Detailed information NTG1119903

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: EL076_RS07655
• Genome accession: NZ_LR134275
• Coordinates: 1526876..1527571 (-)
• Length: 231 a.a.
• NCBI ID: WP_003093743.1
• Uniprot ID: A0AAW7QFH2
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1521876..1532571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS07640 (NCTC12167_01501)	-	1522687..1523232 (-)	546	WP_003093731.1	GNAT family N-acetyltransferase	-
EL076_RS07645 (NCTC12167_01502)	-	1523298..1524560 (-)	1263	WP_003093180.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL076_RS07650 (NCTC12167_01503)	comEC/celB	1524646..1526886 (-)	2241	WP_126429930.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL076_RS07655 (NCTC12167_01504)	comEA	1526876..1527571 (-)	696	WP_003093743.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL076_RS07660 (NCTC12167_01505)	-	1527679..1528434 (-)	756	WP_003096426.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EL076_RS07665 (NCTC12167_01506)	-	1528564..1529499 (+)	936	WP_003096423.1	polysaccharide deacetylase family protein	-
EL076_RS07670 (NCTC12167_01507)	-	1529549..1530313 (+)	765	WP_003096421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL076_RS07675 (NCTC12167_01508)	-	1530317..1530586 (+)	270	WP_003096419.1	GIY-YIG nuclease family protein	-
EL076_RS07685 (NCTC12167_01509)	-	1530967..1531473 (-)	507	WP_126429932.1	hypothetical protein	-

Sequence

Protein

• Length: 231 a.a.
• Molecular weight: 24588.56 Da
• Isoelectric Point: 4.7187

>NTDB_id=1119903 EL076_RS07655 WP_003093743.1 1526876..1527571(-) (comEA) [Streptococcus vestibularis strain NCTC12167]
MKEKIIDYVNNNRLFVSIIGVLMMVFCFFLWMTCGAGNSMEAETSYTDVTTLSTSSSKEGSKSLTEVSSQSQTEGSEKVK
SKVTVDVKGAVVKPGVYTLKVSARVTDAIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQSDTGQVSNKG
GQAVSKNGKINLNTATSEQLQTISGIGAKRAEDIVAYRESHGGFQSVGDLKNVSGIGDKTLDKIRESIYVA

Nucleotide

• Length: 696 bp

>NTDB_id=1119903 EL076_RS07655 WP_003093743.1 1526876..1527571(-) (comEA) [Streptococcus vestibularis strain NCTC12167]
GTGAAGGAAAAGATTATAGACTATGTTAACAATAATCGTCTATTTGTGAGTATCATTGGTGTGCTGATGATGGTTTTCTG
CTTCTTTCTGTGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCAGAGACGTCTTATACAGATGTGACAACATTGTCAA
CCTCCTCATCCAAAGAAGGGTCAAAATCACTTACGGAAGTGTCTTCTCAGTCACAAACTGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAAGCCAGGTGTATATACGCTAAAAGTAAGCGCTAGGGTGACAGA
TGCCATTCAGGAAGCTGGAGGAATGACAGAGGATGCAGACGCTAAGAGTGTTAATTTGGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGACGAGAATGTTTCTGTTCTTGATCAATCAGATACTGGTCAGGTCTCTAACAAAGGA
GGGCAGGCTGTATCTAAGAATGGCAAAATTAACTTAAATACAGCGACCTCAGAGCAGTTACAAACTATTTCTGGAATTGG
TGCCAAGAGGGCAGAGGATATTGTCGCTTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGGTGACCTGAAAAATGTTT
CAGGCATTGGTGATAAAACGTTAGATAAAATCAGAGAGTCCATCTATGTGGCTTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (85-138)

• Helix-hairpin-helix motif (HHH_3) (166-228)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	88.312	100	0.883
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	40.175	99.134	0.398
comEA/celA/cilE	Streptococcus pneumoniae D39	39.056	100	0.394
comEA/celA/cilE	Streptococcus pneumoniae Rx1	39.056	100	0.394
comEA/celA/cilE	Streptococcus pneumoniae R6	39.056	100	0.394
comEA/celA/cilE	Streptococcus mitis SK321	39.301	99.134	0.39
comEA	Latilactobacillus sakei subsp. sakei 23K	35.246	100	0.372
comEA/celA/cilE	Streptococcus mitis NCTC 12261	37.281	98.701	0.368