Detailed information NTG1120137

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL100_RS00350
• Genome accession: NZ_LR134285
• Coordinates: 75752..77992 (-)
• Length: 746 a.a.
• NCBI ID: WP_126403988.1
• Uniprot ID: -
• Organism: Streptococcus australis strain NCTC3168
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 70752..82992

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL100_RS00330 (NCTC3168_00067)	-	71607..73079 (-)	1473	WP_126403991.1	helicase HerA-like domain-containing protein	-
EL100_RS00335 (NCTC3168_00068)	sodA	73332..73937 (-)	606	WP_126403990.1	superoxide dismutase SodA	-
EL100_RS00340 (NCTC3168_00069)	holA	74009..75046 (-)	1038	WP_126405032.1	DNA polymerase III subunit delta	-
EL100_RS00345 (NCTC3168_00070)	-	75024..75689 (-)	666	WP_126403989.1	DUF805 domain-containing protein	-
EL100_RS00350 (NCTC3168_00071)	comEC/celB	75752..77992 (-)	2241	WP_126403988.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL100_RS00355 (NCTC3168_00072)	comEA/celA/cilE	77976..78653 (-)	678	WP_126403987.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL100_RS00360 (NCTC3168_00073)	-	78757..79500 (-)	744	WP_126403986.1	lysophospholipid acyltransferase family protein	-
EL100_RS00365 (NCTC3168_00074)	-	79638..81977 (+)	2340	WP_126403985.1	cation-translocating P-type ATPase	-
EL100_RS00370 (NCTC3168_00075)	-	82077..82823 (+)	747	WP_126403984.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 85962.85 Da
• Isoelectric Point: 9.5916

>NTDB_id=1120137 EL100_RS00350 WP_126403988.1 75752..77992(-) (comEC/celB) [Streptococcus australis strain NCTC3168]
MLQWIRSLHIHLFHLTLPVLALYYWMYTGHWLALIFLLAFLILFRRRYGDKRFLCLIGFLSLFALCFAFRIEQGRRESSD
HRVPRVIQLLPDTIKVNGDALSFRAKSGDRTFQVFYQLQSEEEQAYFKHLDHGLELRIKGELETPTKQRNFMGFDYQAYL
KTQGIHHLLKISHILEKKVAEPSDVIGILSSWRRKALVWVHQHFPQPMSHYMTGLLFGFLDVEFEEMSQLYSNLGIIHLF
ALSGMQVAFFLDAFRRFFLRLGLEQEKVAILLYPFSLLYAGMTGFSVSVVRSLLQKLLAQAGLKGMENMGVTLLLLIVLL
PSSVLTAGGLLSCAYAFILTLTSSEEEKSGIQKVVKESLVLTLGVLPFLIFFFGEYQPWSLPLTFIFSLLFDLLLLPGLS
VVFLLSFFYPLTFWNPFFVWMEKSMEYLARFTSKSLVFGQPSIYFFILLLCLLACLYEMRKVKKWRYLFLLLICSIFALV
KHPLENEITIIDIGQGDSILLRDWRGKTILIDTGGKVDFGQKEGWKKRRSTSNAERTLIPYLKSRGIDRIDHMILTHTDT
DHMGDLEVLAAKVSIQEINISKGSLKKGTFVRLLKRLNLPVKTLEAGDQLTIFDGSAEVLYPVEVGDGSNNDSLVLYGRF
YGWTFLFTGDLEEEGEKTLLARYPQLRVDVLKAGHHGSKGSSHPAFLKQIQAKIALISAGEKNRYQHPHRETLERFKELQ
MTVFRTDQQGAIRFRGWNQWKIETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1120137 EL100_RS00350 WP_126403988.1 75752..77992(-) (comEC/celB) [Streptococcus australis strain NCTC3168]
ATGTTACAGTGGATTAGAAGTCTCCATATTCATTTATTTCATCTCACCCTGCCAGTCTTAGCTCTCTATTATTGGATGTA
CACGGGACACTGGCTCGCTCTAATCTTCCTTCTGGCTTTCCTCATCTTGTTTAGGAGACGCTACGGGGACAAACGATTTT
TGTGCCTCATAGGGTTTCTTTCCCTCTTTGCCCTTTGTTTTGCTTTCCGGATCGAACAAGGAAGACGAGAGTCAAGCGAT
CATAGGGTCCCAAGGGTTATTCAGCTTTTACCGGATACCATCAAGGTGAATGGAGATGCTTTATCTTTTCGTGCGAAGTC
GGGTGACCGTACTTTTCAGGTTTTCTACCAGCTTCAGTCAGAAGAAGAACAAGCTTATTTTAAACACCTGGATCATGGGC
TAGAATTACGGATCAAAGGGGAATTAGAAACACCGACCAAACAGCGTAATTTTATGGGCTTTGATTACCAGGCTTATCTG
AAGACACAAGGGATCCATCATCTTTTGAAAATTAGCCACATCCTTGAAAAGAAAGTAGCTGAGCCTAGCGATGTGATAGG
AATTCTTTCTAGTTGGAGGCGGAAGGCCCTTGTATGGGTCCATCAGCATTTCCCCCAGCCCATGAGTCACTATATGACGG
GCTTGCTTTTTGGTTTTTTAGATGTCGAGTTTGAGGAAATGAGCCAGCTGTATTCGAACTTGGGAATTATCCATCTGTTT
GCCTTGTCAGGCATGCAGGTTGCCTTTTTCTTAGATGCCTTTCGACGATTCTTTCTCCGCCTGGGATTGGAACAGGAGAA
GGTTGCAATCCTCCTCTATCCGTTTTCCCTTCTTTATGCTGGGATGACGGGGTTTTCGGTTTCGGTCGTTCGAAGCCTCT
TACAGAAACTCCTGGCCCAGGCTGGGCTCAAAGGAATGGAAAATATGGGTGTCACCCTTCTTTTATTGATTGTTCTCCTA
CCTTCCTCCGTATTAACTGCTGGAGGTCTCTTATCCTGCGCCTATGCCTTTATATTGACGCTCACCTCTTCCGAAGAGGA
GAAGTCGGGAATCCAAAAAGTCGTCAAGGAAAGTCTGGTGTTAACACTAGGAGTTCTTCCTTTTTTGATATTTTTCTTTG
GAGAATACCAACCCTGGTCTCTTCCTCTAACCTTTATTTTTTCTCTCTTATTTGACCTTCTGTTGTTACCAGGTCTGAGT
GTCGTCTTTCTCCTCTCCTTTTTCTATCCCTTGACCTTCTGGAATCCTTTCTTCGTCTGGATGGAAAAAAGTATGGAGTA
TCTAGCGAGATTCACTAGCAAATCCTTGGTTTTTGGACAGCCAAGCATTTATTTTTTCATCTTGCTTTTGTGCTTGCTAG
CTTGCCTTTATGAGATGCGAAAGGTTAAGAAGTGGAGATATCTTTTTCTACTCTTAATATGCTCTATATTCGCCCTTGTG
AAGCATCCTTTAGAAAATGAGATTACCATCATTGATATTGGTCAAGGAGATAGTATTTTGCTACGTGATTGGCGAGGGAA
AACCATCCTAATTGATACAGGAGGAAAAGTGGACTTTGGCCAAAAGGAGGGATGGAAGAAGCGGAGGTCTACTAGCAATG
CAGAACGGACCTTGATTCCCTATCTCAAGAGTAGGGGGATTGACCGGATTGACCATATGATTCTCACGCATACTGACACA
GATCACATGGGAGATTTGGAAGTACTTGCGGCTAAGGTTAGCATTCAGGAAATCAACATTTCCAAGGGAAGCTTAAAAAA
AGGTACTTTTGTCCGTTTGCTCAAACGCTTAAACCTACCAGTAAAAACGCTGGAGGCTGGTGATCAACTGACGATCTTTG
ATGGGAGTGCAGAAGTTCTCTATCCGGTAGAGGTAGGAGATGGGAGTAATAACGATTCCCTTGTCCTCTATGGGAGGTTT
TATGGTTGGACCTTCCTTTTTACAGGAGATTTAGAAGAAGAGGGGGAAAAGACCTTGTTAGCCCGCTATCCTCAACTGCG
CGTGGATGTATTAAAAGCAGGACACCATGGTTCTAAGGGCTCTTCTCACCCAGCCTTCTTAAAGCAAATCCAAGCAAAAA
TTGCCTTGATATCTGCGGGAGAAAAAAATCGTTACCAGCATCCTCACCGGGAAACCTTGGAACGTTTTAAAGAGTTGCAG
ATGACTGTTTTTCGTACAGATCAGCAAGGAGCGATTCGTTTTAGAGGTTGGAATCAGTGGAAGATTGAAACCGTTCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (32-172)

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (494-700)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	52.996	100	0.534
comEC/celB	Streptococcus mitis SK321	52.855	100	0.534
comEC/celB	Streptococcus pneumoniae TIGR4	52.527	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.261	100	0.527
comEC/celB	Streptococcus pneumoniae D39	52.261	100	0.527
comEC/celB	Streptococcus pneumoniae R6	52.261	100	0.527
comEC	Lactococcus lactis subsp. cremoris KW2	44.758	99.732	0.446