Detailed information NTG1111744

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: HMPREF9425_RS04210
• Genome accession: NZ_GL831112
• Coordinates: 850735..851442 (+)
• Length: 235 a.a.
• NCBI ID: WP_003093060.1
• Uniprot ID: -
• Organism: Streptococcus vestibularis ATCC 49124
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 845735..856442

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS04185 (HMPREF9425_0872)	-	846871..847059 (+)	189	WP_003097027.1	DNA-directed RNA polymerase subunit beta	-
HMPREF9425_RS04190 (HMPREF9425_0873)	endA	847121..848002 (+)	882	WP_003097029.1	DNA/RNA non-specific endonuclease	Machinery gene
HMPREF9425_RS04195	-	848080..848196 (-)	117	Protein_848	amino acid ABC transporter permease	-
HMPREF9425_RS04200 (HMPREF9425_0876)	-	849106..849778 (-)	673	WP_003097031.1	transporter substrate-binding domain-containing protein	-
HMPREF9425_RS04205 (HMPREF9425_0877)	-	849788..850412 (-)	625	WP_003097033.1	amino acid ABC transporter ATP-binding protein	-
HMPREF9425_RS04210 (HMPREF9425_0878)	vicR	850735..851442 (+)	708	WP_003093060.1	response regulator YycF	Regulator
HMPREF9425_RS04215 (HMPREF9425_0879)	vicK	851435..852775 (+)	1341	WP_003097035.1	cell wall metabolism sensor histidine kinase VicK	Regulator
HMPREF9425_RS04220 (HMPREF9425_0880)	vicX	852781..853593 (+)	813	WP_037621682.1	MBL fold metallo-hydrolase	Regulator
HMPREF9425_RS04225 (HMPREF9425_0881)	-	853654..854013 (+)	360	WP_003097039.1	YbaN family protein	-
HMPREF9425_RS04230 (HMPREF9425_0882)	-	854068..855282 (-)	1215	WP_003097042.1	aminoacyltransferase	-
HMPREF9425_RS04235 (HMPREF9425_0883)	yidA	855284..856093 (-)	810	WP_003097045.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27073.95 Da
• Isoelectric Point: 4.8387

>NTDB_id=1111744 HMPREF9425_RS04210 WP_003093060.1 850735..851442(+) (vicR) [Streptococcus vestibularis ATCC 49124]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1111744 HMPREF9425_RS04210 WP_003093060.1 850735..851442(+) (vicR) [Streptococcus vestibularis ATCC 49124]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATATCGGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGTCGAGAAGCTTTAGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATCCTGGACTTGA
TGTTGCCTGAACTGGATGGCTTGGAAGTAGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATTATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACTATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AGCAGGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTCGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTGCTCTTCCATTTGGCAACACATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGTTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACTATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.957	100	0.86
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.455	98.298	0.447
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
scnR	Streptococcus mutans UA159	38.559	100	0.387