Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   EL078_RS09425 Genome accession   NZ_LR134282
Coordinates   1674658..1675440 (-) Length   260 a.a.
NCBI ID   WP_231997655.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1669658..1680440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08335 (NCTC8140_01687) - 1670855..1671487 (-) 633 WP_126438117.1 thiamine diphosphokinase -
  EL078_RS08340 (NCTC8140_01688) rpe 1671480..1672142 (-) 663 WP_024343526.1 ribulose-phosphate 3-epimerase -
  EL078_RS08345 (NCTC8140_01689) rsgA 1672149..1673021 (-) 873 WP_126438118.1 ribosome small subunit-dependent GTPase A -
  EL078_RS08355 (NCTC8140_01691) comE/comE2 1673312..1674040 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  EL078_RS09425 comD/comD3 1674658..1675440 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  EL078_RS08365 (NCTC8140_01693) comD/comD3 1676040..1677425 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  EL078_RS08370 (NCTC8140_01694) comD/comD3 1677416..1678807 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  EL078_RS08375 (NCTC8140_01695) - 1678808..1679005 (-) 198 WP_126438119.1 hypothetical protein -
  EL078_RS08380 (NCTC8140_01696) - 1679167..1679460 (-) 294 WP_024344358.1 bacteriocin immunity protein -
  EL078_RS08385 (NCTC8140_01697) - 1679491..1679796 (-) 306 WP_033153382.1 bacteriocin immunity protein -
  EL078_RS08390 (NCTC8140_01698) - 1679816..1680103 (-) 288 WP_164554332.1 DUF3884 family protein -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 29891.98 Da        Isoelectric Point: 4.7714

>NTDB_id=1120006 EL078_RS09425 WP_231997655.1 1674658..1675440(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
MNRNIYRAVIFIYFILLFIFLFYLNFRHGQEQKEELLRNQEMELKALENYSKHVESLYQEVRSFRHDYANVLMSLKVGID
QGDLDNIKKIYEEITADSAKLVKNNKFDLTRLANISDSAVKSLMSAKFLEAENRGIEISLEVAEPMKNPAIPLISYIRIL
SILFDNAIEAALESENPKIAVANFYQDGDFVFIIENSTREKSVDLSKIFQRGYSTKGENRGLGLATLVDFQDDYENLSVE
TSSLDYKFTQVVRVYEGGNG

Nucleotide


Download         Length: 783 bp        

>NTDB_id=1120006 EL078_RS09425 WP_231997655.1 1674658..1675440(-) (comD/comD3) [Streptococcus equinus strain NCTC8140]
ATGAATAGAAATATTTATAGGGCTGTTATTTTTATTTACTTCATCCTTCTTTTCATTTTCCTCTTTTACCTCAACTTCCG
TCATGGGCAGGAGCAGAAAGAAGAATTGCTCCGCAATCAGGAAATGGAGCTTAAAGCTTTGGAAAATTATAGTAAACATG
TGGAGAGTTTGTACCAAGAAGTGCGCAGTTTTCGTCACGATTATGCCAACGTTTTGATGAGTTTGAAGGTCGGCATTGAT
CAAGGTGACCTTGATAATATCAAGAAAATTTACGAAGAAATCACGGCTGACTCAGCAAAGCTGGTCAAAAACAATAAGTT
TGATTTGACGCGATTAGCAAATATTTCAGACAGTGCCGTCAAAAGTCTCATGTCGGCTAAATTTTTGGAGGCTGAAAATC
GTGGCATTGAAATCAGTTTAGAAGTGGCAGAGCCAATGAAAAATCCAGCTATTCCACTGATTTCTTACATTCGAATTTTA
TCAATTCTGTTTGACAATGCTATCGAGGCTGCTTTGGAGTCGGAAAATCCAAAAATCGCAGTAGCGAATTTTTATCAAGA
CGGAGATTTTGTGTTTATCATTGAAAATTCGACTAGGGAAAAATCTGTGGACTTGAGTAAGATTTTTCAGCGTGGGTACT
CAACAAAAGGTGAGAATCGCGGACTTGGACTTGCAACGCTTGTTGATTTTCAGGATGATTATGAAAATTTGTCAGTTGAA
ACCAGCAGTCTCGATTACAAATTTACGCAAGTTGTGAGAGTTTATGAGGGGGGAAATGGCTAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(157-252)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

87.938

98.846

0.869
  comD/comD2 Streptococcus equinus JB1

83.594

98.462

0.823
  comD/comD1 Streptococcus equinus JB1

51.082

88.846

0.454
  comD/blpH Streptococcus mutans UA159

42.742

95.385

0.408

Multiple sequence alignment