Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   EL078_RS08355 Genome accession   NZ_LR134282
Coordinates   1673312..1674040 (-) Length   242 a.a.
NCBI ID   WP_033153377.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1668312..1679040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08325 (NCTC8140_01685) - 1668647..1669588 (-) 942 WP_024343528.1 3'-5' exoribonuclease YhaM family protein -
  EL078_RS08330 (NCTC8140_01686) rmuC 1669578..1670792 (-) 1215 WP_371851905.1 DNA recombination protein RmuC -
  EL078_RS08335 (NCTC8140_01687) - 1670855..1671487 (-) 633 WP_126438117.1 thiamine diphosphokinase -
  EL078_RS08340 (NCTC8140_01688) rpe 1671480..1672142 (-) 663 WP_024343526.1 ribulose-phosphate 3-epimerase -
  EL078_RS08345 (NCTC8140_01689) rsgA 1672149..1673021 (-) 873 WP_126438118.1 ribosome small subunit-dependent GTPase A -
  EL078_RS08355 (NCTC8140_01691) comE/comE2 1673312..1674040 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  EL078_RS09425 comD/comD3 1674658..1675440 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  EL078_RS08365 (NCTC8140_01693) comD/comD3 1676040..1677425 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  EL078_RS08370 (NCTC8140_01694) comD/comD3 1677416..1678807 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  EL078_RS08375 (NCTC8140_01695) - 1678808..1679005 (-) 198 WP_126438119.1 hypothetical protein -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28297.51 Da        Isoelectric Point: 6.4962

>NTDB_id=1119994 EL078_RS08355 WP_033153377.1 1673312..1674040(-) (comE/comE2) [Streptococcus equinus strain NCTC8140]
MIDIYVLEDNVNQQFRIERMIDELLDENQWDYRHFEIFSEPSHFPNFVEESCPQIFFLDIDINGDNKKGIEVAKKIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKSDEDSSIKINLKNCLRKVIENQALTMPQEFFVFENNKATIRIPMDEILY
FETAESHRLKLVTKSGQRNFYGSIKEVMAANQTFFRSHKSYLINLDNVVCLDKKNSLVHFVGGQSCLVSKKYIKELKLKI
GV

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1119994 EL078_RS08355 WP_033153377.1 1673312..1674040(-) (comE/comE2) [Streptococcus equinus strain NCTC8140]
ATGATTGACATCTATGTATTGGAGGACAATGTAAATCAGCAATTTCGGATTGAAAGGATGATTGATGAACTACTTGATGA
AAATCAGTGGGACTATCGTCATTTTGAAATATTTAGTGAGCCGTCTCATTTTCCAAATTTTGTTGAGGAATCTTGCCCAC
AAATTTTTTTCTTAGATATTGATATCAATGGTGATAATAAAAAGGGAATTGAAGTCGCTAAGAAAATTAGGGAGAAATCT
AGAACAGCTACGATTGTTTTTGTTACGACGCATTCTGAGTTTATGTTGTTGACTTACCGAGCACAGGTTAGTGCACTTGA
TTTTATTGATAAGTCAGATGAAGACAGTTCGATAAAAATTAATTTAAAAAATTGTTTGCGAAAGGTCATCGAAAATCAGG
CTCTTACGATGCCACAGGAATTTTTTGTATTTGAAAATAATAAAGCTACTATTCGTATTCCGATGGATGAAATTCTTTAT
TTTGAAACAGCTGAAAGTCATCGACTGAAGTTGGTTACAAAGTCGGGACAACGTAATTTTTATGGTTCAATCAAAGAAGT
AATGGCTGCTAATCAGACCTTTTTTAGAAGCCACAAATCGTATCTGATTAATCTTGATAATGTTGTGTGCTTAGATAAAA
AGAATAGTTTGGTGCATTTTGTCGGTGGTCAATCTTGCCTTGTTTCAAAGAAATACATTAAAGAATTAAAGTTGAAAATA
GGTGTTTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

LytTr DNA-binding domain (LytTR)

(149-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

74.167

99.174

0.736
  comE/comE1 Streptococcus equinus JB1

44.118

98.347

0.434
  comE/blpR Streptococcus mutans UA159

40.164

100

0.405
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.367

100

0.388
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.367

100

0.388

Multiple sequence alignment