Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL115_RS08395 Genome accession   NZ_LR134307
Coordinates   1673284..1674306 (-) Length   340 a.a.
NCBI ID   WP_126441773.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1668284..1679306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS08360 (NCTC10708_01657) - 1669305..1670504 (-) 1200 WP_126441770.1 acetate kinase -
  EL115_RS08365 (NCTC10708_01658) comYH 1670551..1671504 (-) 954 WP_115263521.1 class I SAM-dependent methyltransferase Machinery gene
  EL115_RS08370 (NCTC10708_01659) comGG 1671589..1671915 (-) 327 WP_003070783.1 competence type IV pilus minor pilin ComGG -
  EL115_RS08375 (NCTC10708_01660) comGF/cglF 1671896..1672333 (-) 438 WP_126441771.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL115_RS08380 (NCTC10708_01661) comGE/cglE 1672317..1672610 (-) 294 WP_126441772.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL115_RS08385 (NCTC10708_01662) comYD 1672582..1672980 (-) 399 WP_006269995.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL115_RS08390 (NCTC10708_01663) comYC 1672970..1673287 (-) 318 WP_006269985.1 competence type IV pilus major pilin ComGC Machinery gene
  EL115_RS08395 (NCTC10708_01664) comYB 1673284..1674306 (-) 1023 WP_126441773.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL115_RS08400 (NCTC10708_01665) comYA 1674248..1675189 (-) 942 WP_126441774.1 competence type IV pilus ATPase ComGA Machinery gene
  EL115_RS08405 (NCTC10708_01666) - 1675259..1675624 (-) 366 WP_126441775.1 DUF1033 family protein -
  EL115_RS08410 (NCTC10708_01667) glnA 1675812..1677158 (-) 1347 WP_006269977.1 type I glutamate--ammonia ligase -
  EL115_RS08415 (NCTC10708_01668) - 1677197..1677556 (-) 360 WP_126441776.1 MerR family transcriptional regulator -
  EL115_RS08420 (NCTC10708_01669) - 1677633..1678163 (-) 531 WP_006269975.1 FUSC family protein -
  EL115_RS08425 - 1678303..1678587 (-) 285 WP_006269982.1 2'-5' RNA ligase family protein -
  EL115_RS08430 (NCTC10708_01670) - 1678590..1678796 (-) 207 WP_006268044.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38937.16 Da        Isoelectric Point: 9.6570

>NTDB_id=1120916 EL115_RS08395 WP_126441773.1 1673284..1674306(-) (comYB) [Streptococcus milleri strain NCTC10708]
MQQDISLLSRQKRKKLSIVRQKKVVELLNNLFSSGFHLAEMIDFLKRSALLEKTYVEKMKEGLATGKPFSEIMASLGFSD
SVVTQLSLAELHGNLSLSLTKIEEYLENVSKVKKKLIEVATYPFILLIFLVFIMLGLRNYLLPQLERQNSATQLISQLPQ
IFLGSLGVVLVLLAIGFYWFRKSSKIVVFSFLARLPFCGTFIQAYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSQVVKHYPFFKKELGLIIEYGEVKSKLGCELEVYAQKTWEKFFSRINQAMNLVQPLVFVFVALV
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=1120916 EL115_RS08395 WP_126441773.1 1673284..1674306(-) (comYB) [Streptococcus milleri strain NCTC10708]
ATGCAGCAGGACATATCACTTTTGAGCAGGCAGAAACGGAAAAAATTATCCATAGTTAGGCAGAAAAAAGTCGTAGAGTT
GCTGAATAATCTTTTTTCTAGTGGCTTTCATTTAGCAGAAATGATTGATTTTTTGAAGCGGAGTGCCCTGCTAGAAAAAA
CCTATGTAGAAAAGATGAAAGAGGGTTTAGCAACAGGAAAACCTTTTTCAGAAATTATGGCTAGTTTAGGATTTTCAGAT
AGTGTTGTCACCCAGCTTTCACTGGCAGAGCTACATGGGAATCTCTCACTCAGCCTGACTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAGTCAAGAAAAAGTTAATTGAGGTAGCCACTTATCCATTCATTTTACTTATTTTTTTAGTATTCATTA
TGTTAGGGCTGCGCAATTATTTACTTCCGCAGTTAGAACGCCAAAATAGTGCAACGCAGCTGATTAGTCAGTTGCCGCAA
ATTTTTCTGGGTTCATTAGGAGTAGTCCTTGTTTTGTTAGCGATAGGTTTTTATTGGTTTAGAAAAAGCTCAAAAATAGT
AGTGTTTAGCTTCTTGGCTCGACTTCCTTTTTGTGGAACTTTTATTCAAGCGTATTTGACAGCTTATTATGCGCGCGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTCAGTCAGATTTTTCAGATGATGCAAGGGCAACGCTCTGCTATGTTTCAA
GAAATTGGAAAAGACTTAGAAGTTGCACTGCAAAATGGTCAGGAATTTTCCCAAGTGGTTAAACACTACCCGTTTTTTAA
AAAGGAATTGGGTTTGATAATTGAATACGGTGAAGTGAAATCCAAATTGGGGTGTGAATTAGAAGTTTATGCTCAAAAAA
CGTGGGAGAAGTTTTTTAGTCGGATCAATCAAGCTATGAACTTAGTGCAGCCGCTTGTCTTTGTTTTTGTGGCACTGGTT
ATTGTTTTATTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.529

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

70.118

99.412

0.697
  comGB/cglB Streptococcus mitis SK321

68.75

98.824

0.679
  comGB/cglB Streptococcus pneumoniae TIGR4

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae R6

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae Rx1

68.452

98.824

0.676
  comGB/cglB Streptococcus pneumoniae D39

68.452

98.824

0.676
  comYB Streptococcus mutans UA159

62.281

100

0.626
  comYB Streptococcus mutans UA140

61.988

100

0.624
  comGB Lactococcus lactis subsp. cremoris KW2

52.522

99.118

0.521

Multiple sequence alignment