Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   EL078_RS08370 Genome accession   NZ_LR134282
Coordinates   1677416..1678807 (-) Length   463 a.a.
NCBI ID   WP_231997657.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1672416..1683807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08355 (NCTC8140_01691) comE/comE2 1673312..1674040 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  EL078_RS09425 comD/comD3 1674658..1675440 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  EL078_RS08365 (NCTC8140_01693) comD/comD3 1676040..1677425 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  EL078_RS08370 (NCTC8140_01694) comD/comD3 1677416..1678807 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  EL078_RS08375 (NCTC8140_01695) - 1678808..1679005 (-) 198 WP_126438119.1 hypothetical protein -
  EL078_RS08380 (NCTC8140_01696) - 1679167..1679460 (-) 294 WP_024344358.1 bacteriocin immunity protein -
  EL078_RS08385 (NCTC8140_01697) - 1679491..1679796 (-) 306 WP_033153382.1 bacteriocin immunity protein -
  EL078_RS08390 (NCTC8140_01698) - 1679816..1680103 (-) 288 WP_164554332.1 DUF3884 family protein -
  EL078_RS08395 (NCTC8140_01699) comC/comC1 1680300..1680455 (+) 156 WP_126438121.1 competence protein Regulator
  EL078_RS08400 (NCTC8140_01700) comD/comD1 1680476..1681747 (-) 1272 WP_231997658.1 sensor histidine kinase Regulator
  EL078_RS08405 (NCTC8140_01701) comE/comE1 1681806..1682537 (-) 732 WP_074567288.1 response regulator transcription factor Regulator
  EL078_RS09430 (NCTC8140_01704) - 1683400..1683504 (-) 105 WP_231997659.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 463 a.a.        Molecular weight: 53303.27 Da        Isoelectric Point: 6.4031

>NTDB_id=1119996 EL078_RS08370 WP_231997657.1 1677416..1678807(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
MRMIFMEVLGVLMNFSSFLILGVLFQQITKNKLTLGEWIFGILFIQIFSLGLAYSFVYRFNIAVLITKDVAPAACLMLIS
YHHNPRISFRYHLFYALYPINVHIILQRVYAYLLMMLFSIEITPRFDTAPIVTIIATIIAIFIPPVLYYLISKWLNIDIS
NVRKTLKNYLSSGVLTIVNILMVVYYFGNDYLALEVPSDSPILKIIVRTGAFIYLFLLFAFLFYLNFRHGQEQKNELLRN
QEMELKALENYSKHVESLYQEVRSFRHDYANVLMSLKVGIDQGDLDNIKKIYEEITADSAKLVKNNKFDLTRLANISDSA
VKSLMSAKFLEAENRSIEISLEVAEPMKNPKIPLISYIRILSILFDNAIEAALESENPKIAVANFYQDGDFVFIIENSTK
EKSVDLTKIFERGYSTKGENRGLGLATLVDFQDDYENLSVETSSFDYKFTQVVRVYEGEIKCS

Nucleotide


Download         Length: 1392 bp        

>NTDB_id=1119996 EL078_RS08370 WP_231997657.1 1677416..1678807(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
ATGCGAATGATTTTTATGGAAGTATTAGGGGTTCTGATGAATTTTTCGTCTTTTTTAATACTAGGAGTTTTATTTCAGCA
GATAACTAAAAATAAACTCACTTTAGGAGAGTGGATTTTTGGAATATTATTTATTCAAATTTTTTCTCTTGGGCTTGCCT
ACAGTTTTGTCTATCGTTTTAATATTGCTGTTCTAATAACTAAGGATGTTGCGCCAGCAGCCTGTTTGATGTTAATTTCA
TATCATCATAATCCTAGAATTAGTTTTAGGTATCATCTTTTTTATGCTTTATATCCTATTAATGTTCACATAATTTTACA
AAGAGTATATGCCTATTTATTAATGATGCTCTTTTCAATTGAAATTACTCCTCGGTTTGACACTGCGCCGATAGTTACAA
TTATTGCTACAATTATCGCTATTTTTATACCGCCAGTTTTATATTATTTGATATCAAAGTGGCTTAATATTGATATTTCA
AATGTTCGAAAAACATTAAAAAATTATCTAAGTTCAGGAGTTTTGACGATTGTTAATATTTTAATGGTGGTTTATTATTT
CGGAAATGATTATCTTGCTTTAGAGGTACCATCAGATTCTCCAATTTTAAAAATAATTGTGAGAACTGGTGCTTTTATCT
ATTTATTCCTCCTTTTTGCATTCCTCTTCTATCTTAATTTCCGTCATGGGCAGGAGCAGAAAAATGAGCTGCTCCGCAAT
CAGGAAATGGAGCTTAAAGCTTTGGAAAATTATAGTAAACATGTGGAGAGTTTGTACCAAGAAGTACGCAGTTTTCGTCA
CGATTACGCTAATGTTTTGATGAGTTTGAAGGTTGGGATAGATCAAGGTGACCTTGATAATATCAAGAAAATTTACGAAG
AAATCACGGCTGACTCAGCGAAGTTGGTCAAAAACAATAAGTTTGACTTGACGCGACTAGCAAATATTTCAGACAGTGCC
GTCAAAAGCCTTATGTCGGCTAAATTTTTGGAGGCTGAAAATCGAAGTATTGAAATTAGTCTAGAAGTGGCAGAGCCGAT
GAAAAATCCCAAAATCCCACTGATTTCTTACATTCGAATTTTATCAATTCTGTTTGACAATGCCATCGAGGCTGCTTTAG
AGTCAGAAAATCCCAAAATCGCAGTAGCGAATTTTTACCAAGATGGAGATTTTGTGTTTATCATTGAAAATTCAACTAAG
GAAAAATCAGTGGATTTAACTAAGATTTTTGAGCGTGGGTACTCAACAAAAGGTGAGAATCGCGGTCTGGGTCTTGCGAC
ATTGGTTGATTTTCAGGATGATTATGAGAATTTGTCGGTTGAAACCAGCAGTTTTGATTACAAATTTACGCAAGTTGTGA
GAGTTTATGAGGGGGAAATTAAGTGCTCTTGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(358-453)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

68.64

98.488

0.676
  comD/comD2 Streptococcus equinus JB1

76.101

68.683

0.523

Multiple sequence alignment