Detailed information NTG1120911

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: EL115_RS08365
• Genome accession: NZ_LR134307
• Coordinates: 1670551..1671504 (-)
• Length: 317 a.a.
• NCBI ID: WP_115263521.1
• Uniprot ID: A0A380L472
• Organism: Streptococcus milleri strain NCTC10708
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1665551..1676504

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS08355 (NCTC10708_01656)	glmS	1667100..1668914 (-)	1815	WP_126441769.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
EL115_RS08360 (NCTC10708_01657)	-	1669305..1670504 (-)	1200	WP_126441770.1	acetate kinase	-
EL115_RS08365 (NCTC10708_01658)	comYH	1670551..1671504 (-)	954	WP_115263521.1	class I SAM-dependent methyltransferase	Machinery gene
EL115_RS08370 (NCTC10708_01659)	comGG	1671589..1671915 (-)	327	WP_003070783.1	competence type IV pilus minor pilin ComGG	-
EL115_RS08375 (NCTC10708_01660)	comGF/cglF	1671896..1672333 (-)	438	WP_126441771.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL115_RS08380 (NCTC10708_01661)	comGE/cglE	1672317..1672610 (-)	294	WP_126441772.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL115_RS08385 (NCTC10708_01662)	comYD	1672582..1672980 (-)	399	WP_006269995.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL115_RS08390 (NCTC10708_01663)	comYC	1672970..1673287 (-)	318	WP_006269985.1	competence type IV pilus major pilin ComGC	Machinery gene
EL115_RS08395 (NCTC10708_01664)	comYB	1673284..1674306 (-)	1023	WP_126441773.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL115_RS08400 (NCTC10708_01665)	comYA	1674248..1675189 (-)	942	WP_126441774.1	competence type IV pilus ATPase ComGA	Machinery gene
EL115_RS08405 (NCTC10708_01666)	-	1675259..1675624 (-)	366	WP_126441775.1	DUF1033 family protein	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 35846.59 Da
• Isoelectric Point: 4.3125

>NTDB_id=1120911 EL115_RS08365 WP_115263521.1 1670551..1671504(-) (comYH) [Streptococcus milleri strain NCTC10708]
MNFEKIEQAYSLLLENVQELQNTLLTNFYDALVEQNGVYLDGNTELAIVKKNNETLKSLKLGKEEWRRAYQFLLMKAAQT
EPLQANHQFTPDSIGFIVTFLIDQLSNKEHIDVLEIGSGMGNLAETILNNTNKNVDYLGLELDDLLIDISASIADVMDAK
VSFVQGDAVRPQVLKESDVIISDLPVGFYPDDNIATRYEVASRQEHTYAHHLLMEQSLKYLKSDGYAIFLAPNDLLTSTQ
SDLLKNWLQKHAQIVAMIALPESLFGNAAYAKTIFVLKKQDEQAVQPFVYALSDLQNQADLLTFSEKFQNWSQESEI

Nucleotide

• Length: 954 bp

>NTDB_id=1120911 EL115_RS08365 WP_115263521.1 1670551..1671504(-) (comYH) [Streptococcus milleri strain NCTC10708]
ATGAATTTTGAAAAAATAGAACAGGCTTATTCGCTTTTGTTAGAAAATGTCCAGGAGCTCCAAAATACTCTTTTGACGAA
TTTTTATGATGCTTTGGTCGAGCAAAATGGGGTTTATCTGGATGGAAATACAGAGCTAGCTATTGTCAAAAAAAATAATG
AAACACTTAAATCTTTGAAATTAGGTAAAGAAGAATGGCGACGAGCATACCAATTTTTGCTGATGAAAGCGGCTCAAACA
GAGCCTTTGCAAGCTAATCATCAATTTACTCCGGATTCTATTGGTTTTATCGTAACATTTCTCATTGACCAATTGAGTAA
TAAAGAACATATTGATGTGTTGGAAATTGGTAGTGGAATGGGAAATTTGGCAGAAACCATTCTTAATAATACAAATAAAA
ACGTGGATTATCTAGGGCTGGAATTGGACGATCTGCTAATTGATATATCAGCCAGTATCGCAGATGTGATGGATGCAAAA
GTTAGTTTTGTGCAAGGTGATGCGGTGCGCCCGCAAGTATTGAAAGAAAGCGATGTGATTATCAGTGATTTACCAGTTGG
CTTTTATCCTGATGATAACATTGCGACGCGCTATGAAGTGGCTAGTAGACAGGAGCATACTTATGCTCATCATTTGTTAA
TGGAACAATCGCTCAAGTATCTCAAATCGGATGGTTATGCTATTTTCCTTGCACCAAATGATTTACTGACTAGCACACAA
AGTGATTTATTAAAAAATTGGTTGCAGAAGCATGCACAAATAGTTGCAATGATTGCGTTACCAGAGTCTCTTTTTGGAAA
TGCAGCATACGCTAAAACAATTTTTGTACTGAAAAAGCAAGATGAACAAGCTGTCCAACCATTTGTTTATGCTTTATCTG
ATTTGCAGAATCAAGCGGATTTATTGACATTTAGCGAAAAGTTTCAAAATTGGAGCCAAGAAAGTGAAATTTAA

Domains

Predicted by InterproScan.

• N-6 DNA Methylase (N6_Mtase) (68-294)

3D structure

• AlphaFold DB: A0A380L472

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA140	60.952	99.369	0.606
comYH	Streptococcus mutans UA159	60.635	99.369	0.603