Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL100_RS02695 Genome accession   NZ_LR134285
Coordinates   524217..525239 (-) Length   340 a.a.
NCBI ID   WP_126403665.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 519217..530239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS02655 (NCTC3168_00548) - 519345..520019 (-) 675 WP_224781595.1 CPBP family intramembrane glutamic endopeptidase -
  EL100_RS02660 (NCTC3168_00549) - 520172..521368 (-) 1197 WP_126403669.1 acetate kinase -
  EL100_RS02665 (NCTC3168_00550) comYH 521417..522370 (-) 954 WP_126403668.1 class I SAM-dependent methyltransferase Machinery gene
  EL100_RS02670 (NCTC3168_00551) comGG 522402..522848 (-) 447 WP_126403667.1 competence type IV pilus minor pilin ComGG -
  EL100_RS02675 (NCTC3168_00552) comGF/cglF 522814..523266 (-) 453 WP_048717662.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL100_RS02680 (NCTC3168_00553) comGE 523250..523543 (-) 294 WP_006595134.1 competence type IV pilus minor pilin ComGE -
  EL100_RS02685 comGD/cglD 523509..523934 (-) 426 WP_042507426.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL100_RS02690 (NCTC3168_00555) comYC 523903..524220 (-) 318 WP_023022076.1 competence type IV pilus major pilin ComGC Machinery gene
  EL100_RS02695 (NCTC3168_00556) comYB 524217..525239 (-) 1023 WP_126403665.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL100_RS02700 (NCTC3168_00557) comYA 525181..526122 (-) 942 WP_126403664.1 competence type IV pilus ATPase ComGA Machinery gene
  EL100_RS02705 (NCTC3168_00558) - 526229..526606 (-) 378 WP_048717460.1 DUF1033 family protein -
  EL100_RS02710 (NCTC3168_00559) - 526814..527917 (-) 1104 WP_126403663.1 glycosyl hydrolase family 8 -
  EL100_RS02715 (NCTC3168_00561) - 527926..529236 (-) 1311 Protein_523 glycosyltransferase family 2 protein -
  EL100_RS02720 (NCTC3168_00562) - 529229..529369 (-) 141 WP_006595142.1 hypothetical protein -
  EL100_RS02725 (NCTC3168_00563) - 529379..530167 (-) 789 WP_126403662.1 hypothetical protein -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38940.06 Da        Isoelectric Point: 10.0278

>NTDB_id=1120163 EL100_RS02695 WP_126403665.1 524217..525239(-) (comYB) [Streptococcus australis strain NCTC3168]
MKRDILSWIRRKPKKLSIAKQEHVIELFHNLYSSGFHLSEVIDFLRRSQLVEANFVERMQAGLANGKPLSAILSDLGFSD
QVTTQLALAEQHGNVTLSLEKIRSYLENLTQVRKKLVEVATYPVLLLGFLILIMLGLKNYLLPQLENQNGATRLISIFPQ
YVLLGSVLLTIGVLMLLFLGRRAKRLALISCLARFPFLRPFLQDYLTAFYAREWGSMIAQGLELNQIFPVMQGQRSRLFR
EIGQDLERALARGKSFSDHIQTYPFFKRELALMIEYGEAKSKLGSELEIYADKTWAGFFHRLNKAMNIVQPLVFVFVALM
IVLLYAAMLLPIYENLEVPL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=1120163 EL100_RS02695 WP_126403665.1 524217..525239(-) (comYB) [Streptococcus australis strain NCTC3168]
ATGAAGCGGGACATATTGAGCTGGATCAGGCGCAAGCCGAAAAAATTATCGATTGCTAAGCAAGAACATGTCATTGAGCT
CTTTCACAATCTCTACAGTAGTGGCTTTCATCTATCAGAGGTCATCGACTTTCTTCGGCGCAGTCAATTGGTAGAAGCCA
ATTTTGTTGAAAGAATGCAAGCTGGACTTGCCAACGGAAAGCCCCTGTCAGCCATTCTCTCTGATCTAGGTTTCTCCGAT
CAGGTAACAACTCAATTGGCATTGGCGGAGCAGCATGGAAATGTTACCTTAAGTTTAGAAAAGATCCGTAGCTACTTGGA
AAATCTGACCCAGGTTCGAAAGAAACTAGTTGAGGTGGCGACCTATCCCGTGCTCTTGTTGGGATTTTTGATCTTGATTA
TGCTGGGGCTGAAAAATTATCTCTTGCCTCAGTTGGAGAATCAAAATGGGGCGACACGACTGATTAGTATCTTTCCCCAG
TATGTTTTGTTAGGGAGTGTGTTGCTGACGATTGGAGTTTTGATGCTCCTTTTCCTAGGCCGTCGTGCCAAACGGCTGGC
CCTGATTTCATGTTTGGCTAGATTTCCTTTTCTTCGCCCCTTCTTACAGGATTATCTGACCGCTTTTTATGCTCGAGAAT
GGGGAAGTATGATTGCCCAAGGGTTGGAGCTGAATCAAATTTTTCCTGTGATGCAGGGGCAACGTTCCCGTCTCTTTCGA
GAGATTGGACAGGATTTAGAACGGGCATTGGCTCGTGGCAAGTCTTTTTCTGACCATATTCAGACTTATCCTTTCTTTAA
ACGAGAGCTGGCCCTTATGATTGAATATGGGGAGGCCAAGTCCAAGCTCGGTAGTGAGCTGGAAATCTATGCAGACAAGA
CCTGGGCAGGCTTTTTCCATCGTTTGAACAAGGCCATGAATATCGTTCAACCACTGGTCTTTGTCTTTGTTGCTCTTATG
ATTGTTTTGCTCTATGCAGCCATGTTGCTGCCAATTTATGAAAATTTGGAGGTTCCTTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

61.696

100

0.621
  comGB/cglB Streptococcus mitis NCTC 12261

60.714

98.824

0.6
  comGB/cglB Streptococcus mitis SK321

59.524

98.824

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

58.631

98.824

0.579
  comGB/cglB Streptococcus pneumoniae D39

58.631

98.824

0.579
  comGB/cglB Streptococcus pneumoniae R6

58.631

98.824

0.579
  comGB/cglB Streptococcus pneumoniae TIGR4

58.631

98.824

0.579
  comYB Streptococcus mutans UA159

59.306

93.235

0.553
  comYB Streptococcus mutans UA140

59.306

93.235

0.553
  comGB Lactococcus lactis subsp. cremoris KW2

49.271

100

0.497

Multiple sequence alignment