Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EL115_RS04045 Genome accession   NZ_LR134307
Coordinates   812205..812909 (+) Length   234 a.a.
NCBI ID   WP_126441357.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 807205..817909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS04020 (NCTC10708_00811) - 807564..808769 (+) 1206 WP_172594014.1 multidrug efflux MFS transporter -
  EL115_RS04025 rpmG 808753..808902 (+) 150 WP_080979224.1 50S ribosomal protein L33 -
  EL115_RS04030 (NCTC10708_00812) secG 808942..809175 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  EL115_RS04035 (NCTC10708_00813) rnr 809268..811404 (+) 2137 Protein_773 ribonuclease R -
  EL115_RS04040 (NCTC10708_00814) smpB 811570..812037 (+) 468 WP_003034458.1 SsrA-binding protein SmpB -
  EL115_RS04045 (NCTC10708_00815) comEA/celA/cilE 812205..812909 (+) 705 WP_126441357.1 helix-hairpin-helix domain-containing protein Machinery gene
  EL115_RS04050 (NCTC10708_00816) comEC/celB 812893..815121 (+) 2229 WP_126441358.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL115_RS04055 (NCTC10708_00817) - 815201..815920 (+) 720 WP_126441359.1 DUF805 domain-containing protein -
  EL115_RS04060 (NCTC10708_00819) - 816365..817351 (+) 987 WP_126441360.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25424.76 Da        Isoelectric Point: 8.2610

>NTDB_id=1120885 EL115_RS04045 WP_126441357.1 812205..812909(+) (comEA/celA/cilE) [Streptococcus milleri strain NCTC10708]
MLEVIITKIKEYKILVSLSLIGLIIAGFFMMTSKSARQSNVGDIAQETTNAKLERKETSTETKKKQQKEETESQKNLASE
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVATMGENVTNAASNNGQTLTT
DTDGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYREANGKFNSVDDLKNISGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1120885 EL115_RS04045 WP_126441357.1 812205..812909(+) (comEA/celA/cilE) [Streptococcus milleri strain NCTC10708]
ATGTTAGAGGTAATCATCACAAAAATAAAAGAGTATAAAATTTTAGTTAGTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTATGATGACTAGTAAATCTGCTAGACAATCTAATGTGGGAGATATTGCACAAGAGACCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT
AAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAACTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA
GATACCGATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCCAATTTGTCTGATTTACAGTCTATTTC
TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGGCAAATGGAAAATTTAATTCTGTTGATGATCTAA
AAAATATATCAGGAGTTGGTGCTAAAACATTAGAGAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(169-232)

SLBB domain (SLBB)

(87-140)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

50.633

100

0.513
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus pneumoniae D39

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

50.215

99.573

0.5
  comEA Streptococcus thermophilus LMD-9

42.553

100

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

38.627

99.573

0.385

Multiple sequence alignment