Detailed information NTG1112408

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: KJB05_RS18060
• Genome accession: NZ_HG992742
• Coordinates: 3983489..3984598 (-)
• Length: 369 a.a.
• NCBI ID: WP_208445678.1
• Uniprot ID: A0A812GYX1
• Organism: Vibrio sp. B1ASS3
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	3982093..3983301	3983489..3984598	flank	188

Gene organization within MGE regions

Location: 3982093..3984598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KJB05_RS18050 (ACOMICROBIO_LOCUS2465)	-	3982093..3983301 (+)	1209	WP_001352368.1	IS4-like element ISVsa5 family transposase	-
KJB05_RS18055 (ACOMICROBIO_NCLOACGD_03661)	-	3983316..3983486 (-)	171	Protein_3431	DUF494 family protein	-
KJB05_RS18060 (ACOMICROBIO_LOCUS2466)	dprA	3983489..3984598 (-)	1110	WP_208445678.1	DNA-processing protein DprA	Machinery gene

Sequence

Protein

• Length: 369 a.a.
• Molecular weight: 39403.11 Da
• Isoelectric Point: 6.3382

>NTDB_id=1112408 KJB05_RS18060 WP_208445678.1 3983489..3984598(-) (dprA) [Vibrio sp. B1ASS3]
MKPHNDTDLAAWLKLSCLPGIGGVKLSKLLSKDTPSNIVQYSTEQLQLLGLTAKQLQAWSKVDKEVDACLTWAAASSHHH
ILTLADALYPPLLKQTVAPPPLLFVKGDASCLSQPQIAMVGSRNASVDGLQHARSFASDLVQHDLIVTSGLALGIDGHAH
DGALLAGGKTIAVLGSGLEQVYPARHRGLAQRVMENGALVSEFRPDAKPRAENFPRRNRIISGLSLGVLVVEAAEKSGSL
ITARYALEQGREVFALPASINAPNASGGNQLIRNGACLVQNTQEVLNEIQSLLDWSINQSLDLFSAPIDEEELPFPQLLA
NVGNEATPVDILASRTNIPVQEVMMQLLELELSGHVVAVSGGYIRKGRG

Nucleotide

• Length: 1110 bp

>NTDB_id=1112408 KJB05_RS18060 WP_208445678.1 3983489..3984598(-) (dprA) [Vibrio sp. B1ASS3]
ATGAAACCACACAATGATACGGATCTCGCCGCCTGGTTAAAGCTGAGTTGCTTGCCAGGTATTGGCGGGGTCAAGCTGAG
TAAGCTACTGAGCAAAGACACGCCGAGTAATATTGTCCAATATTCCACGGAGCAGCTTCAGCTTTTAGGTTTAACGGCGA
AACAACTGCAAGCGTGGTCGAAGGTCGATAAAGAAGTCGATGCTTGTCTGACTTGGGCTGCTGCATCTTCTCATCATCAT
ATTCTTACTTTGGCGGATGCTTTGTATCCGCCACTTCTCAAACAAACCGTCGCACCGCCTCCTTTATTATTCGTAAAGGG
AGACGCGAGCTGCTTGTCTCAGCCACAAATAGCCATGGTTGGCAGTCGTAATGCCAGCGTGGATGGACTACAACATGCAA
GAAGCTTTGCATCAGACTTGGTACAACACGATCTGATCGTCACCAGTGGTTTAGCATTAGGTATTGATGGTCATGCTCAT
GATGGCGCGCTTTTAGCTGGCGGTAAAACCATCGCAGTGCTTGGTTCTGGGTTGGAACAAGTGTACCCAGCAAGACACCG
AGGTTTGGCGCAGCGAGTGATGGAAAATGGTGCGCTTGTCTCTGAGTTTCGTCCTGATGCTAAACCTCGCGCAGAAAACT
TCCCACGTCGTAATCGAATTATCAGTGGTTTGTCGCTGGGTGTTTTGGTGGTGGAAGCGGCTGAAAAAAGTGGTTCCTTA
ATCACTGCTCGCTATGCCCTTGAGCAAGGTCGAGAAGTTTTCGCTCTGCCAGCTTCGATTAATGCTCCTAACGCCAGTGG
TGGTAATCAATTGATTCGTAACGGGGCTTGCCTCGTACAAAATACTCAAGAGGTGCTGAATGAAATACAGTCTTTACTCG
ACTGGTCTATTAATCAGAGCTTAGATTTATTTTCTGCGCCAATTGATGAAGAAGAATTGCCATTTCCTCAGCTGTTAGCT
AACGTAGGAAATGAGGCTACACCAGTTGATATTCTTGCAAGCAGGACCAATATACCTGTCCAAGAAGTCATGATGCAGCT
CTTAGAGCTTGAGCTTTCAGGGCATGTTGTTGCAGTATCCGGTGGCTATATTCGAAAGGGGAGGGGCTAG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (307-362)

• DNA recombination-mediator protein A (DNA_processg_A) (77-280)

3D structure

• AlphaFold DB: A0A812GYX1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Vibrio campbellii strain DS40M4	96.477	100	0.965
dprA	Vibrio cholerae strain A1552	58.649	100	0.588
dprA	Glaesserella parasuis strain SC1401	47.733	100	0.485
dprA	Legionella pneumophila strain ERS1305867	44.444	97.561	0.434
dprA	Haemophilus influenzae Rd KW20	45	92.141	0.415
dprA	Neisseria meningitidis strain C311	36.504	100	0.385
dprA	Neisseria meningitidis MC58	36.504	100	0.385
dprA	Neisseria gonorrhoeae MS11	36.176	100	0.379
dprA	Neisseria gonorrhoeae strain FA1090	35.917	100	0.377