Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL097_RS08590 Genome accession   NZ_LR134293
Coordinates   1694910..1695584 (-) Length   224 a.a.
NCBI ID   WP_003048303.1    Uniprot ID   A0A2D4DMP2
Organism   Streptococcus canis strain NCTC12191     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1689910..1700584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS08570 (NCTC12191_01712) - 1691072..1691671 (-) 600 WP_003048308.1 class I SAM-dependent methyltransferase -
  EL097_RS08575 (NCTC12191_01713) coaA 1691939..1692859 (+) 921 WP_003048306.1 type I pantothenate kinase -
  EL097_RS08580 (NCTC12191_01714) rpsT 1692913..1693161 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  EL097_RS08585 (NCTC12191_01715) ciaH 1693607..1694917 (-) 1311 WP_003048304.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EL097_RS08590 (NCTC12191_01716) ciaR 1694910..1695584 (-) 675 WP_003048303.1 response regulator transcription factor Regulator
  EL097_RS08595 (NCTC12191_01717) - 1695787..1698324 (-) 2538 WP_003048301.1 M1 family metallopeptidase -
  EL097_RS08605 (NCTC12191_01718) phoU 1698530..1699183 (-) 654 WP_003048299.1 phosphate signaling complex protein PhoU -
  EL097_RS08610 (NCTC12191_01719) pstB 1699262..1700020 (-) 759 WP_003048297.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25693.73 Da        Isoelectric Point: 4.4740

>NTDB_id=1120518 EL097_RS08590 WP_003048303.1 1694910..1695584(-) (ciaR) [Streptococcus canis strain NCTC12191]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLSFGNVVVDLRRKEVQVDGEPIELLGKEFDLLVY
ILQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTGFVDKLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1120518 EL097_RS08590 WP_003048303.1 1694910..1695584(-) (ciaR) [Streptococcus canis strain NCTC12191]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGTTTATCGAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
GATGCAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGATCTCATGT
TACCAGAAAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGGGAAAAAGATATTAAAATTCCAGTTTTGATTATGACAGCC
AAAGAAAGCATAGATGATAAGGGACATGGGTTTGAACTAGGAGCAGATGATTATCTAACCAAGCCGTTTTACCTTGAAGA
ATTAAAGATGCGCATCCAGGCCCTGTTAAAACGTACGGGCAAATTCACTGATAAAAATCTAAGTTTTGGTAATGTGGTGG
TGGATTTAAGACGAAAAGAAGTTCAAGTCGATGGGGAACCCATTGAGCTATTAGGAAAAGAGTTCGACTTATTGGTTTAC
ATATTGCAAAACCAAAATGTGATCTTACCCAAGACCCAAATTTTTGATCGCTTATGGGGGTTTGACAGCGACACGACAAT
CTCAGTTGTAGAGGTTTATGTCTCTAAAATTAGAAAAAAATTAAAAGGTACTGGTTTTGTTGATAAACTCCAAACCCTGA
GAAGTGTAGGTTATATTCTAAAAAACAATGAGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2D4DMP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae D39

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae R6

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae TIGR4

84.685

99.107

0.839
  ciaR Streptococcus mutans UA159

83.333

99.107

0.826
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.222

100

0.384
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371
  micA Streptococcus pneumoniae Cp1015

34.615

100

0.362
  vicR Streptococcus mutans UA159

34.615

100

0.362

Multiple sequence alignment