Detailed information NTG1120886

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL115_RS04050
• Genome accession: NZ_LR134307
• Coordinates: 812893..815121 (+)
• Length: 742 a.a.
• NCBI ID: WP_126441358.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC10708
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 807893..820121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL115_RS04025	rpmG	808753..808902 (+)	150	WP_080979224.1	50S ribosomal protein L33	-
EL115_RS04030 (NCTC10708_00812)	secG	808942..809175 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
EL115_RS04035 (NCTC10708_00813)	rnr	809268..811404 (+)	2137	Protein_773	ribonuclease R	-
EL115_RS04040 (NCTC10708_00814)	smpB	811570..812037 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
EL115_RS04045 (NCTC10708_00815)	comEA/celA/cilE	812205..812909 (+)	705	WP_126441357.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL115_RS04050 (NCTC10708_00816)	comEC/celB	812893..815121 (+)	2229	WP_126441358.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL115_RS04055 (NCTC10708_00817)	-	815201..815920 (+)	720	WP_126441359.1	DUF805 domain-containing protein	-
EL115_RS04060 (NCTC10708_00819)	-	816365..817351 (+)	987	WP_126441360.1	Gfo/Idh/MocA family protein	-
EL115_RS04065 (NCTC10708_00820)	-	817376..818029 (+)	654	WP_006269516.1	uracil-DNA glycosylase	-
EL115_RS04070 (NCTC10708_00821)	-	818038..818508 (+)	471	WP_126441361.1	NUDIX hydrolase	-
EL115_RS04075 (NCTC10708_00822)	-	818520..819794 (+)	1275	WP_126441362.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85443.50 Da
• Isoelectric Point: 10.0290

>NTDB_id=1120886 EL115_RS04050 WP_126441358.1 812893..815121(+) (comEC/celB) [Streptococcus milleri strain NCTC10708]
MSQWIKIFPIKPIYIAFLLVWLYFAIYQSSWLAWFCFIFLIIRLFVLYSPKKCFITLMFLACFAAFFFVRREMAEWQTKA
EPSSVRQVAVLPDTIKVNGDSLSFRGKANRQTYQIYYKLKSKEEQSAFQNLSSLVTLTVEGEFDIPEKQRNFSGFDYQAY
LKTQGIYRILKVDQILSSQDRVSFQPFEWLSSWRRKALVFIKRNFPNPMNHYMTGLLFGALETDFDEMSDLYSSLGIIHL
FALSGMQVGFFMEGFRKLLLKLGLTKEMVHKCQYPFSFFYAGMTGFSVSVVRSLIQKLLSQHGITKLDNFALTIMVLSLL
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKVVVESSIISLGVLPILIFYFGEFQPWSILLTFVFSLIFDIVMLPGLT
LIFLISPFIKLIQVNFLFEGLENSIRWIANVFGRPIVFGQPSSLLLVVMLLVLAILYDVRKNKKWVILLSLCLAILFFIT
KFPLQNEITMVDVGQGDSLFLRDWKGRNVLIDVGGREEIRTKESWQKRTTKSNAEKTLIPYLKSRGIDTIDTLILTNPNA
DYAGDVLKVVKKFAVKKIFISRSSLNDADFLNKLKETKTFVHVVKQGDKLPIFDHHLQVLSGTNKNDQSLVLYGQFFRTR
FLFMSNLTEEDEVKLMQLYPKLKTDVLKVGQHGAKNSSHSKFLQQIEPAVALISVGKNNQSKSPNQEMIERLNRLNAKIY
RTDERGAIKFSGWTKWQLETVQ

Nucleotide

• Length: 2229 bp

>NTDB_id=1120886 EL115_RS04050 WP_126441358.1 812893..815121(+) (comEC/celB) [Streptococcus milleri strain NCTC10708]
ATGTCACAGTGGATTAAGATATTTCCGATTAAACCAATTTACATTGCTTTCTTACTTGTCTGGCTATATTTTGCAATCTA
TCAAAGTAGCTGGTTGGCTTGGTTTTGTTTTATTTTTCTAATAATCCGTCTTTTTGTCCTTTATTCACCGAAAAAATGTT
TCATAACTTTAATGTTTCTCGCTTGTTTTGCTGCTTTTTTCTTTGTTCGTAGAGAAATGGCAGAGTGGCAAACAAAAGCA
GAACCTTCTTCTGTAAGACAAGTAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCGCTTTCTTTTCGCGGTAA
AGCAAATAGGCAGACTTATCAAATTTACTACAAATTGAAATCAAAAGAAGAACAGTCGGCTTTTCAAAATCTATCCAGTC
TTGTTACATTGACTGTTGAAGGAGAATTTGATATTCCTGAAAAGCAGCGCAATTTTTCTGGTTTTGATTATCAAGCCTAT
CTAAAAACACAAGGGATTTATCGAATTTTAAAGGTGGATCAAATTTTGTCTAGTCAAGATAGGGTTAGCTTCCAACCGTT
TGAGTGGCTGTCTAGCTGGCGAAGAAAGGCATTGGTTTTCATTAAGAGAAATTTTCCAAATCCGATGAATCATTACATGA
CAGGGCTCTTATTTGGCGCATTAGAGACAGATTTTGATGAAATGAGTGATCTTTATTCTAGCTTGGGAATTATTCATTTA
TTTGCGTTATCTGGCATGCAAGTTGGCTTTTTTATGGAAGGATTTCGTAAGTTGCTTTTGAAGCTGGGACTTACGAAGGA
AATGGTTCATAAATGCCAATATCCGTTTTCTTTCTTTTATGCAGGAATGACTGGATTTTCAGTATCCGTTGTACGGAGCT
TAATTCAGAAATTATTGTCGCAACATGGTATCACTAAATTAGATAATTTTGCTTTAACAATAATGGTGTTGTCCTTGCTT
ATGCCATCTTTTCTTTTAACGGCAGGAGGAGTTCTCTCCTGTGCCTATGCTTTTGTTATTAGTGTTATAGATTTTGAAAG
TCTGACTTCTTGGAGAAAAGTTGTGGTAGAGAGTAGTATCATTTCACTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GAGAATTTCAACCTTGGTCTATTTTATTGACATTTGTTTTTTCACTAATTTTTGATATAGTGATGCTACCGGGTTTAACA
CTGATTTTTCTCATTTCACCTTTCATAAAGCTCATTCAAGTAAATTTTCTTTTTGAAGGCTTAGAAAATAGTATTCGTTG
GATAGCAAATGTCTTTGGCAGACCAATCGTTTTTGGGCAACCTAGCTCGCTTTTATTAGTTGTTATGCTGCTTGTACTGG
CTATTTTGTATGATGTTAGAAAAAATAAAAAATGGGTGATATTGCTCAGCTTGTGTCTTGCTATACTATTTTTTATAACT
AAATTTCCTTTGCAAAATGAGATCACAATGGTTGATGTTGGACAGGGAGACAGTCTTTTTTTGAGAGACTGGAAAGGTAG
AAATGTATTAATTGACGTTGGAGGACGTGAAGAAATTAGAACAAAAGAATCTTGGCAAAAACGAACAACTAAATCAAATG
CGGAGAAAACTTTGATTCCTTACCTAAAAAGTCGTGGTATAGATACGATTGATACTCTAATCTTAACAAATCCTAATGCA
GATTATGCGGGAGATGTATTAAAAGTGGTTAAAAAGTTTGCGGTAAAGAAAATTTTTATTTCCAGAAGTAGTTTGAATGA
TGCAGACTTTTTAAATAAATTAAAGGAGACAAAGACGTTTGTTCATGTCGTAAAACAAGGAGACAAACTTCCTATTTTTG
ATCATCATTTGCAAGTTCTTTCTGGTACGAATAAGAATGATCAATCGCTAGTTTTATATGGTCAATTTTTTCGTACAAGG
TTTTTATTTATGAGCAATTTAACAGAAGAGGATGAAGTAAAGCTAATGCAACTTTATCCAAAGCTAAAAACAGATGTCTT
GAAGGTTGGGCAACATGGAGCCAAAAATTCATCACATTCAAAATTTTTACAGCAAATAGAACCGGCAGTTGCACTCATTT
CTGTTGGGAAAAATAACCAATCCAAATCTCCGAATCAAGAAATGATAGAGCGATTGAATCGCTTAAATGCGAAGATTTAT
CGAACAGATGAACGAGGGGCGATCAAGTTTTCAGGATGGACAAAATGGCAATTAGAAACTGTTCAATAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-577)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	54.826	100	0.551
comEC/celB	Streptococcus mitis SK321	54.752	100	0.551
comEC/celB	Streptococcus pneumoniae TIGR4	53.949	100	0.543
comEC/celB	Streptococcus pneumoniae Rx1	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae D39	53.146	100	0.535
comEC/celB	Streptococcus pneumoniae R6	53.146	100	0.535
comEC	Lactococcus lactis subsp. cremoris KW2	46.703	100	0.468