Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LHA_RS07585 Genome accession   NZ_LN681225
Coordinates   1688865..1689968 (-) Length   367 a.a.
NCBI ID   WP_052673635.1    Uniprot ID   A0A0A8UPL4
Organism   Legionella hackeliae strain ATCC 35250     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1683865..1694968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LHA_RS07570 (LHA_1624) - 1684238..1685176 (-) 939 WP_231861994.1 hypothetical protein -
  LHA_RS17295 (LHA_1625) - 1685210..1685422 (-) 213 WP_231861995.1 hypothetical protein -
  LHA_RS07575 (LHA_1626) - 1685530..1687899 (-) 2370 WP_045106005.1 ankyrin repeat domain-containing protein -
  LHA_RS07580 (LHA_1627) - 1687998..1688858 (-) 861 WP_045106006.1 A24 family peptidase -
  LHA_RS07585 (LHA_1628) pilC 1688865..1689968 (-) 1104 WP_052673635.1 type II secretion system F family protein Machinery gene
  LHA_RS07590 (LHA_1629) pilB 1689961..1691619 (-) 1659 WP_045106007.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LHA_RS07595 (LHA_1630) - 1691724..1691951 (+) 228 WP_045106008.1 hypothetical protein -
  LHA_RS07600 (LHA_1631) - 1692042..1692782 (+) 741 WP_045106009.1 methyltransferase domain-containing protein -
  LHA_RS07605 (LHA_1632) - 1692873..1693199 (+) 327 WP_045107465.1 DUF1820 family protein -
  LHA_RS07610 (LHA_1633) - 1693224..1693784 (+) 561 WP_045106010.1 hypoxanthine-guanine phosphoribosyltransferase -
  LHA_RS07615 (LHA_1634) - 1693817..1694956 (-) 1140 WP_045106011.1 HlyD family type I secretion periplasmic adaptor subunit -

Sequence

Protein


Download         Length: 367 a.a.        Molecular weight: 40836.50 Da        Isoelectric Point: 9.5349

>NTDB_id=1113924 LHA_RS07585 WP_052673635.1 1688865..1689968(-) (pilC) [Legionella hackeliae strain ATCC 35250]
MINQSKFLAMLKKDQAWGLALTKKIHQTDITMFSRQMATMIGAGMPLVPAFDVIRRSTTNKHLKSLVLEIKDDIEASDSF
AEALHKHPTHFNSLFCSLIDAGEKSGTLAIMLDKIATYQERLDTVRRKVKKAMAYPLTVLLMAFFITSGLLMFVIPQFIV
LFQSFGAELPFLTRTIIHLSNIFQTYGYVLLGTFIGVIGGIIYRKKTSLDFSRRIDHILLKLPVFGLLLTKSIIARFSRT
LAITFSAGLPLMQALQAAGNVTGNRIYQLASCRIQDAIAYGQQLNLALENTGLFPALVIQIVAIGEESGTLEIMLNKIAD
YYEDEINHTIETLNILLEPFIMAILGIVIGTLLLAVYVPIFKLGSIM

Nucleotide


Download         Length: 1104 bp        

>NTDB_id=1113924 LHA_RS07585 WP_052673635.1 1688865..1689968(-) (pilC) [Legionella hackeliae strain ATCC 35250]
ATGATTAATCAATCTAAATTTTTAGCTATGTTAAAAAAAGACCAAGCATGGGGACTTGCTCTTACAAAGAAAATCCATCA
AACAGACATTACAATGTTTAGTCGACAAATGGCAACGATGATTGGTGCTGGCATGCCGTTAGTACCCGCATTTGATGTGA
TAAGAAGAAGCACCACTAATAAGCATTTGAAGTCATTGGTATTAGAAATAAAAGACGATATTGAAGCAAGCGATTCATTT
GCTGAGGCACTACATAAACATCCGACACATTTTAATTCACTATTCTGTAGTCTTATTGACGCAGGAGAAAAGTCAGGCAC
GCTGGCAATTATGCTTGATAAGATCGCAACCTATCAAGAAAGACTTGATACGGTGCGAAGAAAAGTTAAAAAGGCAATGG
CTTATCCCCTGACAGTTTTACTAATGGCCTTTTTCATTACCAGTGGATTATTAATGTTCGTTATTCCTCAATTCATTGTC
TTATTTCAATCATTTGGTGCTGAACTTCCTTTTCTTACAAGAACCATTATTCATCTATCAAATATATTTCAAACGTATGG
ATATGTCCTCTTAGGAACTTTTATCGGAGTTATTGGCGGTATAATTTATCGCAAAAAGACATCATTAGATTTTTCTCGCC
GAATCGATCACATCTTGCTAAAACTACCAGTATTTGGACTGCTGTTAACCAAATCTATCATCGCGAGATTCTCGCGGACA
TTAGCAATTACTTTTTCAGCAGGTTTACCACTCATGCAAGCATTACAAGCGGCAGGAAATGTAACAGGTAATCGCATCTA
TCAATTAGCAAGTTGCCGTATTCAAGATGCAATTGCTTATGGCCAACAACTGAATCTGGCCTTAGAAAATACAGGTCTAT
TTCCTGCTCTAGTTATTCAAATAGTTGCTATTGGTGAAGAGTCAGGAACCCTTGAGATAATGTTAAATAAAATTGCAGAT
TACTATGAAGACGAAATAAATCATACTATTGAAACGCTTAATATTTTATTAGAACCATTTATCATGGCAATATTAGGTAT
TGTGATAGGAACTCTATTGCTAGCTGTCTACGTTCCTATTTTTAAACTTGGCTCTATAATGTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-156)

Type II secretion system (T2SS), protein F (T2SSF)

(237-359)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A8UPL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

54.651

93.733

0.512
  pilC Acinetobacter baylyi ADP1

45.533

94.55

0.431
  pilC Acinetobacter baumannii D1279779

45.507

94.005

0.428
  pilC Pseudomonas stutzeri DSM 10701

44.348

94.005

0.417
  pilG Neisseria meningitidis 44/76-A

40.688

95.095

0.387
  pilG Neisseria gonorrhoeae MS11

40.58

94.005

0.381
  pilC Vibrio campbellii strain DS40M4

38.218

94.823

0.362

Multiple sequence alignment