Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EL087_RS03215 Genome accession   NZ_LR134288
Coordinates   659712..660413 (+) Length   233 a.a.
NCBI ID   WP_003040015.1    Uniprot ID   A0AAD2T8S0
Organism   Streptococcus milleri strain NCTC11169     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 654712..665413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS03195 (NCTC11169_00645) ccpA 655563..656567 (+) 1005 WP_003040018.1 catabolite control protein A Regulator
  EL087_RS03200 (NCTC11169_00646) - 656747..657745 (+) 999 WP_126406804.1 glycosyltransferase family 4 protein -
  EL087_RS03205 (NCTC11169_00647) - 657747..659060 (+) 1314 WP_003039969.1 glycosyltransferase family 4 protein -
  EL087_RS03210 (NCTC11169_00648) - 659087..659428 (+) 342 WP_003040057.1 hypothetical protein -
  EL087_RS03215 (NCTC11169_00649) micA 659712..660413 (+) 702 WP_003040015.1 response regulator YycF Regulator
  EL087_RS03220 (NCTC11169_00650) micB 660406..661758 (+) 1353 WP_126406807.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL087_RS03225 (NCTC11169_00651) vicX 661761..662564 (+) 804 WP_003027672.1 MBL fold metallo-hydrolase Regulator
  EL087_RS03230 (NCTC11169_00652) - 662573..662932 (+) 360 WP_126406809.1 YbaN family protein -
  EL087_RS03235 (NCTC11169_00653) rnc 663306..664004 (+) 699 WP_126406811.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26903.91 Da        Isoelectric Point: 4.6824

>NTDB_id=1120258 EL087_RS03215 WP_003040015.1 659712..660413(+) (micA) [Streptococcus milleri strain NCTC11169]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALEMFEAERPDILILDLMLPEMDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAALTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1120258 EL087_RS03215 WP_003040015.1 659712..660413(+) (micA) [Streptococcus milleri strain NCTC11169]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAGTTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCGACGGTCGCGAAGCGTTAGAAATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCCGAAATGGATGGTTTAGAGGTGGCGCGAACGATTCGGAAAACGAGTAATGTGCCAATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGACAAAGTTATTGGTCTTGAAATCGGTGCGGATGACTATATGACAAAGCCTTTCTCTAATCGTGA
GTTGCAGGCGCGTGTTAAAGCCATTTTGCGGCGGACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCTGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACTGATGCTTTTGTCGTGAAAAAGCATGGCGAAGAATTAGATTTAACACAC
CGTGAGTTTGAATTGCTCCACCATTTGGCAACGCATATCGGGCAAGTGATGACGCGTGAACATCTGCTAGAAACGGTGTG
GGGTTATGATTATTTTGGAGATGTACGGACGGTCGATGTGACAATTCGCCGTTTGAGAGAAAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGTGGCGTTGGATATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.522

98.712

0.361

Multiple sequence alignment