Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   EL078_RS08365 Genome accession   NZ_LR134282
Coordinates   1676040..1677425 (-) Length   461 a.a.
NCBI ID   WP_231997656.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671040..1682425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08340 (NCTC8140_01688) rpe 1671480..1672142 (-) 663 WP_024343526.1 ribulose-phosphate 3-epimerase -
  EL078_RS08345 (NCTC8140_01689) rsgA 1672149..1673021 (-) 873 WP_126438118.1 ribosome small subunit-dependent GTPase A -
  EL078_RS08355 (NCTC8140_01691) comE/comE2 1673312..1674040 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  EL078_RS09425 comD/comD3 1674658..1675440 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  EL078_RS08365 (NCTC8140_01693) comD/comD3 1676040..1677425 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  EL078_RS08370 (NCTC8140_01694) comD/comD3 1677416..1678807 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  EL078_RS08375 (NCTC8140_01695) - 1678808..1679005 (-) 198 WP_126438119.1 hypothetical protein -
  EL078_RS08380 (NCTC8140_01696) - 1679167..1679460 (-) 294 WP_024344358.1 bacteriocin immunity protein -
  EL078_RS08385 (NCTC8140_01697) - 1679491..1679796 (-) 306 WP_033153382.1 bacteriocin immunity protein -
  EL078_RS08390 (NCTC8140_01698) - 1679816..1680103 (-) 288 WP_164554332.1 DUF3884 family protein -
  EL078_RS08395 (NCTC8140_01699) comC/comC1 1680300..1680455 (+) 156 WP_126438121.1 competence protein Regulator
  EL078_RS08400 (NCTC8140_01700) comD/comD1 1680476..1681747 (-) 1272 WP_231997658.1 sensor histidine kinase Regulator

Sequence

Protein


Download         Length: 461 a.a.        Molecular weight: 52951.14 Da        Isoelectric Point: 7.3870

>NTDB_id=1119995 EL078_RS08365 WP_231997656.1 1676040..1677425(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
MLLILQYIVLLLSNFIGIVILGILFQQITKVKVTLLEWILIIIFVQTGSFLMDPQKYPMVILVLIKDISVIFCLIALSFR
HNPKIGIRYHIFYALYPINLYMILQGVYCYIILAIFSIKLTSLAMTSPSLEIIIGTITAVIIPPIFYYLISKWLNIDISN
VRKTLKNYLSARALRFVNVLLLLFYPGMECFAAIAPFEKMSTNRNIYRLTILIYFVLLFAFLFYLNFRHGQEQKNELLRN
QEMELKALENYSKHVESLYQEVRSFRHDYANVLMSLKVGIDQGDLDNIKKIYEEITADSAKLVKNNKFDLTRLANISDSA
VKSLMSAKFLEAENRSIEISLEVAEPMKNPAIPLISYIRILSILFDNAVEGALESDESKIAVANFYQDGHFVFIIENSTR
KKSVDLSNIFQRGYSTKGENRGLGLATLVDFQDDYENLSVETSSSDYTFTQVVRIYEGDSR

Nucleotide


Download         Length: 1386 bp        

>NTDB_id=1119995 EL078_RS08365 WP_231997656.1 1676040..1677425(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
GTGCTCTTGATTTTACAGTATATCGTTTTGTTACTTTCTAATTTTATAGGGATTGTTATATTAGGGATTTTGTTTCAACA
AATAACAAAAGTTAAGGTAACACTTTTAGAGTGGATATTGATAATAATATTTGTTCAAACTGGTTCATTTTTAATGGATC
CTCAGAAATATCCAATGGTTATTTTAGTGCTAATAAAAGATATTTCAGTGATTTTTTGTTTAATAGCACTTTCATTTCGC
CATAATCCTAAAATAGGGATAAGATATCATATTTTTTATGCTTTGTATCCGATTAACCTTTATATGATTTTACAAGGAGT
TTATTGTTATATTATATTGGCGATTTTTTCAATAAAATTGACCTCTCTTGCAATGACTTCACCATCGTTAGAAATTATAA
TTGGTACAATAACTGCAGTTATTATTCCACCAATTTTTTACTATCTGATATCAAAGTGGCTTAACATTGATATTTCAAAT
GTCAGAAAAACGCTCAAGAATTATCTTAGTGCAAGAGCGCTTAGATTCGTCAATGTTTTATTATTACTTTTTTATCCAGG
AATGGAGTGTTTTGCGGCGATAGCACCGTTTGAAAAAATGTCAACGAATAGAAATATTTATAGGTTGACCATCCTTATTT
ACTTCGTTCTCCTTTTTGCCTTCCTCTTCTATCTTAACTTCCGTCACGGGCAGGAGCAGAAAAACGAGCTGCTCCGCAAT
CAGGAAATGGAGCTTAAAGCTTTGGAAAATTATAGTAAACATGTGGAGAGTTTGTACCAAGAAGTGCGCAGTTTTCGTCA
CGATTATGCCAACGTTTTGATGAGTTTGAAGGTCGGCATTGATCAAGGTGATCTTGATAATATCAAGAAAATTTACGAAG
AAATCACGGCTGACTCAGCGAAGTTGGTCAAAAACAATAAGTTTGATTTGACGCGACTAGCAAATATTTCAGACAGCGCC
GTCAAAAGTCTCATGTCAGCCAAATTTTTGGAGGCTGAAAATCGAAGTATTGAAATTAGTCTAGAAGTGGCAGAGCCAAT
GAAAAATCCAGCTATTCCACTGATTTCTTACATTCGAATTTTATCAATTCTGTTTGACAATGCCGTCGAAGGGGCCTTAG
AGTCAGATGAGTCCAAAATCGCAGTAGCGAATTTTTACCAAGATGGACATTTTGTGTTTATCATTGAAAATTCAACTAGG
AAAAAATCTGTGGATTTATCCAATATTTTCCAGCGTGGGTACTCAACAAAAGGTGAGAATCGCGGTCTGGGGCTTGCGAC
ATTGGTTGATTTTCAGGATGATTACGAGAATTTGTCAGTTGAAACCAGCAGTTCAGATTACACATTCACACAAGTAGTGA
GAATATATGAGGGAGATAGTAGATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(358-455)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

82.533

99.349

0.82
  comD/comD2 Streptococcus equinus JB1

74.603

68.33

0.51

Multiple sequence alignment