Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL097_RS03560 Genome accession   NZ_LR134293
Coordinates   669564..670835 (+) Length   423 a.a.
NCBI ID   WP_003045727.1    Uniprot ID   A0AAV3FVD6
Organism   Streptococcus canis strain NCTC12191     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 664564..675835
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS03535 (NCTC12191_00699) mutL 664698..666680 (+) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL -
  EL097_RS03540 (NCTC12191_00700) - 666691..667929 (+) 1239 WP_003045734.1 MFS transporter -
  EL097_RS03545 (NCTC12191_00701) ruvA 667913..668509 (+) 597 WP_003045733.1 Holliday junction branch migration protein RuvA -
  EL097_RS03550 (NCTC12191_00702) - 668519..669091 (+) 573 WP_003045731.1 DNA-3-methyladenine glycosylase I -
  EL097_RS11030 - 669289..669447 (+) 159 WP_223824822.1 VOC family protein -
  EL097_RS03560 (NCTC12191_00704) cinA 669564..670835 (+) 1272 WP_003045727.1 competence/damage-inducible protein A Machinery gene
  EL097_RS03565 (NCTC12191_00705) recA 670940..672076 (+) 1137 WP_003045726.1 recombinase RecA Machinery gene
  EL097_RS03570 (NCTC12191_00706) spx 672474..672872 (+) 399 WP_003045722.1 transcriptional regulator Spx -
  EL097_RS03575 (NCTC12191_00707) - 672984..673253 (+) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  EL097_RS03580 (NCTC12191_00708) ruvX 673250..673669 (+) 420 WP_039994721.1 Holliday junction resolvase RuvX -
  EL097_RS03585 (NCTC12191_00709) - 673680..673985 (+) 306 WP_003045716.1 DUF1292 domain-containing protein -
  EL097_RS11035 - 674063..674188 (+) 126 WP_257865518.1 hypothetical protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45900.58 Da        Isoelectric Point: 5.3328

>NTDB_id=1120497 EL097_RS03560 WP_003045727.1 669564..670835(+) (cinA) [Streptococcus canis strain NCTC12191]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIAIASQRSDLVILCGGLGPTEDDLTKQT
LAKFLKKDLVFDAQASQKLDDFFASRKQSSRTPNNERQAQLIAGSRPLQNKTGLAVGGLITVDDVTYVVLPGPPSELKPM
VNQELVPFLAHQSSKLYSKVLRFFGIGESQLVTILSDFIENQTDPTIAPYAKTGEVTLRLSTKAKDQTLADKKLAQLEAQ
LLSQKTPDNQPLSDFLYGYGEDNSLARETFELLIKNDKTITAAESLTAGLFQSTLANFSGASQVFNGGFVTYSMEEKAKM
LDIPLEDLKSYGVVSAYTAEKMAGQARLLTGADIGVSLTGVAGPDMLENQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPKNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1120497 EL097_RS03560 WP_003045727.1 669564..670835(+) (cinA) [Streptococcus canis strain NCTC12191]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCCCAATTTTTGTCGGA
GAAAATGGCAGAGCTAGGCATTGATGTCTATTTCCAGACAGCAGTTGGTGATAATGAAGAGCGTCTACTTTCTGTGATTG
CTATTGCTAGTCAACGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGACCTACCGAAGATGATTTAACCAAGCAAACC
CTAGCAAAATTTTTGAAGAAAGATTTGGTTTTTGATGCTCAAGCGAGTCAAAAACTAGATGACTTTTTTGCCAGTCGTAA
GCAGTCATCTCGAACACCAAATAATGAGAGGCAGGCACAACTTATTGCTGGATCAAGACCTTTACAAAATAAGACAGGGT
TGGCAGTTGGTGGTTTGATTACGGTTGATGATGTGACTTACGTTGTTTTACCGGGTCCTCCTAGTGAACTAAAGCCTATG
GTTAATCAGGAATTAGTACCTTTTCTGGCGCATCAGTCTAGCAAACTTTATTCGAAGGTTTTACGCTTTTTTGGGATTGG
CGAGAGTCAATTAGTAACGATTTTATCAGATTTTATTGAAAATCAGACTGATCCCACTATTGCGCCTTATGCTAAGACTG
GGGAGGTCACTCTTCGCTTATCAACAAAAGCTAAGGACCAGACTTTAGCAGATAAGAAACTAGCCCAGTTAGAAGCTCAG
CTATTATCCCAAAAAACTCCTGACAATCAGCCTTTATCAGATTTTCTTTATGGCTATGGAGAGGATAATTCCTTGGCGCG
TGAGACATTTGAGCTCTTAATAAAAAATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAATTTTTCAGGAGCTTCCCAAGTATTCAATGGAGGTTTTGTGACTTATAGCATGGAAGAAAAAGCCAAAATG
CTAGATATTCCTTTAGAAGATTTGAAATCATATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGGACAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTGAGTTTAACAGGTGTTGCTGGGCCAGATATGTTGGAGAACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATTGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTAAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

71.703

98.582

0.707
  cinA Streptococcus mitis NCTC 12261

71.223

98.582

0.702
  cinA Streptococcus pneumoniae TIGR4

70.743

98.582

0.697
  cinA Streptococcus pneumoniae Rx1

70.743

98.582

0.697
  cinA Streptococcus pneumoniae R6

70.743

98.582

0.697
  cinA Streptococcus pneumoniae D39

70.504

98.582

0.695
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

98.818

0.454

Multiple sequence alignment