Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   EL076_RS09135 Genome accession   NZ_LR134275
Coordinates   1804945..1806045 (-) Length   366 a.a.
NCBI ID   WP_126430077.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1799945..1811045
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS10515 - 1800120..1800590 (-) 471 WP_082901122.1 CAAX protease -
  EL076_RS09095 (NCTC12167_01794) - 1800577..1800774 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  EL076_RS09100 (NCTC12167_01795) - 1801002..1802195 (-) 1194 WP_064520007.1 acetate kinase -
  EL076_RS09105 (NCTC12167_01796) comYH 1802252..1803208 (-) 957 WP_126430075.1 class I SAM-dependent methyltransferase Machinery gene
  EL076_RS09110 (NCTC12167_01797) comGG 1803253..1803570 (-) 318 WP_003092009.1 competence type IV pilus minor pilin ComGG -
  EL076_RS09115 (NCTC12167_01798) comYF 1803548..1803985 (-) 438 WP_003091908.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL076_RS09120 (NCTC12167_01799) comGE 1803972..1804202 (-) 231 WP_003095891.1 competence type IV pilus minor pilin ComGE -
  EL076_RS09125 (NCTC12167_01800) comYD 1804234..1804662 (-) 429 WP_253665936.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL076_RS09130 (NCTC12167_01801) comYC 1804622..1804948 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  EL076_RS09135 (NCTC12167_01802) comYB 1804945..1806045 (-) 1101 WP_126430077.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL076_RS09140 (NCTC12167_01803) comGA/cglA/cilD 1805927..1806868 (-) 942 WP_126430079.1 competence type IV pilus ATPase ComGA Machinery gene
  EL076_RS09145 (NCTC12167_01804) tnpA 1807052..1807516 (-) 465 WP_002883780.1 IS200/IS605 family transposase -
  EL076_RS09150 (NCTC12167_01805) - 1807715..1808077 (-) 363 WP_126430081.1 DUF1033 family protein -
  EL076_RS09155 (NCTC12167_01806) - 1808250..1809986 (-) 1737 WP_126430083.1 ABC transporter ATP-binding protein -
  EL076_RS09160 (NCTC12167_01807) - 1810004..1810762 (-) 759 WP_126430085.1 hypothetical protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41659.80 Da        Isoelectric Point: 10.1478

>NTDB_id=1119918 EL076_RS09135 WP_126430077.1 1804945..1806045(-) (comYB) [Streptococcus vestibularis strain NCTC12167]
MPVKISKAIRQPAGTNSWKAWLNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDKMFASVGFSDNIVTQIALADKHGNLLGSLTKIEAYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTIRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFIIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1119918 EL076_RS09135 WP_126430077.1 1804945..1806045(-) (comYB) [Streptococcus vestibularis strain NCTC12167]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTCTTCAAACAACTTCTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACAAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCATGGTAATCTTCTAGGAAGTTTAACCAAGATTGAAGCCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTTCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAATTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTATCTATGGGTCAAACGCCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTATCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGGATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGATCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AGCTATCCTTGATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTATTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.312

93.716

0.481
  comGB/cglB Streptococcus mitis NCTC 12261

50.442

92.623

0.467
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

44.985

89.891

0.404

Multiple sequence alignment