Detailed information NTG1120532

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EL096_RS02175
• Genome accession: NZ_LR134294
• Coordinates: 409678..410328 (+)
• Length: 216 a.a.
• NCBI ID: WP_114880828.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NCTC12977
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 404678..415328

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL096_RS02130 (NCTC12977_00413)	-	405162..405377 (+)	216	WP_001232082.1	YozE family protein	-
EL096_RS02135 (NCTC12977_00414)	-	405463..406431 (+)	969	WP_000658183.1	PhoH family protein	-
EL096_RS02145 (NCTC12977_00415)	-	406624..407124 (+)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
EL096_RS02150	-	407127..407452 (+)	326	Protein_410	TfoX/Sxy family protein	-
EL096_RS11750	ald	407753..408864 (-)	1112	Protein_411	alanine dehydrogenase	-
EL096_RS02170 (NCTC12977_00419)	-	409041..409610 (+)	570	WP_114880827.1	GNAT family N-acetyltransferase	-
EL096_RS02175 (NCTC12977_00420)	comEA/celA/cilE	409678..410328 (+)	651	WP_114880828.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL096_RS02180 (NCTC12977_00421)	comEC/celB	410312..412552 (+)	2241	WP_044727637.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL096_RS02185	-	412731..412919 (+)	189	WP_001809102.1	hypothetical protein	-
EL096_RS02190 (NCTC12977_00422)	-	412951..413538 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
EL096_RS02195 (NCTC12977_00424)	-	413542..414722 (+)	1181	Protein_417	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23274.65 Da
• Isoelectric Point: 6.0746

>NTDB_id=1120532 EL096_RS02175 WP_114880828.1 409678..410328(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain NCTC12977]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNVQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKRLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=1120532 EL096_RS02175 WP_114880828.1 409678..410328(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain NCTC12977]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATGTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGAGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	94.907	100	0.949
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Streptococcus thermophilus LMD-9	39.738	100	0.421
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361