Detailed information NTG1114370

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: AT689_RS03710
• Genome accession: NZ_LN831051
• Coordinates: 704097..704558 (+)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain NCTC7465
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 699097..709558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AT689_RS03675 (ERS445053_00719)	-	699589..700647 (+)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
AT689_RS03680 (ERS445053_00720)	-	700798..701163 (+)	366	WP_000286415.1	DUF1033 family protein	-
AT689_RS03685 (ERS445053_00721)	comGA/cglA/cilD	701239..702180 (+)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
AT689_RS03690 (ERS445053_00722)	comGB/cglB	702128..703144 (+)	1017	WP_001844679.1	competence type IV pilus assembly protein ComGB	Machinery gene
AT689_RS03695 (ERS445053_00723)	comGC/cglC	703146..703472 (+)	327	WP_000738633.1	comG operon protein ComGC	Machinery gene
AT689_RS03700 (ERS445053_00724)	comGD/cglD	703465..703869 (+)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
AT689_RS03705 (ERS445053_00725)	comGE/cglE	703832..704134 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AT689_RS03710 (ERS445053_00726)	comGF/cglF	704097..704558 (+)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
AT689_RS03715 (ERS445053_00727)	comGG/cglG	704536..704949 (+)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
AT689_RS12440	-	705086..705680 (+)	595	Protein_717	class I SAM-dependent methyltransferase	-
AT689_RS03730 (ERS445053_00729)	comYH	705741..706694 (+)	954	WP_000345130.1	class I SAM-dependent methyltransferase	Machinery gene
AT689_RS03735 (ERS445053_00730)	-	706745..707935 (+)	1191	WP_000167766.1	acetate kinase	-
AT689_RS13375	-	707936..708067 (+)	132	WP_000768904.1	hypothetical protein	-
AT689_RS03740 (ERS445053_00731)	rnpA	708084..708455 (+)	372	WP_000739246.1	ribonuclease P protein component	-
AT689_RS03745 (ERS445053_00732)	-	708430..709254 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=1114370 AT689_RS03710 WP_000250531.1 704097..704558(+) (comGF/cglF) [Streptococcus pneumoniae strain NCTC7465]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=1114370 AT689_RS03710 WP_000250531.1 704097..704558(+) (comGF/cglF) [Streptococcus pneumoniae strain NCTC7465]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915