Detailed information NTG1119902

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: EL076_RS07650
• Genome accession: NZ_LR134275
• Coordinates: 1524646..1526886 (-)
• Length: 746 a.a.
• NCBI ID: WP_126429930.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis strain NCTC12167
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1519646..1531886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL076_RS07630 (NCTC12167_01499)	-	1520510..1521370 (-)	861	WP_003096442.1	methionyl aminopeptidase	-
EL076_RS07635 (NCTC12167_01500)	spxR	1521414..1522694 (-)	1281	WP_003094415.1	CBS-HotDog domain-containing transcription factor SpxR	-
EL076_RS07640 (NCTC12167_01501)	-	1522687..1523232 (-)	546	WP_003093731.1	GNAT family N-acetyltransferase	-
EL076_RS07645 (NCTC12167_01502)	-	1523298..1524560 (-)	1263	WP_003093180.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EL076_RS07650 (NCTC12167_01503)	comEC/celB	1524646..1526886 (-)	2241	WP_126429930.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EL076_RS07655 (NCTC12167_01504)	comEA	1526876..1527571 (-)	696	WP_003093743.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL076_RS07660 (NCTC12167_01505)	-	1527679..1528434 (-)	756	WP_003096426.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EL076_RS07665 (NCTC12167_01506)	-	1528564..1529499 (+)	936	WP_003096423.1	polysaccharide deacetylase family protein	-
EL076_RS07670 (NCTC12167_01507)	-	1529549..1530313 (+)	765	WP_003096421.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL076_RS07675 (NCTC12167_01508)	-	1530317..1530586 (+)	270	WP_003096419.1	GIY-YIG nuclease family protein	-
EL076_RS07685 (NCTC12167_01509)	-	1530967..1531473 (-)	507	WP_126429932.1	hypothetical protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84940.88 Da
• Isoelectric Point: 9.8301

>NTDB_id=1119902 EL076_RS07650 WP_126429930.1 1524646..1526886(-) (comEC/celB) [Streptococcus vestibularis strain NCTC12167]
MWLKKSPINLFSLALLIVALYFTIFVSNFYAIGAFVFFMVCFLKHHWKNMAALKLVGLVGGFFLIYFLFLHHRAIMQDKQ
VPAEIHQVTLVADTLSVNGEQLSAIGKSNGQTYRVFYRLKSEKEQYFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQSIYRIAQIERLDHIVTPKSISPIDFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYSLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLLFLV
LPHFLLTVGGVLSCSYAFLLCLFDFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPILT
VLFTLSGLVIFSQINPLFEWMETFLTWIQYWIGQPLILGKPSLFQFGLMIVVLVLLFDFWKKPQFRISLLMIFSLLMIWV
KHPLINEVTVVDVGQGDSIFLRSMKGKTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFAKRLRFLKRPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMSSYPNLKVSVLKAGHHGSKGSSSEAFLDQLEPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFKLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1119902 EL076_RS07650 WP_126429930.1 1524646..1526886(-) (comEC/celB) [Streptococcus vestibularis strain NCTC12167]
ATGTGGCTTAAAAAATCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGGCTTTTGTCTTTTTTATGGTCTGTTTTTTGAAGCATCATTGGAAGAATATGGCAGCTCTAA
AGTTGGTGGGACTTGTTGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCACCACAGAGCTATCATGCAAGATAAGCAA
GTTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCAATTATCAGCAATCGGTAA
GTCAAATGGTCAAACCTATCGGGTCTTTTACCGGTTAAAATCTGAGAAGGAGCAGTATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGAAAAATAAAGCTATCCTCGGCAACAGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGAGCATTTATAGGATTGCTCAGATTGAGCGTCTGGATCATATCGTAACCCCAAAATCGATATCTCCAAT
AGATTTTTTCCATCAATTGAGGAGGAGGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTATATGA
CAGGACTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGTCAACTCTACACCAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTTCGTTTGGGTCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATAGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTTTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTGCTTCTATTATTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTATTGTGTTTATTTGATTTTGAGGA
GATGCCGTCTTTTAAAAAGTCAATCTATATGAGTTTGGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTCGATAGCTTTCTCTTACCTATCTTAACA
GTACTTTTTACACTTTCAGGACTGGTAATCTTTTCTCAAATTAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATACTGGATAGGCCAGCCTTTAATTCTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGATCTGGGTT
AAACATCCTTTGATCAATGAGGTGACGGTGGTTGACGTTGGTCAAGGAGACAGTATTTTTTTAAGGAGTATGAAAGGTAA
GACGATCCTGATAGACGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACAGATACA
GACCATATTGGTGATTTGGAGGAAGTAGCTAAACGGTTTAAGATTAAGGAAATTTGTGTCAGTCAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTCTTCGATTTCTTAAACGTCCCGTTCGCACCTTAAAGGCTGGTGATAAACTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGGACCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAATTGATGTCCAGCTATCCAAATTTAAA
AGTAAGTGTTCTCAAGGCAGGACATCACGGCTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGTTAGAACCATCAC
TTGCGCTTGTCTCAGCTGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAT
ATTAAGGTTTTACGCACAGACCAGGATGGTGCTATTCGGTTTAAGGGATGGTTCAAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.123	100	0.481
comEC/celB	Streptococcus mitis SK321	47.256	100	0.473
comEC/celB	Streptococcus pneumoniae TIGR4	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae D39	46.051	100	0.461
comEC/celB	Streptococcus pneumoniae Rx1	46.051	100	0.461
comEC/celB	Streptococcus pneumoniae R6	46.051	100	0.461
comEC	Lactococcus lactis subsp. cremoris KW2	44.475	97.051	0.432