Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   H702_RS02320 Genome accession   NZ_AUZH01000012
Coordinates   1410..3557 (-) Length   715 a.a.
NCBI ID   WP_039696223.1    Uniprot ID   -
Organism   Streptococcus equinus JB1     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..8557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H702_RS02315 (H702_02395) - 18..1400 (-) 1383 WP_039696222.1 bacteriocin secretion accessory protein -
  H702_RS02320 (H702_02400) comA/nlmT 1410..3557 (-) 2148 WP_039696223.1 peptide cleavage/export ABC transporter Regulator
  H702_RS09975 (H702_02405) - 3797..3961 (+) 165 WP_074799080.1 Blp family class II bacteriocin -
  H702_RS02325 (H702_02410) - 4003..4212 (+) 210 WP_039696224.1 hypothetical protein -
  H702_RS02335 (H702_02420) - 4472..5086 (+) 615 WP_052071090.1 thioredoxin fold domain-containing protein -
  H702_RS02345 (H702_02430) comE/comE1 5873..6604 (+) 732 WP_039696227.1 response regulator transcription factor Regulator
  H702_RS10470 comD/comD1 7219..7941 (+) 723 WP_236726575.1 sensor histidine kinase Regulator
  H702_RS10235 (H702_02440) comC/comC1 7951..8094 (-) 144 WP_160172983.1 hypothetical protein Regulator
  H702_RS02355 (H702_02445) - 8358..8507 (+) 150 WP_039696228.1 hypothetical protein -

Sequence

Protein


Download         Length: 715 a.a.        Molecular weight: 80005.20 Da        Isoelectric Point: 8.9548

>NTDB_id=111302 H702_RS02320 WP_039696223.1 1410..3557(-) (comA/nlmT) [Streptococcus equinus JB1]
MRRYKYVSQIDMRDCGVAALASVAKHYGSRFSLAHLRELAKTNKEGTTALGIVEAAKKIGFETRAVKADMALFEMDDIPY
PCIVHVNKQGKLQHYSVIYKAKKDYLIIGDPDPSVGVTKIAKADFAKEWTGVTIFLAPAASYKPHKDKKNGLMSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNQLQSTLGIVSIGLVVTYIMQQIMSFSQQYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNAKLFLITLIALPVYAVII
FAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEETRYRNIDSEFVEYLDKSFTLNKYEAMQASLKQGAQLIL
NVAILWYGSRLVMTGKISVGQLITYNTLLSYFTKPMENIINLQTKLQSAKVANKRLNEVYLVSSEFDNKQVIDNQEFLKG
DLVFDDVSYKYGFGRDTLSHIKLRIKEGEKVSLVGVSGSGKTTLAKMMVNFYSPNQGQITLGGYDYKTIDKKVLRQHINY
LPQQSYVFSGSILDNLTLGASDAITQEDIIKACEIAEIRADIEAMPMAYHTELSDGAGLSGGQKQRLAIARALLTKSPVL
ILDEATSGLDVLTEKRVIHNLLALKDKTIIFVAHRLSIAKQTDRVIVLDKGQIIEQGHHEQLMQNPGFYAQLFQE

Nucleotide


Download         Length: 2148 bp        

>NTDB_id=111302 H702_RS02320 WP_039696223.1 1410..3557(-) (comA/nlmT) [Streptococcus equinus JB1]
ATGAGGAGATACAAATACGTTAGTCAGATTGATATGCGAGATTGTGGGGTAGCTGCTTTGGCATCAGTTGCTAAACACTA
CGGCTCACGCTTTTCGCTTGCTCACTTAAGGGAACTGGCTAAGACTAATAAAGAAGGAACAACTGCTCTTGGAATCGTCG
AGGCAGCCAAAAAGATTGGCTTTGAGACACGCGCTGTAAAAGCTGATATGGCACTTTTTGAGATGGATGATATCCCGTAT
CCTTGTATTGTCCATGTGAATAAGCAAGGAAAACTGCAACACTATTCTGTCATCTATAAGGCTAAAAAAGATTATCTAAT
CATCGGTGATCCTGACCCAAGTGTGGGAGTCACAAAAATAGCTAAAGCTGATTTTGCCAAAGAATGGACAGGGGTTACGA
TCTTTCTAGCTCCTGCAGCTAGCTATAAACCACATAAGGATAAGAAAAATGGCTTGATGAGTTTCTTACCGATTATTTTT
AAGCAAAAAGCACTACTAACATATATAATCCTTGCTAGCTTACTTGTAACTTTGATTAATATTGTCGGCTCTTATTATCT
TCAAGGAATCTTAGATGATTATATTCCTAACCAACTGCAATCGACCCTTGGAATTGTCTCAATCGGCTTGGTCGTGACTT
ACATCATGCAACAGATTATGAGCTTCTCACAACAGTATTTGTTAGTTGTGCTCAGTCAACGTTTGACGATTGATGTCATT
TTATCTTATATTCGTCATATTTTCGAATTGCCCATGTCCTTTTTTGCGACAAGACGAACTGGGGAAGTAATTTCACGCTT
TACCGACGCCAACTCTATCATCGATGCCCTTGCTTCAACAATCTTATCGCTTTTTCTCGATGTGAGTATCCTTTTCATCG
TTGGCAGTGTCTTGATTTTGCAAAATGCGAAACTCTTCTTGATAACCTTAATTGCTTTGCCTGTTTATGCCGTCATTATC
TTTGCTTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAAGCCAATTCTATGGTCAGCTCTGCCATTATTGA
AGATATCAACGGGATTGAAACCATTAAATCACTAACTAGCGAGGAGACACGTTATCGCAATATCGATAGCGAATTCGTGG
AATACTTGGATAAAAGTTTCACGCTTAATAAATACGAAGCAATGCAAGCCTCACTTAAGCAAGGAGCACAGCTGATTTTA
AATGTGGCTATTCTCTGGTACGGCTCACGTCTCGTTATGACAGGGAAGATTTCTGTAGGGCAGTTGATTACCTACAACAC
CCTTTTATCTTACTTCACAAAACCAATGGAAAACATTATTAACTTGCAAACTAAGTTACAGTCAGCGAAAGTTGCTAACA
AGCGTCTTAACGAAGTTTATCTGGTATCTTCTGAATTTGATAACAAACAAGTGATTGATAATCAAGAGTTTCTCAAAGGT
GATCTTGTCTTTGATGATGTTTCCTATAAATACGGCTTTGGACGCGATACTCTTAGTCACATTAAACTTCGTATCAAGGA
AGGTGAAAAGGTTAGCCTCGTCGGCGTTAGTGGCTCTGGAAAAACGACTTTGGCTAAGATGATGGTAAACTTTTATAGTC
CAAATCAAGGTCAAATCACCTTGGGAGGCTACGACTATAAAACTATTGATAAAAAAGTTCTTCGTCAACACATCAACTAC
CTTCCACAACAATCTTACGTCTTTTCTGGAAGTATCCTTGATAATCTCACTTTAGGTGCTTCTGATGCGATTACTCAAGA
AGACATTATCAAGGCCTGTGAAATCGCTGAAATTCGTGCTGACATTGAAGCTATGCCAATGGCTTACCACACTGAGTTAT
CAGATGGGGCTGGTTTATCTGGCGGTCAAAAACAGCGATTAGCTATTGCCAGAGCACTTCTGACTAAGTCACCCGTCTTA
ATCCTAGATGAAGCGACAAGTGGTCTTGATGTGCTGACCGAAAAACGTGTTATCCACAATTTGTTAGCTCTAAAAGACAA
AACCATTATCTTTGTTGCTCACCGCTTAAGCATTGCCAAACAAACTGACCGTGTCATCGTCCTAGATAAAGGACAAATTA
TCGAACAAGGTCATCACGAGCAACTCATGCAAAATCCTGGCTTTTACGCTCAGCTATTTCAAGAATAA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(3-140)

ABC transporter (ABC_tran)

(498-647)

ABC transporter transmembrane region (ABC_membrane)

(166-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

69.285

99.72

0.691
  comA Streptococcus mitis NCTC 12261

66.384

99.021

0.657
  comA Streptococcus pneumoniae Rx1

65.395

99.021

0.648
  comA Streptococcus pneumoniae D39

65.395

99.021

0.648
  comA Streptococcus pneumoniae R6

65.395

99.021

0.648
  comA Streptococcus mitis SK321

65.395

99.021

0.648
  comA Streptococcus pneumoniae TIGR4

65.113

99.021

0.645
  comA Streptococcus gordonii str. Challis substr. CH1

64.045

99.58

0.638

Multiple sequence alignment