Detailed information NTG1113406

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: A3I7_RS0103680
• Genome accession: NZ_KB904458
• Coordinates: 13078..13989 (-)
• Length: 303 a.a.
• NCBI ID: WP_018375433.1
• Uniprot ID: -
• Organism: Streptococcus orisratti DSM 15617
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 8078..18989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A3I7_RS0103650	-	9310..9690 (-)	381	WP_018375427.1	membrane protein	-
A3I7_RS0103655	-	9708..10136 (-)	429	WP_018375428.1	low molecular weight protein-tyrosine-phosphatase	-
A3I7_RS0103660	ruvB	10427..11428 (-)	1002	WP_026217115.1	Holliday junction branch migration DNA helicase RuvB	-
-	comS	11715..11813 (-)	99	-	-	Regulator
A3I7_RS0103670	comR	11893..12798 (-)	906	WP_018375431.1	helix-turn-helix domain-containing protein	Regulator
A3I7_RS14000	-	12875..13042 (-)	168	Protein_11	XRE family transcriptional regulator	-
A3I7_RS0103680	comR	13078..13989 (-)	912	WP_018375433.1	helix-turn-helix domain-containing protein	Regulator
A3I7_RS0103685	purB	14206..15504 (-)	1299	WP_018375434.1	adenylosuccinate lyase	-
A3I7_RS0103690	-	15515..17266 (-)	1752	WP_018375435.1	RNA-directed DNA polymerase	-
A3I7_RS0103695	purK	17293..18366 (-)	1074	WP_018375436.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
A3I7_RS0103700	purE	18353..18841 (-)	489	WP_026217116.1	5-(carboxyamino)imidazole ribonucleotide mutase	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35800.35 Da
• Isoelectric Point: 4.6971

>NTDB_id=1113406 A3I7_RS0103680 WP_018375433.1 13078..13989(-) (comR) [Streptococcus orisratti DSM 15617]
MLGDFGVKVRQLRESKGIAREEFCGDETELSVRQLARIETGSLPTLSKAQFIAKRLGVSLGELTDGESLELPDRYKELKY
LILRTPTYMDSEKLKVREEQFDEIYEDYYDKLPEEEKLMVTFIQSKFEVYQTGNVDFGTEVIKDYFNQLKKRKLYKLNDL
VLIELFLLCSVVSNFDKTIFDEIFYEKIKTNLINQSQTLPIEDLYLLNSILLVCADVSVRLQRYDDLDRILLISHQIMTK
IQDFQKMPIYYMLKWEYCWFGLNDFKQAEECYKQAILFAGVINGDYLVNKLEEEWRKLVSKIN

Nucleotide

• Length: 912 bp

>NTDB_id=1113406 A3I7_RS0103680 WP_018375433.1 13078..13989(-) (comR) [Streptococcus orisratti DSM 15617]
ATGCTTGGTGATTTTGGAGTTAAGGTCCGACAGTTAAGAGAATCAAAAGGAATTGCGAGAGAGGAGTTTTGCGGAGATGA
AACTGAACTTTCAGTTAGGCAATTAGCAAGAATAGAAACTGGATCGCTACCGACCTTGTCGAAAGCTCAGTTTATAGCGA
AGCGACTGGGTGTTAGTCTTGGAGAATTGACAGATGGGGAGAGCTTAGAACTTCCAGATCGTTATAAAGAATTGAAATAC
TTGATTTTACGAACACCAACATATATGGATTCAGAGAAACTCAAAGTTCGTGAAGAACAGTTTGATGAAATTTATGAGGA
TTATTATGATAAACTACCAGAGGAAGAAAAACTGATGGTTACTTTTATTCAATCCAAATTTGAAGTATATCAAACTGGTA
ATGTTGATTTTGGAACAGAAGTAATCAAAGATTATTTTAATCAGTTAAAAAAGAGAAAGTTATATAAATTAAATGACCTA
GTTTTGATAGAACTTTTTCTCCTTTGTTCGGTTGTTTCCAATTTTGATAAGACAATTTTTGATGAGATATTTTATGAAAA
AATAAAAACTAATCTTATCAATCAATCACAAACTTTACCTATAGAGGATTTATATTTGTTGAATAGCATCTTGCTTGTTT
GTGCAGATGTATCAGTTCGATTACAGCGATATGATGATCTGGATAGGATATTACTGATAAGCCATCAGATAATGACAAAA
ATTCAGGATTTTCAAAAAATGCCCATCTATTATATGCTAAAATGGGAATATTGTTGGTTTGGCTTGAATGATTTTAAACA
AGCTGAAGAATGTTATAAACAGGCTATTTTATTCGCTGGAGTAATAAACGGTGACTATCTTGTAAATAAGTTAGAAGAAG
AATGGAGAAAATTAGTATCCAAAATAAATTAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (72-295)

• Helix-turn-helix (HTH_3) (9-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	57.756	100	0.578
comR	Streptococcus pyogenes MGAS8232	49.333	99.01	0.488
comR	Streptococcus mutans UA159	46.98	98.35	0.462
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	48.951	94.389	0.462
comR	Streptococcus suis P1/7	43.537	97.03	0.422
comR	Streptococcus suis 05ZYH33	43.537	97.03	0.422
comR	Streptococcus suis D9	38.305	97.36	0.373