Detailed information NTG1119919

Bioinformatically predicted

Overview

• Name: comGA/cglA/cilD
• Type: Machinery gene
• Locus tag: EL076_RS09140
• Genome accession: NZ_LR134275
• Coordinates: 1805927..1806868 (-)
• Length: 313 a.a.
• NCBI ID: WP_126430079.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1807052..1807516	1805927..1806868	flank	184

Gene organization within MGE regions

Location: 1805927..1807516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS09140 (NCTC12167_01803)	comGA/cglA/cilD	1805927..1806868 (-)	942	WP_126430079.1	competence type IV pilus ATPase ComGA	Machinery gene
EL076_RS09145 (NCTC12167_01804)	tnpA	1807052..1807516 (-)	465	WP_002883780.1	IS200/IS605 family transposase	-

Sequence

Protein

• Length: 313 a.a.
• Molecular weight: 35244.24 Da
• Isoelectric Point: 5.9272

>NTDB_id=1119919 EL076_RS09140 WP_126430079.1 1805927..1806868(-) (comGA/cglA/cilD) [Streptococcus vestibularis strain NCTC12167]
MITEFAKEIIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRVLHSERRELTYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide

• Length: 942 bp

>NTDB_id=1119919 EL076_RS09140 WP_126430079.1 1805927..1806868(-) (comGA/cglA/cilD) [Streptococcus vestibularis strain NCTC12167]
ATGATAACAGAATTTGCTAAGGAAATAATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTTGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTAGGTGAGAAGCGTAGGAGTCAATTGGGCTCTTGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATTCGTGT
TCTTCATTCTGAACGAAGAGAGCTAACTTACTGGAATCAAGGAATTCAGCCTATTAAGGATGCATTGGATTATCGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCTATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTCGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.916	99.361	0.655
comYA	Streptococcus mutans UA159	65.176	100	0.652
comYA	Streptococcus mutans UA140	65.176	100	0.652
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae R6	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	64.63	99.361	0.642
comGA/cglA/cilD	Streptococcus pneumoniae D39	64.63	99.361	0.642
comYA	Streptococcus gordonii str. Challis substr. CH1	62.939	100	0.629
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	60.577	99.681	0.604
comGA	Lactococcus lactis subsp. cremoris KW2	51.125	99.361	0.508
comGA	Latilactobacillus sakei subsp. sakei 23K	40.794	88.498	0.361