Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL076_RS00380 Genome accession   NZ_LR134275
Coordinates   66288..67559 (+) Length   423 a.a.
NCBI ID   WP_003094929.1    Uniprot ID   -
Organism   Streptococcus vestibularis strain NCTC12167     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 61288..72559
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL076_RS00350 (NCTC12167_00070) - 61614..62051 (-) 438 WP_164555384.1 LytTR family DNA-binding domain-containing protein -
  EL076_RS00355 (NCTC12167_00071) - 62230..62535 (+) 306 WP_003094956.1 hypothetical protein -
  EL076_RS00360 (NCTC12167_00072) mutL 62585..64528 (+) 1944 WP_126428893.1 DNA mismatch repair endonuclease MutL -
  EL076_RS00365 (NCTC12167_00073) - 64659..64880 (+) 222 WP_002886321.1 hypothetical protein -
  EL076_RS00370 (NCTC12167_00074) ruvA 65038..65628 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA -
  EL076_RS00375 (NCTC12167_00075) - 65637..66191 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  EL076_RS00380 (NCTC12167_00076) cinA 66288..67559 (+) 1272 WP_003094929.1 competence/damage-inducible protein A Machinery gene
  EL076_RS00385 (NCTC12167_00077) recA 67595..68734 (+) 1140 WP_003094936.1 recombinase RecA Machinery gene
  EL076_RS00390 (NCTC12167_00078) spx 68911..69309 (+) 399 WP_003094927.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45966.16 Da        Isoelectric Point: 4.8459

>NTDB_id=1119859 EL076_RS00380 WP_003094929.1 66288..67559(+) (cinA) [Streptococcus vestibularis strain NCTC12167]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNENRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNDRQAQIVEGSVPLQNLTGLAVGGIITAQGVTYVVLPGPPSELKSM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTILKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFSGASQVFKGGFVTYSIEEKAKM
LDIPLSKLEENGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDTLEGHQAGTVFIGIADRNQVRSIKVVIGERSRSDV
RYISTLYAFNLVRQALLQEDNLI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1119859 EL076_RS00380 WP_003094929.1 66288..67559(+) (cinA) [Streptococcus vestibularis strain NCTC12167]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACTGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAACCGCCTACTTTCAGTTCTTG
ATCAGGCTAGTCAACGTAGCGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACTTAACCAAGCAAACA
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACACCTAATAATGATCGCCAAGCGCAAATTGTTGAGGGATCTGTACCCTTGCAAAATCTCACCGGTC
TAGCAGTTGGGGGGATTATTACTGCTCAAGGGGTGACCTATGTCGTCTTGCCTGGTCCACCAAGTGAACTCAAATCTATG
GTGAACCAAGAGCTTATTCCAGCTCTTACAGAGAATCATACTACTCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTCTTAAAGATCTCATTGTTAACCAAACGGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGACCTCATATATGGATATGGAGAATCAAACAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTTCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTTACCTATAGCATTGAAGAAAAAGCTAAAATG
TTAGATATTCCCTTATCTAAATTAGAAGAGAATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGCTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTGGCAGGACCAGATACATTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGGTCAATTAAGGTTGTTATAGGTGAAAGGAGTCGATCTGATGTC
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAAGACAACTTGATTTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.94

99.054

0.742
  cinA Streptococcus mitis NCTC 12261

73.747

99.054

0.73
  cinA Streptococcus pneumoniae TIGR4

72.315

99.054

0.716
  cinA Streptococcus pneumoniae Rx1

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

72.076

99.054

0.714
  cinA Streptococcus pneumoniae D39

71.838

99.054

0.712
  cinA Streptococcus mutans UA159

70.449

100

0.704
  cinA Streptococcus suis isolate S10

54.567

98.345

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

44.893

99.527

0.447

Multiple sequence alignment