Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ELZ47_RS00675 Genome accession   NZ_LR134002
Coordinates   122552..123808 (+) Length   418 a.a.
NCBI ID   WP_164549529.1    Uniprot ID   A0AAJ5NFU7
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 117552..128808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS00635 (NCTC10904_00124) - 118068..118577 (-) 510 WP_164549528.1 RDD family protein -
  ELZ47_RS00640 (NCTC10904_00125) - 118561..119064 (-) 504 WP_126434977.1 helix-turn-helix domain-containing protein -
  ELZ47_RS00645 (NCTC10904_00126) ruvA 119234..119824 (+) 591 WP_126434978.1 Holliday junction branch migration protein RuvA -
  ELZ47_RS00650 (NCTC10904_00127) - 119835..120407 (+) 573 WP_126434979.1 DNA-3-methyladenine glycosylase I -
  ELZ47_RS00655 (NCTC10904_00128) - 120417..121265 (-) 849 WP_002917851.1 helix-turn-helix domain-containing protein -
  ELZ47_RS00665 (NCTC10904_00130) - 121864..122142 (+) 279 WP_223310420.1 bacteriocin immunity protein -
  ELZ47_RS00675 (NCTC10904_00131) cinA 122552..123808 (+) 1257 WP_164549529.1 competence/damage-inducible protein A Machinery gene
  ELZ47_RS00680 (NCTC10904_00132) recA 123867..125015 (+) 1149 WP_002899282.1 recombinase RecA Machinery gene
  ELZ47_RS00685 (NCTC10904_00133) spx 125101..125499 (+) 399 WP_002894078.1 transcriptional regulator Spx -
  ELZ47_RS00690 (NCTC10904_00134) - 125635..126207 (+) 573 WP_125330729.1 SP0191 family lipoprotein -
  ELZ47_RS00695 (NCTC10904_00135) - 126313..126855 (+) 543 WP_125330730.1 hypothetical protein -
  ELZ47_RS00700 (NCTC10904_00136) - 127033..127299 (+) 267 WP_002894075.1 IreB family regulatory phosphoprotein -
  ELZ47_RS00705 (NCTC10904_00137) ruvX 127299..127718 (+) 420 WP_002911439.1 Holliday junction resolvase RuvX -
  ELZ47_RS00710 (NCTC10904_00138) - 127743..128054 (+) 312 WP_002894073.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44835.96 Da        Isoelectric Point: 4.6578

>NTDB_id=1117791 ELZ47_RS00675 WP_164549529.1 122552..123808(+) (cinA) [Streptococcus sanguinis strain NCTC 10904]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYFQTAVGDNENRLLSVLEIAQGRSNLIILTGGLGPTEDDLTKQT
LAKFLGRELNFDSQAVEKLDRFFASRPDYARTPNNERQAQLVEGSTPLLNATGLAVGGLLEVDGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILSEMIEQQSDPTIAPYAKTGEVTLRLSTKALSQAEADTKFEAVEKEI
LAHKTFEGQSLSEIFYGYGDDNSLAQVAFELLKGQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DIPLGDLEKHGVVSAFTAGKMAEQARKLTESDLAISLTGVAGPESLEDHPAGTVFIGLDSAAGTETIKVNIAGRSRRDVR
KIAVLHAFNLVRKTLLNS

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1117791 ELZ47_RS00675 WP_164549529.1 122552..123808(+) (cinA) [Streptococcus sanguinis strain NCTC 10904]
ATGAAAGCAGAAATTATTGCTGTGGGCACTGAGATTCTGACCGGTCAGATTGTCAATACCAATGCCCAATTTTTATCTGA
AAAACTGGCGAGTCTGGGGATTGATGTCTATTTTCAGACAGCAGTAGGGGACAATGAAAATCGTCTCCTCTCTGTTTTGG
AAATTGCTCAAGGACGCAGTAATCTAATTATCCTGACAGGAGGCTTGGGCCCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAGTTCTTAGGGCGTGAGCTTAATTTTGACTCACAGGCTGTGGAAAAGCTGGATCGCTTTTTTGCCAGCCGGCC
AGATTATGCTCGAACGCCCAACAATGAGCGTCAGGCCCAGCTAGTTGAAGGCTCGACTCCGTTACTAAATGCGACTGGTT
TAGCTGTTGGCGGTTTATTGGAAGTTGATGGAGTGACTTATGTAGTCCTGCCTGGTCCGCCTAGCGAGCTCAAGCCTATG
GTCAACAACGAGCTGGTTCCCCTCTTATCCACAGGTCAAAAGCTATATTCGAGGGTGCTACGCTTCTTTGGTATCGGCGA
GAGTCAGCTAGTGACTATTTTGTCAGAGATGATTGAGCAGCAGAGTGACCCCACCATTGCTCCTTATGCAAAGACGGGAG
AGGTTACCCTGCGACTGTCCACCAAGGCTCTGAGTCAGGCAGAAGCTGACACCAAGTTTGAGGCTGTGGAAAAGGAAATT
TTGGCACATAAGACTTTTGAAGGTCAGTCGCTGTCAGAGATTTTCTATGGTTATGGAGATGACAATTCCTTGGCTCAGGT
GGCTTTTGAGTTGCTGAAGGGTCAAGGGAAGACGATTTCAGCGGCAGAGAGTCTGACAGCTGGCCTCTTTCAAGCGACTT
TGGCAGATTTTGCTGGAGCCTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAGGAAAAGAGCCGGATGCTA
GATATACCGTTGGGAGACCTGGAGAAGCACGGTGTTGTTTCGGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACTGAAAGCGACTTAGCTATCAGTCTGACAGGTGTGGCAGGCCCAGAGTCGCTGGAAGACCATCCAGCAGGGACTG
TTTTTATCGGCTTAGATAGTGCTGCTGGAACAGAAACTATTAAGGTCAATATTGCTGGACGAAGTCGGCGTGATGTGCGG
AAAATTGCTGTTCTGCACGCCTTCAACCTAGTACGAAAAACTTTATTAAATAGCTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

78.177

99.761

0.78
  cinA Streptococcus mitis NCTC 12261

77.458

99.761

0.773
  cinA Streptococcus pneumoniae TIGR4

76.978

99.761

0.768
  cinA Streptococcus pneumoniae Rx1

76.978

99.761

0.768
  cinA Streptococcus pneumoniae R6

76.978

99.761

0.768
  cinA Streptococcus pneumoniae D39

76.739

99.761

0.766
  cinA Streptococcus mutans UA159

74.641

100

0.746
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

100

0.467

Multiple sequence alignment