Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL087_RS08760 Genome accession   NZ_LR134288
Coordinates   1764159..1765427 (-) Length   422 a.a.
NCBI ID   WP_003040629.1    Uniprot ID   A0AAD2YAJ2
Organism   Streptococcus milleri strain NCTC11169     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1759159..1770427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS08725 (NCTC11169_01799) - 1760028..1760339 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  EL087_RS08730 (NCTC11169_01800) ruvX 1760356..1760775 (-) 420 WP_037566947.1 Holliday junction resolvase RuvX -
  EL087_RS08735 (NCTC11169_01801) - 1760775..1761041 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  EL087_RS08740 (NCTC11169_01802) - 1761164..1761721 (-) 558 WP_126408022.1 SP0191 family lipoprotein -
  EL087_RS08745 (NCTC11169_01803) - 1761826..1762395 (-) 570 WP_003040606.1 SP0191 family lipoprotein -
  EL087_RS08750 (NCTC11169_01804) spx 1762481..1762879 (-) 399 WP_003027770.1 transcriptional regulator Spx -
  EL087_RS08755 (NCTC11169_01805) recA 1762966..1764111 (-) 1146 WP_003040800.1 recombinase RecA Machinery gene
  EL087_RS08760 (NCTC11169_01806) cinA 1764159..1765427 (-) 1269 WP_003040629.1 competence/damage-inducible protein A Machinery gene
  EL087_RS08770 (NCTC11169_01807) - 1765697..1766107 (+) 411 WP_126408024.1 helix-turn-helix domain-containing protein -
  EL087_RS08775 (NCTC11169_01808) - 1766158..1766817 (-) 660 WP_003040738.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  EL087_RS08780 (NCTC11169_01809) - 1766822..1767376 (-) 555 WP_003027778.1 DNA-3-methyladenine glycosylase I -
  EL087_RS08785 (NCTC11169_01810) ruvA 1767386..1767976 (-) 591 WP_003040577.1 Holliday junction branch migration protein RuvA -
  EL087_RS08790 (NCTC11169_01811) mutL 1768110..1770056 (-) 1947 WP_126408026.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45764.35 Da        Isoelectric Point: 6.3129

>NTDB_id=1120284 EL087_RS08760 WP_003040629.1 1764159..1765427(-) (cinA) [Streptococcus milleri strain NCTC11169]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLIILTGGLGPTEDDLTKQT
LSKFLNRRLVFDRMATEKLDRFFASRPDYVRTPNNERQAQIVEGSTSLQNETGLAVGGVIEVGGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDTQTDPTIAPYAKTGEVTLRLSTKATSQKEADVKFTRLEKKI
LAVQTFEKQHLADLFYAYGDDNSLGQTAFELLRRAGKTVTAAESLTAGLFQATLANFAGASNVFSGGFVTYSMEEKSRML
GIPLADLEKYGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1120284 EL087_RS08760 WP_003040629.1 1764159..1765427(-) (cinA) [Streptococcus milleri strain NCTC11169]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAACGCCCAATTTTTATCTGA
AAAATTAGCGAGTCTGGGAGTAGATGTGTATTTCCAAACAGCGGTCGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATCGCTCGAAATCGTAGTAATTTGATCATCTTAACTGGAGGATTAGGTCCAACAGAAGATGACTTGACTAAGCAGACT
TTGTCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGATCGCTTCTTCGCAAGTCGACC
GGACTATGTTCGAACACCAAACAATGAGCGACAAGCTCAGATAGTGGAAGGCTCGACCTCTCTCCAAAACGAAACCGGAC
TTGCGGTGGGGGGCGTGATTGAAGTCGGTGGTGTGACTTATGTCGTTCTGCCTGGTCCGCCTAGTGAATTAAAACCTATG
GTAAATAATGAGCTGGTTCCGCTTTTAGCGACTGGCCAAAAATTGTATTCAAGAGTTTTGCGTTTCTTTGGTATTGGTGA
AAGTCAATTAGTAACCCTTTTAGGGGATTTAATTGATACTCAAACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTAACTTTGCGATTGTCCACCAAGGCTACTAGTCAAAAGGAAGCGGATGTTAAGTTTACTCGTTTAGAAAAGAAAATT
TTGGCAGTACAGACTTTTGAGAAACAACATTTAGCTGATCTTTTCTACGCTTATGGAGATGATAATTCTCTGGGACAAAC
AGCTTTTGAACTGCTGAGAAGAGCAGGAAAGACTGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAACTTTGCTGGAGCCTCCAATGTTTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GGCATTCCCTTGGCAGACTTGGAAAAGTATGGGGTGGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACTGCTAGTGACTATGCGGTGAGCTTGACAGGGGTGGCAGGCCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCTTAGCAACCACAGAGGATGTTCAGTCTATTAAGGTTAATATTGCCGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTGCGAAAAACTTTATTAAAAAACGAAAATATGCTATAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.837

99.052

0.751
  cinA Streptococcus mitis NCTC 12261

74.88

99.052

0.742
  cinA Streptococcus pneumoniae Rx1

74.402

99.052

0.737
  cinA Streptococcus pneumoniae TIGR4

74.402

99.052

0.737
  cinA Streptococcus pneumoniae R6

74.402

99.052

0.737
  cinA Streptococcus pneumoniae D39

74.163

99.052

0.735
  cinA Streptococcus mutans UA159

72.577

100

0.727
  cinA Streptococcus suis isolate S10

56.01

98.578

0.552
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

99.052

0.455

Multiple sequence alignment