Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL070_RS09645 Genome accession   NZ_LR134284
Coordinates   1829604..1830875 (-) Length   423 a.a.
NCBI ID   WP_111705838.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1824604..1835875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS09615 (NCTC8232_01923) - 1824604..1826163 (-) 1560 WP_111705835.1 DUF2079 domain-containing protein -
  EL070_RS09620 (NCTC8232_01925) - 1826576..1826881 (-) 306 WP_111705836.1 DUF1292 domain-containing protein -
  EL070_RS09625 (NCTC8232_01926) ruvX 1826893..1827312 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  EL070_RS09630 (NCTC8232_01927) - 1827309..1827578 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  EL070_RS09635 (NCTC8232_01928) spx 1827691..1828089 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  EL070_RS09640 (NCTC8232_01929) recA 1828379..1829515 (-) 1137 WP_111705837.1 recombinase RecA Machinery gene
  EL070_RS09645 (NCTC8232_01930) cinA 1829604..1830875 (-) 1272 WP_111705838.1 competence/damage-inducible protein A Machinery gene
  EL070_RS09650 (NCTC8232_01931) - 1830944..1831504 (-) 561 WP_030127533.1 DNA-3-methyladenine glycosylase I -
  EL070_RS09655 (NCTC8232_01932) ruvA 1831514..1832110 (-) 597 WP_002991359.1 Holliday junction branch migration protein RuvA -
  EL070_RS09660 (NCTC8232_01933) - 1832112..1833332 (-) 1221 WP_014612636.1 MDR family MFS transporter -
  EL070_RS09665 (NCTC8232_01934) mutL 1833343..1835325 (-) 1983 WP_011018317.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46049.82 Da        Isoelectric Point: 4.9060

>NTDB_id=1120129 EL070_RS09645 WP_111705838.1 1829604..1830875(-) (cinA) [Streptococcus pyogenes strain NCTC8232]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASHRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSISLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFICLATQNKIESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1120129 EL070_RS09645 WP_111705838.1 1829604..1830875(-) (cinA) [Streptococcus pyogenes strain NCTC8232]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCATCGTAGTGACTTGGTGATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCTCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATCGCATGGCGTTGTTAGTGCTTATACAGCCGAGGGGATGGCGGAGCAAGCAAG
GCTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTTGCCTTGCCACTCAAAATAAGATAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.267

100

0.693
  cinA Streptococcus mitis SK321

69.305

98.582

0.683
  cinA Streptococcus mitis NCTC 12261

68.825

98.582

0.678
  cinA Streptococcus pneumoniae TIGR4

67.866

98.582

0.669
  cinA Streptococcus pneumoniae Rx1

67.866

98.582

0.669
  cinA Streptococcus pneumoniae R6

67.866

98.582

0.669
  cinA Streptococcus pneumoniae D39

67.626

98.582

0.667
  cinA Streptococcus suis isolate S10

53.365

98.345

0.525
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

98.818

0.459

Multiple sequence alignment