-) 420 WP_003071469.1 Holliday junction resolvase RuvX -
  EL115_RS09015 (NCTC10708_01787) - 1790195..1790461 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  EL115_RS09020 (NCTC10708_01788) - 1790585..1791142 (-) 558 WP_003071476.1 SP0191 family lipoprotein -
  EL115_RS09025 (NCTC10708_01789) - 1791247..1791816 (-) 570 WP_126441811.1 SP0191 family lipoprotein -
  EL115_RS09030 (NCTC10708_01790) spx 1791901..1792299 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  EL115_RS09035 (NCTC10708_01791) recA 1792386..1793531 (-) 1146 WP_006269775.1 recombinase RecA Machinery gene
  EL115_RS09040 (NCTC10708_01792) cinA 1793580..1794848 (-) 1269 WP_048801170.1 competence/damage-inducible protein A Machinery gene
  EL115_RS09045 (NCTC10708_01793) - 1795004..1795633 (-) 630 WP_006269784.1 ABC transporter ATP-binding protein -
  EL115_RS09050 (NCTC10708_01794) - 1795630..1797639 (-) 2010 WP_006269786.1 hypothetical protein -
  EL115_RS09055 - 1797737..1798006 (-) 270 WP_020998096.1 hypothetical protein -
  EL115_RS09060 (NCTC10708_01795) - 1798389..1799243 (+) 855 WP_126441812.1 Rgg/GadR/MutR family transcriptional regulator -
  EL115_RS09065 (NCTC10708_01796) - 1799404..1799817 (+) 414 WP_006269778.1 EamA family transporter -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 46097.84 Da        Isoelectric Point: 5.6090

>NTDB_id=1120921 EL115_RS09040 WP_048801170.1 1793580..1794848(-) (cinA) [Streptococcus milleri strain NCTC10708]
MKAEIIAVGTEILTGQIINTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSILEIAKKRSDLVILCGGLGPTEDDLTKQV
LAKFLNRRLVFDQVAMEKLDRFFASRLDYVRTPNNERQAQIVEDSTSLQNETGLAVGGVIEVSGVTYVVLPGPPSELKPM
VNNELIPILATDQKLYSRVLRFFGIGESQLVTLLGDLIDAQIDPTIAPYAKTGEVTLRLSTKASSQKEADTKFAYLEKKI
LAVQTFEKQRLVDLFYAYGDDNSLAQTTFELLRRAGKTVTAAESLTAGLFQATLANFSGASNVFSGGFVTYSMEEKSRML
DIPLADLEKHGVVSAFTAKKMAEQARKLTASDYAVSLTGVAGPDSLEGYPAGTVYIGLATTENVQSFKVNIAGRSRTDVR
KIAVLHAFNQLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1120921 EL115_RS09040 WP_048801170.1 1793580..1794848(-) (cinA) [Streptococcus milleri strain NCTC10708]
ATGAAAGCAGAAATTATTGCTGTAGGTACTGAAATTCTGACCGGGCAAATTATCAATACGAATGCTCAATTTTTATCGGA
AAAGTTAGCGAGTCTAGGGATTGATGTTTATTTCCAGACTGCTGTCGGTGACAATGAAAATCGTCTTTTATCTATTTTGG
AAATTGCAAAGAAACGGAGCGATCTTGTCATTCTTTGTGGTGGCTTGGGTCCAACAGAAGATGACTTGACCAAACAGGTG
TTGGCAAAATTTTTAAATCGCAGGTTGGTCTTTGACCAAGTAGCTATGGAAAAATTAGATCGTTTCTTCGCGAGTCGACT
GGACTATGTTCGAACACCAAATAATGAGCGGCAAGCTCAAATAGTGGAAGATTCGACTTCTCTACAAAACGAAACCGGAC
TTGCGGTGGGGGGCGTGATTGAAGTAAGTGGTGTAACTTATGTTGTTCTGCCTGGTCCACCTAGTGAATTAAAACCTATG
GTGAACAATGAGCTGATTCCGATTTTAGCAACGGATCAAAAATTGTATTCAAGAGTTTTGCGCTTCTTTGGCATTGGTGA
AAGTCAATTAGTAACTCTTTTAGGAGATTTAATTGATGCTCAGATCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACAAAGGCTAGCAGTCAAAAAGAAGCAGATACTAAGTTTGCTTATTTGGAAAAGAAAATT
TTAGCTGTACAGACTTTTGAGAAACAACGTTTAGTGGATCTTTTCTATGCTTATGGAGATGATAATTCTCTAGCGCAGAC
AACTTTTGAATTGTTGAGGAGAGCAGGCAAGACTGTTACAGCAGCCGAAAGTTTGACTGCAGGCCTTTTTCAAGCAACTT
TGGCAAACTTTTCTGGAGCCTCTAATGTCTTTAGTGGTGGCTTTGTCACTTACAGTATGGAGGAAAAGAGCCGCATGCTG
GACATTCCTTTGGCAGACTTGGAAAAACATGGAGTTGTTTCTGCTTTTACAGCAAAGAAAATGGCTGAGCAGGCCAGAAA
ATTGACTGCCAGTGACTATGCAGTGAGTTTGACGGGTGTGGCAGGTCCAGACAGCTTAGAAGGATATCCGGCAGGGACAG
TTTATATTGGCTTAGCAACCACAGAGAATGTACAATCTTTTAAGGTTAATATTGCCGGTCGTAGTCGGACTGATGTACGA
AAAATAGCTGTTCTGCATGCTTTCAATCAGTTACGAAAAACTTTATTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.402

99.052

0.737
  cinA Streptococcus pneumoniae TIGR4

73.923

99.052

0.732
  cinA Streptococcus pneumoniae Rx1

73.923

99.052

0.732
  cinA Streptococcus pneumoniae R6

73.923

99.052

0.732
  cinA Streptococcus pneumoniae D39

73.684

99.052

0.73
  cinA Streptococcus mitis NCTC 12261

73.445

99.052

0.727
  cinA Streptococcus mutans UA159

71.158

100

0.713
  cinA Streptococcus suis isolate S10

55.529

98.578

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

99.052

0.445

Multiple sequence alignment