Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   EL100_RS00355 Genome accession   NZ_LR134285
Coordinates   77976..78653 (-) Length   225 a.a.
NCBI ID   WP_126403987.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC3168     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 72976..83653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL100_RS00335 (NCTC3168_00068) sodA 73332..73937 (-) 606 WP_126403990.1 superoxide dismutase SodA -
  EL100_RS00340 (NCTC3168_00069) holA 74009..75046 (-) 1038 WP_126405032.1 DNA polymerase III subunit delta -
  EL100_RS00345 (NCTC3168_00070) - 75024..75689 (-) 666 WP_126403989.1 DUF805 domain-containing protein -
  EL100_RS00350 (NCTC3168_00071) comEC/celB 75752..77992 (-) 2241 WP_126403988.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL100_RS00355 (NCTC3168_00072) comEA/celA/cilE 77976..78653 (-) 678 WP_126403987.1 helix-hairpin-helix domain-containing protein Machinery gene
  EL100_RS00360 (NCTC3168_00073) - 78757..79500 (-) 744 WP_126403986.1 lysophospholipid acyltransferase family protein -
  EL100_RS00365 (NCTC3168_00074) - 79638..81977 (+) 2340 WP_126403985.1 cation-translocating P-type ATPase -
  EL100_RS00370 (NCTC3168_00075) - 82077..82823 (+) 747 WP_126403984.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  EL100_RS00375 (NCTC3168_00076) - 82813..83091 (+) 279 WP_126403983.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24491.57 Da        Isoelectric Point: 4.5820

>NTDB_id=1120138 EL100_RS00355 WP_126403987.1 77976..78653(-) (comEA/celA/cilE) [Streptococcus australis strain NCTC3168]
METWIEKIKEYKLFLGLAAVGLVIGGLFLFWPKQPPQAPETVISQLEMVDQETSPKEDTSLSSSSQQRSEEKMEPSQEKI
MVDVKGAVRQAGVYELPVGSRVYDAVQKAGGMTDEANSQSVNLAQKLEDESIVYVAKNGEEIAPVASASAGTTSGEKQSK
DGKVNLNTATEAELQTISGIGQKRAQDIIAYREEKGKFQSVDELKNVSGIGQKTLEKLKEHVTVD

Nucleotide


Download         Length: 678 bp        

>NTDB_id=1120138 EL100_RS00355 WP_126403987.1 77976..78653(-) (comEA/celA/cilE) [Streptococcus australis strain NCTC3168]
ATGGAGACGTGGATTGAGAAGATCAAGGAATATAAACTATTTTTAGGCTTGGCTGCTGTGGGCTTGGTAATTGGAGGACT
ATTTCTCTTTTGGCCTAAGCAGCCCCCACAAGCACCGGAAACTGTCATTTCCCAGTTAGAAATGGTGGATCAGGAGACGT
CTCCTAAGGAAGACACAAGCCTCTCTTCCAGCTCTCAGCAGAGGAGTGAGGAAAAGATGGAGCCCTCTCAAGAAAAAATC
ATGGTGGATGTGAAGGGAGCTGTCAGACAAGCGGGGGTTTATGAGCTTCCAGTGGGGAGCCGGGTCTATGACGCAGTGCA
AAAAGCAGGAGGGATGACAGACGAAGCTAACAGCCAATCCGTCAACTTGGCGCAAAAATTGGAGGATGAGTCCATCGTCT
ATGTTGCTAAGAATGGAGAGGAGATAGCGCCTGTTGCATCCGCATCTGCTGGAACGACAAGTGGCGAAAAGCAGTCAAAA
GATGGGAAAGTCAATCTCAATACGGCAACAGAAGCAGAACTACAGACGATTTCTGGGATAGGTCAAAAGCGAGCCCAGGA
TATCATTGCTTATCGAGAGGAAAAAGGAAAATTTCAATCTGTTGATGAATTGAAAAATGTTTCTGGGATCGGCCAAAAGA
CGCTAGAAAAGTTAAAAGAGCATGTTACAGTGGATTAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(161-223)

SLBB domain (SLBB)

(81-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

52.212

100

0.524
  comEA/celA/cilE Streptococcus pneumoniae R6

52.212

100

0.524
  comEA/celA/cilE Streptococcus pneumoniae D39

52.212

100

0.524
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.111

100

0.511
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.222

100

0.502
  comEA/celA/cilE Streptococcus mitis SK321

50.222

100

0.502
  comEA Streptococcus thermophilus LMD-9

46.491

100

0.471
  comEA Lactococcus lactis subsp. cremoris KW2

38.034

100

0.396

Multiple sequence alignment